ETV6 Monoclonal antibody 67579-1-Ig proteintech
$149.00
In stock
SKU
67579-1-Ig
| Catalog Number | 67579-1-Ig |
| Synonyms | ETS related protein Tel1, ETS translocation variant 6, ets variant 6, ETV6, TEL, TEL/ABL, TEL1, Transcription factor ETV6 |
| Host | Mouse |
| Reactivity | Human |
| Reactivity | human |
| Form | Liquid |
| Formulation | PBS, Azide, Glycerol |
| Applications | WB, IHC, ELISA |
| Host / Isotype | Mouse / IgG1 |
| Tested Applications — Positive WB detected in | Jurkat cells, U2OS cells, A431 cells, K-562 cells, THP-1 cells |
| Tested Applications — Positive IHC detected in | human breast cancer tissue, human lung cancer tissue Note: suggested antigen retrieval with TE buffer pH 9.0; (*) Alternatively, antigen retrieval may be performed with citrate buffer pH 6.0 |
| Recommended Dilutions — Western Blot (WB) | WB : 1:1000-1:6000 |
| Recommended Dilutions — Immunohistochemistry (IHC) | IHC : 1:50-1:500 |
| Positive WB detected in | Jurkat cells, U2OS cells, A431 cells, K-562 cells, THP-1 cells |
| Positive IHC detected in | human breast cancer tissue, human lung cancer tissue Note: suggested antigen retrieval with TE buffer pH 9.0; (*) Alternatively, antigen retrieval may be performed with citrate buffer pH 6.0 |
| Western Blot (WB) | WB : 1:1000-1:6000 |
| Immunohistochemistry (IHC) | IHC : 1:50-1:500 |
| Tested Reactivity | Human |
| Class | Monoclonal |
| Type | Antibody |
| Immunogen | CatNo: Ag30054 Product name: Recombinant human ETV6 protein Source: e coli. -derived, PET28a Tag: 6*His Domain: 150-312 aa of BC043399 Sequence: QNHEEDNCVQRTPRPSVDNVHHNPPTIELLHRSRSPITTNHRPSPDPEQRPLRSPLDNMIRRLSPAERAQGPRPHQENNHQESYPLSVSPMENNHCPASSESHPKPSSPRQESTRVIQLMPSPIMHPLILNPRHSVDFKQSRLSEDGLHREGKPINLSHREDL Predict reactive species |
| Full Name | ets variant 6 |
| Calculated Molecular Weight | 452 aa, 53 kDa |
| Observed Molecular Weight | 60 kDa |
| GenBank Accession Number | BC043399 |
| Gene Symbol | ETV6 |
| Gene ID (NCBI) | 2120 |
| RRID | AB_2918493 |
| Conjugate | Unconjugated |
| Purification Method | Protein G purification |
| UNIPROT ID | P41212 |
| Storage Buffer | PBS with 0.02% sodium azide and 50% glycerol, pH 7.3. |
| Storage Conditions | Store at -20°C. Aliquoting is unnecessary for -20 o C storage. 20ul sizes contain 0.1% BSA. |
| IHC protocol for ETV6 antibody 67579-1-Ig | Download protocol |
| WB protocol for ETV6 antibody 67579-1-Ig | Download protocol |
| Citations | - |
| Dilutions | WB : 1:1000-1:6000 IHC : 1:50-1:500 |
| Isotype | IgG1 |
| Clonality | Monoclonal |
| Clone Number | 2A5A2 |
| Conjugation | Unconjugated |
ETV6(ETS Variant Transcription Factor 6), also known as TEL, is a Protein Coding gene. ETV6 is a member of the ETS family of transcription factors encoded by the ETS variant 6 gene (ETV6), located on chromosome 12p13.2. ETV6 protein contains 3 domains: a) the pointed N-terminal (i.e. PNT) domain which forms oligomer partners with itself as well as other transcription factors (e.g. FLI1) and is required for ETV6's transcriptional repressing activity; b) the central regulatory domain; and c) the C-terminal DNA-binding domain(PMID: 22578774). ETV6 is highly expressed in early hematopoietic progenitor cells(HPCs) and is essential for hematopoiesis in the bone marrow(PMID: 31248877). Protocols Product Specific Protocols IHC protocol for ETV6 antibody 67579-1-Ig Download protocol WB protocol for ETV6 antibody 67579-1-Ig Download protocol Standard Protocols Click here to view our Standard Protocols
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