FAM86A Polyclonal antibody 32472-1-AP proteintech
$149.00
In stock
SKU
32472-1-AP
| Catalog Number | 32472-1-AP |
| Synonyms | EC:2.1.1.-, EEF2KMT, eEF2-KMT, eEF2-lysine methyltransferase, Eukaryotic Elongation Factor 2 Lysine Methyltransferase |
| Host | Rabbit |
| Reactivity | human |
| Form | Liquid |
| Formulation | PBS, Azide, Glycerol |
| Applications | WB, ELISA |
| Host / Isotype | Rabbit / IgG |
| Tested Applications — Positive WB detected in | MCF-7 cells |
| Recommended Dilutions — Western Blot (WB) | WB : 1:1000-1:4000 |
| Positive WB detected in | MCF-7 cells |
| Western Blot (WB) | WB : 1:1000-1:4000 |
| Tested Reactivity | human |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | CatNo: Ag38481 Product name: Recombinant human FAM86A protein Source: e coli. -derived, PGEX-4T Tag: GST Domain: 1-330 aa of BC010084 Sequence: MAPEENAGTELLLQSFERRFLAARTLRSFPWQSLEAKLRDSSDSELLRDILHKTVKHPVCVKHPPSVKYARCFLSELIKKHEAVHTEPLDELYEALAETLMAKESTQGHRSYLLPSGGSVTLSESTAIISYGTTGLVTWDAALYLAEWAIENPAVFTNRTVLELGSGAGLTGLAICKMCRPRAYIFSDCHSRVLEQLRGNVLLNGLSLEADITAKLDSPRVTVAQLDWDVATVHQLSAFQPDVVIAADVLYCPEAIMSLVGVLRRLAACREDQRAPEVYVAFTVRNPETCQLFTTELGRAGIRWEVEPRHEQKLFPYEEHLEMAMLNLTL Predict reactive species |
| Full Name | family with sequence similarity 86, member A |
| Observed Molecular Weight | 38 kDa |
| GenBank Accession Number | BC010084 |
| Gene Symbol | FAM86A |
| Gene ID (NCBI) | 196483 |
| RRID | AB_3742623 |
| Conjugate | Unconjugated |
| Purification Method | Antigen affinity Purification |
| UNIPROT ID | Q96G04 |
| Storage Buffer | PBS with 0.02% sodium azide and 50% glycerol, pH 7.3. |
| Storage Conditions | Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20 o C storage. 20ul sizes contain 0.1% BSA. |
| WB protocol for FAM86A antibody 32472-1-AP | Download protocol |
| Citations | - |
| Dilutions | WB : 1:1000-1:4000 |
| Isotype | IgG |
| Clonality | Polyclonal |
| Clone Number | - |
| Conjugation | Unconjugated |
FAM86A is a class I lysine methyltransferase (KMT), belonging to the family of protein methyltransferases (KMTs), which produces trimethylation (K525me3) at the Lys525 site of eukaryotic translation elongation factor 2 (EEF2) and promotes the binding of eEF2 to ribosomes, thereby regulating the protein synthesis. (PMID: 38508183) FAM86A is expressed in a highly dependent manner in a variety of human cancer cell lines, suggesting that FAM86A may be a potential target for future anticancer therapy. Protocols Product Specific Protocols WB protocol for FAM86A antibody 32472-1-AP Download protocol Standard Protocols Click here to view our Standard Protocols
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