PE Anti-Mouse Foxp3 (3G3) PE-65089 proteintech
$215.00
In stock
SKU
PE-65089
| Catalog Number | PE-65089 |
| Synonyms | 3G3, forkhead box P3, Forkhead box protein P3 41 kDa form, Forkhead box protein P3, C-terminally processed, JM2 |
| Host | Mouse |
| Reactivity | mouse and More (1) |
| Reactivity | mouse, rat |
| Form | Liquid |
| Formulation | PBS, Azide, BSA |
| Applications | FC (Intra) |
| Host / Isotype | Mouse / IgG1, kappa |
| Tested Applications — Positive FC (Intra) detected in | mouse splenocytes |
| Recommended Dilutions — Flow Cytometry (FC) (INTRA) | FC (INTRA) : 0.06 ug per 10^6 cells in a 100 µl suspension |
| Positive FC (Intra) detected in | mouse splenocytes |
| Flow Cytometry (FC) (INTRA) | FC (INTRA) : 0.06 ug per 10^6 cells in a 100 µl suspension |
| Tested Reactivity | mouse |
| Cited Reactivity | mouse, rat |
| Class | Monoclonal |
| Type | Antibody |
| Immunogen | N/A Predict reactive species |
| Full Name | forkhead box P3 |
| GenBank Accession Number | BC132333 |
| Gene Symbol | Foxp3 |
| Gene ID (NCBI) | 20371 |
| RRID | AB_2883883 |
| Conjugate | PE Fluorescent Dye |
| Excitation/Emission Maxima Wavelengths | 496 nm, 565 nm / 578 nm |
| Excitation Laser | Blue Laser (488 nm), Green Laser (532 nm), Yellow-Green Laser (561 nm) |
| Purification Method | Affinity purification |
| UNIPROT ID | Q99JB6 |
| Storage Buffer | PBS with 0.09% sodium azide and 0.5% BSA, pH 7.3. |
| Storage Conditions | Store at 2-8°C. Avoid exposure to light. Stable for one year after shipment. |
| FC protocol for PE Foxp3 antibody PE-65089 | Download protocol |
| mouse | FC (Intra) Hum Cell Tetramerization of pyruvate kinase M2 attenuates graft-versus-host disease by inhibition of Th1 and Th17 differentiation Authors - Meng Wang View Article |
| Citations | 10 |
| Dilutions | FC (INTRA) : 0.06 ug per 10^6 cells in a 100 µl suspension |
| Isotype | IgG1, kappa |
| Clonality | Monoclonal |
| Clone Number | 3G3 |
| Conjugation | PE |
Foxp3 (forkhead box P3), also named as IPEX, JM2 and scurfin, is a member of the forkhead transcription factor family and is essential for normal immune homeostasis (PMID: 11138001; 20429413). Foxp3 is specifically expressed in CD4+ CD25+ regulatory T cells and is crucial for their development and suppressive activity (PMID: 12612578; 12612581). In scurfy mouse, disruption of Foxp3 results in the fatal lymphoproliferative disorder attributed to the lack of an immune-suppressive component in the immune system (PMID: 25683611; 11138001). Similar to mice, genetic defects in human Foxp3 are the cause of immunodeficiency polyendocrinopathy, enteropathy, X-linked syndrome (IPEX) which also known as X-linked autoimmunity-immunodeficiency syndrome (PMID: 11137993). Protocols Product Specific Protocols FC protocol for PE Foxp3 antibody PE-65089 Download protocol Standard Protocols Click here to view our Standard Protocols
Publications
- Multi-material basis and multi-mechanisms of the Dahuang Zhechong pill for regulating Treg/Th1 balance in hepatocellular carcinoma.
Journal: Phytomedicine | Authors: Li Wu | Species: mouse | Application: FC (Intra) - Neutrophil extracellular traps aggravate periodontitis by disturbing regulatory T-cell differentiation
Journal: Genes Immun | Authors: Beibei Chen - Podocyte SIRPα reduction aggravates lupus nephritis via promoting T cell inflammatory responses
Journal: Cell Rep | Authors: Bin Qian - Nano co-inducer of immunogenic cell death and ferroptosis for anti-tumor immunotherapy
Journal: J Colloid Interface Sci | Authors: Guanhong Guo | Species: mouse | Application: FC - Design of a targeted dual drug delivery system for boosting the efficacy of photoimmunotherapy against melanoma proliferation and metastasis
Journal: J Adv Res | Authors: Yi Chen | Species: mouse | Application: FC - Tetramerization of pyruvate kinase M2 attenuates graft-versus-host disease by inhibition of Th1 and Th17 differentiation
Journal: Hum Cell | Authors: Meng Wang | Species: mouse | Application: FC (Intra) - Podocyte SIRPα reduction aggravates lupus nephritis via promoting T cell inflammatory responses
Journal: Cell Rep | Authors: Bin Qian - Chlorogenic acid mitigates acute respiratory distress syndrome via inhibition of the PI3K/AKT signalling pathway: an integrated analysis of bioinformatics and validation experiments.
Journal: Ann Med | Authors: Jie Wei | Species: rat | Application: FC - Neutrophil extracellular traps aggravate periodontitis by disturbing regulatory T-cell differentiation
Journal: Genes Immun | Authors: Beibei Chen - Tetramerization of pyruvate kinase M2 attenuates graft-versus-host disease by inhibition of Th1 and Th17 differentiation
Journal: Hum Cell | Authors: Meng Wang | Species: mouse | Application: FC (Intra)
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