Anti-Human CD3 (SK7) 65148-1-Ig proteintech
$49.00
In stock
SKU
65148-1-Ig
| Catalog Number | 65148-1-Ig |
| Synonyms | CD3E, CD3 epsilon, T-cell surface antigen T3/Leu-4 epsilon chain, T3E, SK7 |
| Host | Mouse |
| Reactivity | human |
| Form | Liquid |
| Formulation | PBS, Azide |
| Applications | FC |
| Host / Isotype | Mouse / IgG1, kappa |
| Tested Applications — Positive FC detected in | human PBMCs |
| Positive FC detected in | human PBMCs |
| Flow Cytometry (FC) | FC : 0.2 ug per 10^6 cells in 100 μl suspension |
| Tested Reactivity | human |
| Cited Reactivity | human |
| Class | Monoclonal |
| Type | Antibody |
| Immunogen | N/A Predict reactive species |
| Full Name | CD3e molecule, epsilon (CD3-TCR complex) |
| Calculated Molecular Weight | 207 aa, 23 kDa |
| GenBank Accession Number | BC049847 |
| Gene Symbol | CD3 |
| Gene ID (NCBI) | 916 |
| ENSEMBL Gene ID | ENSG00000198851 |
| RRID | AB_2918433 |
| Conjugate | Unconjugated |
| Purification Method | Protein G purification |
| UNIPROT ID | P07766 |
| Storage Buffer | PBS with 0.09% sodium azide, pH 7.3. |
| Storage Conditions | Store at 2-8°C. Stable for one year after shipment. |
| FC protocol for CD3 antibody 65148-1-Ig | Download protocol |
| human | FC Biochem Biophys Rep Evaluation of an anti-CD3 VHH and construction of an anti-CD3/anti-EGFR bispecific tandem VHH as a cancer cell targeting drug construct Authors - Takuya Asanuma View Article |
| Citations | 1 |
| Isotype | IgG1, kappa |
| Clonality | Monoclonal |
| Clone Number | SK7 |
| Conjugation | Unconjugated |
CD3 is a multimeric protein associated with the T-cell receptor (TCR) to form a complex involved in antigen recognition and signal transduction (PMID: 15885124). CD3 is composed of CD3γ, δ, ε, and ζ chains (PMID: 1826255). It is expressed by thymocytes in a developmentally regulated manner, T cells, and some NK cells (PMID: 3289580). The TCR recognizes antigens bound to major histocompatibility complex (MHC) molecules. TCR-mediated peptide-MHC recognition is transmitted to the CD3 complex, leading to the intracellular signal transduction (PMID: 11985657). Protocols Product Specific Protocols FC protocol for CD3 antibody 65148-1-Ig Download protocol Standard Protocols Click here to view our Standard Protocols
Publications
- Evaluation of an anti-CD3 VHH and construction of an anti-CD3/anti-EGFR bispecific tandem VHH as a cancer cell targeting drug construct
Journal: Biochem Biophys Rep | Authors: Takuya Asanuma | Species: human | Application: FC
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