OMA1 Monoclonal antibody 67449-1-Ig proteintech
$149.00
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SKU
67449-1-Ig
| Catalog Number | 67449-1-Ig |
| Synonyms | 1H4D12, EC:3.4.24.-, Metalloprotease-related protein 1, MPRP1, MPRP-1 |
| Host | Mouse |
| Reactivity | human, mouse |
| Form | Liquid |
| Formulation | PBS, Azide, Glycerol |
| Applications | WB, ELISA |
| Host / Isotype | Mouse / IgG1 |
| Tested Applications — Positive WB detected in | NIH/3T3 cells, HeLa cells, Jurkat cells, LNCaP cells, HEK-293 cells |
| Recommended Dilutions — Western Blot (WB) | WB : 1:1000-1:5000 |
| Positive WB detected in | NIH/3T3 cells, HeLa cells, Jurkat cells, LNCaP cells, HEK-293 cells |
| Western Blot (WB) | WB : 1:1000-1:5000 |
| Tested Reactivity | human, mouse |
| Cited Reactivity | human |
| Class | Monoclonal |
| Type | Antibody |
| Immunogen | CatNo: Ag11201 Product name: Recombinant human OMA1 protein Source: e coli. -derived, PET28a Tag: 6*His Domain: 361-524 aa of BC012915 Sequence: ICPRDSLALLCQWIQSKLQEYMFNRPYSRKLEAEADKIGLLLAAKACADIRASSVFWQQMEFVDSLHGQPKMPEWLSTHPSHGNRVEYLDRLIPQALKIREMCNCPPLSNPDPRLLFKLSTKHFLEESEKEDLNITKKQKMDTLPIQKQEQIPLTYIVEKRTGS Predict reactive species |
| Full Name | OMA1 homolog, zinc metallopeptidase (S. cerevisiae) |
| Calculated Molecular Weight | 524 aa, 60 kDa |
| Observed Molecular Weight | 60 kDa |
| GenBank Accession Number | BC012915 |
| Gene Symbol | OMA1 |
| Gene ID (NCBI) | 115209 |
| RRID | AB_2882683 |
| Conjugate | Unconjugated |
| Purification Method | Protein G purification |
| UNIPROT ID | Q96E52 |
| Storage Buffer | PBS with 0.02% sodium azide and 50% glycerol, pH 7.3. |
| Storage Conditions | Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20 o C storage. 20ul sizes contain 0.1% BSA. |
| WB protocol for OMA1 antibody 67449-1-Ig | Download protocol |
| human | WB Methods Enzymol Monitoring retro-translocation of proteins from the mitochondrial intermembrane space Authors - Magda Krakowczyk View Article |
| Citations | 2 |
| Dilutions | WB : 1:1000-1:5000 |
| Isotype | IgG1 |
| Clonality | Monoclonal |
| Clone Number | 1H4D12 |
| Conjugation | Unconjugated |
OMA1(Overlapping with the m-AAA protease 1 homolog) is also named as MPRP1(Metalloprotease-related protein 1) and belongs to the peptidase M48 family.It is a zinc metalloprotease that spans the inner mitochondrial membrane with a number of predicted membrane spanning domains and the 60 kDa form of OMA1 rapidly accumulated concomitantly with the cleavage of all OPA1 variants,and the 40 kDa form of OMA1 may be the inactive form, with the 60 kDa form being the active enzyme(PMID:20334834) Protocols Product Specific Protocols WB protocol for OMA1 antibody 67449-1-Ig Download protocol Standard Protocols Click here to view our Standard Protocols
Publications
- Parental Alcohol Exposures Associate with Lasting Mitochondrial Dysfunction and Accelerated Aging in a Mouse Model
Journal: Aging Dis | Authors: Alison Basel | Application: WB - Monitoring retro-translocation of proteins from the mitochondrial intermembrane space
Journal: Methods Enzymol | Authors: Magda Krakowczyk | Species: human | Application: WB
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