| Catalog Number | 68456-1-Ig |
| Synonyms | 2A4C6, EAP1, Exosome complex component RRP42, Exosome component 7, hRrp42p |
| Host | Mouse |
| Reactivity | human, mouse, rat, pig, rabbit |
| Form | Liquid |
| Formulation | PBS, Azide, Glycerol |
| Applications | WB, ELISA |
| Host / Isotype | Mouse / IgG1 |
| Tested Applications — Positive WB detected in | Saos-2 cells, HSC-T6 cells, PANC-1 cells, NIH/3T3 cells, 4TA cells, HT-29 cells, LNCaP cells, MDA-MB-231 cells, IMR-32 cells, rat brain tissue, mouse brain tissue, rabbit brain tissue, pig brain tissue, Caco-2 cells, HeLa cells, HEK-293 cells |
| Recommended Dilutions — Western Blot (WB) | WB : 1:5000-1:50000 |
| Positive WB detected in | Saos-2 cells, HSC-T6 cells, PANC-1 cells, NIH/3T3 cells, 4TA cells, HT-29 cells, LNCaP cells, MDA-MB-231 cells, IMR-32 cells, rat brain tissue, mouse brain tissue, rabbit brain tissue, pig brain tissue, Caco-2 cells, HeLa cells, HEK-293 cells |
| Western Blot (WB) | WB : 1:5000-1:50000 |
| Tested Reactivity | human, mouse, rat, pig, rabbit |
| Class | Monoclonal |
| Type | Antibody |
| Immunogen | CatNo: Ag18322 Product name: Recombinant human EXOSC7 protein Source: e coli. -derived, PET28a Tag: 6*His Domain: 1-291 aa of BC012831 Sequence: MASVTLSEAEKVYIVHGVQEDLRVDGRGCEDYRCVEVETDVVSNTSGSARVKLGHTDILVGVKAEMGTPKLEKPNEGYLEFFVDCSASATPEFEGRGGDDLGTEIANTLYRIFNNKSSVDLKTLCISPREHCWVLYVDVLLLECGGNLFDAISIAVKAALFNTRIPRVRVLEDEEGSKDIELSDDPYDCIRLSVENVPCIVTLCKIGYRHVVDATLQEEACSLASLLVSVTSKGVVTCMRKVGKGSLDPESIFEMMETGKRVGKVLHASLQSVLHKEESLGPKRQKVGFLG Predict reactive species |
| Full Name | exosome component 7 |
| Calculated Molecular Weight | 291 aa, 32 kDa |
| Observed Molecular Weight | 35 kDa |
| GenBank Accession Number | BC012831 |
| Gene Symbol | EXOSC7 |
| Gene ID (NCBI) | 23016 |
| RRID | AB_3085168 |
| Conjugate | Unconjugated |
| Purification Method | Protein G purification |
| UNIPROT ID | Q15024 |
| Storage Buffer | PBS with 0.02% sodium azide and 50% glycerol, pH 7.3. |
| Storage Conditions | Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20 o C storage. 20ul sizes contain 0.1% BSA. |
| WB protocol for EXOSC7 antibody 68456-1-Ig | Download protocol |
| Citations | - |
| Dilutions | WB : 1:5000-1:50000 |
| Isotype | IgG1 |
| Clonality | Monoclonal |
| Clone Number | 2A4C6 |
| Conjugation | Unconjugated |
In the nucleus, the RNA exosome complex is involved in proper maturation of stable RNA species such as rRNA, snRNA and snoRNA, in the elimination of RNA processing by-products and non-coding 'pervasive' transcripts, such as antisense RNA species and promoter-upstream transcripts and of mRNAs with processing defects, thereby limiting or excluding their export to the cytoplasm. EXOSC7 also named as RRP42 or EAP1 is a 291 amino acid protein, which belongs to the RNase PH family. EXOSC7 is one of the six RNase-PH domain subunits of the exosome and required for the processing of the 7S pre-RNA. Protocols Product Specific Protocols WB protocol for EXOSC7 antibody 68456-1-Ig Download protocol Standard Protocols Click here to view our Standard Protocols
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