FCRL1 Recombinant monoclonal antibody 86885-1-RR proteintech
$149.00
In stock
SKU
86885-1-RR
| Catalog Number | 86885-1-RR |
| Synonyms | CD307a, Fc receptor-like protein 1, FcRH1, FcR-like protein 1, IFGP family protein 1 |
| Host | Rabbit |
| Reactivity | human |
| Form | Liquid |
| Formulation | PBS, Azide, Glycerol |
| Applications | WB, ELISA |
| Host / Isotype | Rabbit / IgG |
| Tested Applications — Positive WB detected in | Transfected with Human FCRL1 (CD307a) CHO cells |
| Recommended Dilutions — Western Blot (WB) | WB : 1:1000-1:4000 |
| Positive WB detected in | Transfected with Human FCRL1 (CD307a) CHO cells |
| Western Blot (WB) | WB : 1:1000-1:4000 |
| Tested Reactivity | human |
| Class | Recombinant |
| Type | Antibody |
| Immunogen | CatNo: Eg3713 Product name: Recombinant Human FCRL1 protein (rFc Tag) Source: mammalian cells -derived, pHZ-KIsec-C-rFc Tag: C-rFc Domain: 17-307 aa of BC033690 Sequence: AELFLIASPSHPTEGSPVTLTCKMPFLQSSDAQFQFCFFRDTRALGPGWSSSPKLQIAAMWKEDTGSYWCEAQTMASKVLRSRRSQINVHRVPVADVSLETQPPGGQVMEGDRLVLICSVAMGTGDITFLWYKGAVGLNLQSKTQRSLTAEYEIPSVRESDAEQYYCVAENGYGPSPSGLVSITVRIPVSRPILMLRAPRAQAAVEDVLELHCEALRGSPPILYWFYHEDITLGSRSAPSGGGASFNLSLTEEHSGNYSCEANNGLGAQRSEAVTLNFTVPTGARSNHLTS Predict reactive species |
| Full Name | Fc receptor-like 1 |
| Calculated Molecular Weight | 429 aa, 47 kDa |
| Observed Molecular Weight | 75 kDa |
| GenBank Accession Number | BC033690 |
| Gene Symbol | FCRL1 |
| Gene ID (NCBI) | 115350 |
| RRID | AB_3745186 |
| Conjugate | Unconjugated |
| Purification Method | Protein A purification |
| UNIPROT ID | Q96LA6 |
| Storage Buffer | PBS with 0.02% sodium azide and 50% glycerol, pH 7.3. |
| Storage Conditions | Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20 o C storage. 20ul sizes contain 0.1% BSA. |
| WB protocol for FCRL1 antibody 86885-1-RR | Download protocol |
| Citations | - |
| Dilutions | WB : 1:1000-1:4000 |
| Isotype | IgG |
| Clonality | Recombinant |
| Clone Number | 251080E10 |
| Conjugation | Unconjugated |
Fc receptor-like protein 1 (FCRL1) is a type I transmembrane glycoprotein that plays a crucial role in regulating B-cell receptor (BCR)-mediated signaling responses (PMID:15479727). It contains intracellular tyrosine-based motifs that can modulate BCR signaling, leading to changes in calcium flux, proliferation, and antibody production (PMID: 37822931). FCRL1 is involved in regulating B-cell development and activation, with its signaling pathways influencing ERK activation through interactions with proteins such as GRB2. This regulation is essential for maintaining B-cell homeostasis and preventing the development of autoreactive B cells (PMID: 34697226). Since the recombinant protein carries a C-rFc tag, the Western blot result shows a band around 75 kDa. The 60 kDa band is a degradation band. Protocols Product Specific Protocols WB protocol for FCRL1 antibody 86885-1-RR Download protocol Standard Protocols Click here to view our Standard Protocols
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