GABA B receptor 1 Polyclonal antibody 13940-1-AP proteintech
$149.00
In stock
SKU
13940-1-AP
| Catalog Number | 13940-1-AP |
| Synonyms | GABAB receptor 1, GABBR1, GABA B R1, GABA BR1, GABA-B receptor 1 |
| Host | Rabbit |
| Reactivity | human, mouse, rat |
| Form | Liquid |
| Formulation | PBS, Azide, Glycerol |
| Applications | WB, IHC, ELISA |
| Host / Isotype | Rabbit / IgG |
| Tested Applications — Positive WB detected in | mouse brain tissue, 37°C incubated mouse brain tissue, rat brain tissue, 37°C incubated rat brain tissue |
| Tested Applications — Positive IHC detected in | mouse brain tissue, rat brain tissue Note: suggested antigen retrieval with TE buffer pH 9.0; (*) Alternatively, antigen retrieval may be performed with citrate buffer pH 6.0 |
| Recommended Dilutions — Western Blot (WB) | WB : 1:500-1:2000 |
| Recommended Dilutions — Immunohistochemistry (IHC) | IHC : 1:50-1:500 |
| Positive WB detected in | mouse brain tissue, 37°C incubated mouse brain tissue, rat brain tissue, 37°C incubated rat brain tissue |
| Positive IHC detected in | mouse brain tissue, rat brain tissue Note: suggested antigen retrieval with TE buffer pH 9.0; (*) Alternatively, antigen retrieval may be performed with citrate buffer pH 6.0 |
| Western Blot (WB) | WB : 1:500-1:2000 |
| Immunohistochemistry (IHC) | IHC : 1:50-1:500 |
| Tested Reactivity | human, mouse, rat |
| Cited Reactivity | human, mouse |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | CatNo: Ag4838 Product name: Recombinant human GABBR1 protein Source: e coli. -derived, PGEX-4T Tag: GST Domain: 101-471 aa of BC041332 Sequence: SKCDPGQATKYLYELLYNDPIKIILMPGCSSVSTLVAEAARMWNLIVLSYGSSSPALSNRQRFPTFFRTHPSATLHNPTRVKLFEKWGWKKIATIQQTTEVFTSTLDDLEERVKEAGIEITFRQSFFSDPAVPVKNLKRQDARIIVGLFYETEARKVFCEVYKERLFGKKYVWFLIGWYADNWFKIYDPSINCTVDEMTEAVEGHITTEIVMLNPANTRSISNMTSQEFVEKLTKRLKRHPEETGGFQEAPLAYDAIWALALALNKTSGGGGRSGVRLEDFNYNNQTITDQIYRAMNSSSFEGVSGHVVFDASGSRMAWTLIEQLQGGSYKKIGYYDSTKDDLSWSKTDKWIGGSPPADQTLVIKTFRFLS Predict reactive species |
| Full Name | gamma-aminobutyric acid (GABA) B receptor, 1 |
| Calculated Molecular Weight | 961 aa, 108 kDa |
| Observed Molecular Weight | 105-130 kDa |
| GenBank Accession Number | BC041332 |
| Gene Symbol | GABBR1 |
| Gene ID (NCBI) | 2550 |
| RRID | AB_2108159 |
| Conjugate | Unconjugated |
| Purification Method | Antigen affinity purification |
| UNIPROT ID | Q9UBS5 |
| Storage Buffer | PBS with 0.02% sodium azide and 50% glycerol, pH 7.3. |
| Storage Conditions | Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20 o C storage. 20ul sizes contain 0.1% BSA. |
| IHC protocol for GABA B receptor 1 antibody 13940-1-AP | Download protocol |
| WB protocol for GABA B receptor 1 antibody 13940-1-AP | Download protocol |
| human | WB Biochem Biophys Res Commun AJAP1 affects behavioral changes and GABABR1 level in epileptic mice. Authors - Mingli Zhang View Article |
| mouse | WB Brain Behav Immun Targeted fecal microbiota transplantation ameliorates autism-like behaviors via gut-brain axis and excitatory/inhibitory balance restoration in a propionic acid mouse model. Authors - Jianquan He View Article |
| Citations | 3 |
| Dilutions | WB : 1:500-1:2000 IHC : 1:50-1:500 |
| Isotype | IgG |
| Clonality | Polyclonal |
| Clone Number | - |
| Conjugation | Unconjugated |
GABA B receptor 1 (GABBR1) is an essential protein subunit that forms the functional GABA B receptor, a metabotropic receptor for the primary inhibitory neurotransmitter in the central nervous system, gamma-aminobutyric acid (GABA). Unlike the fast-acting ionotropic GABA A receptors, GABA B receptors mediate slow, prolonged inhibitory signaling through G-proteins. Two bands with the apparent molecular weights of 130 and 105 kDa were corresponding to GABAB1a and GABAB1b proteins, were identified in the brain extract and membrane extract of wild-type mice (PMID: 12970075). Protocols Product Specific Protocols IHC protocol for GABA B receptor 1 antibody 13940-1-AP Download protocol WB protocol for GABA B receptor 1 antibody 13940-1-AP Download protocol Standard Protocols Click here to view our Standard Protocols
Publications
- AJAP1 affects behavioral changes and GABABR1 level in epileptic mice.
Journal: Biochem Biophys Res Commun | Authors: Mingli Zhang | Species: human | Application: WB - Cu(OH)(2) nanopesticide induced adolescent social behavior deficits via long noncoding RNA-mediated synaptic network dysfunction.
Journal: J Hazard Mater | Authors: Zhihua Ren | Species: mouse | Application: WB - Targeted fecal microbiota transplantation ameliorates autism-like behaviors via gut-brain axis and excitatory/inhibitory balance restoration in a propionic acid mouse model.
Journal: Brain Behav Immun | Authors: Jianquan He | Species: mouse | Application: WB
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