FMO5 Polyclonal antibody 13699-1-AP proteintech
$149.00
In stock
SKU
13699-1-AP
| Catalog Number | 13699-1-AP |
| Synonyms | Baeyer-Villiger monooxygenase 1, Dimethylaniline monooxygenase [N-oxide-forming] 5, EC:1.14.13.-, EC:1.14.13.8, EC:1.6.3.1 |
| Host | Rabbit |
| Reactivity | human, mouse |
| Form | Liquid |
| Formulation | PBS, Azide, Glycerol |
| Applications | WB, IP, ELISA |
| Host / Isotype | Rabbit / IgG |
| Tested Applications — Positive WB detected in | human liver tissue, mouse lung tissue |
| Tested Applications — Positive IP detected in | mouse lung tissue |
| Recommended Dilutions — Western Blot (WB) | WB : 1:500-1:2400 |
| Recommended Dilutions — Immunoprecipitation (IP) | IP : 0.5-4.0 ug for 1.0-3.0 mg of total protein lysate |
| Positive WB detected in | human liver tissue, mouse lung tissue |
| Positive IP detected in | mouse lung tissue |
| Western Blot (WB) | WB : 1:500-1:2400 |
| Immunoprecipitation (IP) | IP : 0.5-4.0 ug for 1.0-3.0 mg of total protein lysate |
| Tested Reactivity | human, mouse |
| Cited Reactivity | human, mouse |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | CatNo: Ag4604 Product name: Recombinant human FMO5 protein Source: e coli. -derived, T-HIS Tag: 6*His Domain: 34-285 aa of BC035687 Sequence: RTDDIGGLWRFQENPEEGRASIYKSVIINTSKEMMCFSDYPIPDHYPNFMHNAQVLEYFRMYAKEFDLLKYIRFKTTVCSVKKQPDFATSGQWEVVTESEGKKEMNVFDGVMVCTGHHTNAHLPLESFPGIEKFKGQYFHSRDYKNPEGFTGKRVIIIGIGNSGGDLAVEISQTAKQVFLSTRRGAWILNRVGDYGYPADVLFSSRLTHFIWKICGQSLANKYLEKKINQRFDHEMFGLKPKHRSKDIALTE Predict reactive species |
| Full Name | flavin containing monooxygenase 5 |
| Calculated Molecular Weight | 533 aa, 60 kDa |
| Observed Molecular Weight | 60 kDa |
| GenBank Accession Number | BC035687 |
| Gene Symbol | FMO5 |
| Gene ID (NCBI) | 2330 |
| RRID | AB_2105409 |
| Conjugate | Unconjugated |
| Purification Method | Antigen affinity purification |
| UNIPROT ID | P49326 |
| Storage Buffer | PBS with 0.02% sodium azide and 50% glycerol, pH 7.3. |
| Storage Conditions | Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20 o C storage. 20ul sizes contain 0.1% BSA. |
| IP protocol for FMO5 antibody 13699-1-AP | Download protocol |
| WB protocol for FMO5 antibody 13699-1-AP | Download protocol |
| human | WB Cell Metab Endometrial stromal cell-derived TMAO sustains decidualization to prevent recurrent spontaneous abortion. Authors - Yu-Ling Chen View Article |
| mouse | WB Front Pharmacol Puerarin ameliorates non-alcoholic fatty liver disease by inhibiting lipid metabolism through FMO5 Authors - Zhaoyi Li View Article |
| Citations | 6 |
| Dilutions | WB : 1:500-1:2400 IP : 0.5-4.0 ug for IP and 0.5-4.0 ug for 1.0-3.0 mg of total protein lysate for WB |
| Isotype | IgG |
| Clonality | Polyclonal |
| Clone Number | - |
| Conjugation | Unconjugated |
Microsomal flavin-containing monooxygenases (FMOs) [dimethylaniline monooxygenase (N-oxide forming) catalyze the FAD-, NADPH- and O2-dependent oxidation of a large number of structurally diverse compounds, including drugs, pesticides, and industrial chemicals containing a soft nucleophile(PMID:12488558 ). FMO5, which belongs to the FMO family, is a lesser component of human liver microsomes and is present at about one-third the level of FMO3. FMO5 protein is also present at very low levels in kidney, however, FMO5 exhibits a severely restricted substrate specificity for most drugs and other xenobiotics examined to date(PMID:10950857). It has 2 isoforms produced by alternative splicing. Protocols Product Specific Protocols IP protocol for FMO5 antibody 13699-1-AP Download protocol WB protocol for FMO5 antibody 13699-1-AP Download protocol Standard Protocols Click here to view our Standard Protocols
Publications
- Flavin-Containing Monooxygenases Are Conserved Regulators of Stress Resistance and Metabolism.
Journal: Front Cell Dev Biol | Authors: Shijiao Huang | Species: human | Application: WB - The phenotype of a knockout mouse identifies flavin-containing monooxygenase 5 (FMO5) as a regulator of metabolic ageing.
Journal: Biochem Pharmacol | Authors: Sandra G Gonzalez Malagon KO Validated | Species: mouse | Application: WB - The Molecular Mechanism Regulating Diurnal Rhythm of Flavin-Containing Monooxygenase 5 in Mouse Liver.
Journal: Drug Metab Dispos | Authors: Min Chen | Species: mouse | Application: WB - Puerarin ameliorates non-alcoholic fatty liver disease by inhibiting lipid metabolism through FMO5
Journal: Front Pharmacol | Authors: Zhaoyi Li | Species: mouse | Application: WB - Endometrial stromal cell-derived TMAO sustains decidualization to prevent recurrent spontaneous abortion.
Journal: Cell Metab | Authors: Yu-Ling Chen | Species: human | Application: WB - Ceria nanoparticles guard against glucocorticoid induced bone homeostasis imbalance through the promotion of osteogenesis and inhibition of osteoclastogenesis
Journal: Mater Today Bio | Authors: Anwei Zhang
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