CoraLite® Plus 488 Anti-Mouse Foxp3 (3G3) CL488-65089 proteintech
$222.00
In stock
SKU
CL488-65089
| Catalog Number | CL488-65089 |
| Synonyms | forkhead box P3, Foxp3, JM2, scurfin, sf |
| Host | Mouse |
| Reactivity | Mouse and More (1) |
| Reactivity | mouse |
| Form | Liquid |
| Formulation | PBS, Azide, BSA |
| Applications | FC (Intra) |
| Host / Isotype | Mouse / IgG1, kappa |
| Tested Applications — Positive FC (Intra) detected in | mouse splenocytes |
| Tested Applications — Positive FC detected in | mouse splenocytes |
| Recommended Dilutions — Flow Cytometry (FC) (INTRA) | FC (INTRA) : 0.06 ug per 10^6 cells in 100 μl suspension |
| Positive FC (Intra) detected in | mouse splenocytes |
| Positive FC detected in | mouse splenocytes |
| Flow Cytometry (FC) (INTRA) | FC (INTRA) : 0.06 ug per 10^6 cells in 100 μl suspension |
| Flow Cytometry (FC) | FC : |
| Tested Reactivity | Mouse |
| Cited Reactivity | mouse |
| Class | Monoclonal |
| Type | Antibody |
| Immunogen | N/A Predict reactive species |
| Full Name | forkhead box P3 |
| GenBank Accession Number | BC132333 |
| Gene Symbol | Foxp3 |
| Gene ID (NCBI) | 20371 |
| RRID | AB_2919258 |
| Conjugate | CoraLite® Plus 488 Fluorescent Dye |
| Excitation/Emission Maxima Wavelengths | 493 nm / 522 nm |
| Excitation Laser | Blue laser (488 nm) |
| Purification Method | Affinity purification |
| UNIPROT ID | Q99JB6 |
| Storage Buffer | PBS with 0.09% sodium azide and 0.5% BSA, pH 7.3. |
| Storage Conditions | Store at 2-8°C. Avoid exposure to light. Stable for one year after shipment. |
| FC protocol for CL Plus 488 Foxp3 antibody CL488-65089 | Download protocol |
| mouse | FC (Intra) Adv Sci (Weinh) Cancer-Associated Fibroblast-Induced Remodeling of Tumor Microenvironment in Recurrent Bladder Cancer Authors - Ting Liang View Article |
| Citations | 1 |
| Dilutions | FC (INTRA) : 0.06 ug per 10^6 cells in 100 μl suspension |
| Isotype | IgG1, kappa |
| Clonality | Monoclonal |
| Clone Number | 3G3 |
| Conjugation | CoraLite® Plus 488 |
Foxp3 (forkhead box P3), also named as IPEX, JM2 and scurfin, is a member of the forkhead transcription factor family and is essential for normal immune homeostasis (PMID: 11138001; 20429413). Foxp3 is specifically expressed in CD4+ CD25+ regulatory T cells and is crucial for their development and suppressive activity (PMID: 12612578; 12612581). In scurfy mouse, disruption of Foxp3 results in the fatal lymphoproliferative disorder attributed to the lack of an immune-suppressive component in the immune system (PMID: 25683611; 11138001). Similar to mice, genetic defects in human Foxp3 are the cause of immunodeficiency polyendocrinopathy, enteropathy, X-linked syndrome (IPEX) which also known as X-linked autoimmunity-immunodeficiency syndrome (PMID: 11137993). Protocols Product Specific Protocols FC protocol for CL Plus 488 Foxp3 antibody CL488-65089 Download protocol Standard Protocols Click here to view our Standard Protocols
Publications
- Cancer-Associated Fibroblast-Induced Remodeling of Tumor Microenvironment in Recurrent Bladder Cancer
Journal: Adv Sci (Weinh) | Authors: Ting Liang | Species: mouse | Application: FC (Intra)
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