Centrin 1 Monoclonal antibody 68433-1-Ig proteintech
$149.00
In stock
SKU
68433-1-Ig
| Catalog Number | 68433-1-Ig |
| Synonyms | Caltractin isoform 2, CEN1, Centrin 1, centrin, EF hand protein, 1, CETN, CETN1 |
| Host | Mouse |
| Reactivity | Human and More (1) |
| Reactivity | human |
| Form | Liquid |
| Formulation | PBS, Azide, Glycerol |
| Applications | IF/ICC, ELISA |
| Host / Isotype | Mouse / IgG2b |
| Tested Applications — Positive IF/ICC detected in | hTERT-RPE1 cells, ARPE-19 cells |
| Recommended Dilutions — Immunofluorescence (IF)/ICC | IF/ICC : 1:250-1:1000 |
| Positive IF/ICC detected in | hTERT-RPE1 cells, ARPE-19 cells |
| Immunofluorescence (IF)/ICC | IF/ICC : 1:250-1:1000 |
| Tested Reactivity | Human |
| Cited Reactivity | human |
| Class | Monoclonal |
| Type | Antibody |
| Immunogen | CatNo: Ag3529 Product name: Recombinant human CETN1 protein Source: e coli. -derived, PGEX-4T Tag: GST Domain: 1-172 aa of BC029515 Sequence: MASGFKKPSAASTGQKRKVAPKPELTEDQKQEVREAFDLFDVDGSGTIDAKELKVAMRALGFEPRKEEMKKMISEVDREGTGKISFNDFLAVMTQKMSEKDTKEEILKAFRLFDDDETGKISFKNLKRVANELGENLTDEELQEMIDEADRDGDGEVNEEEFLRIMKKTSLY Predict reactive species |
| Full Name | centrin, EF-hand protein, 1 |
| Calculated Molecular Weight | 172 aa, 20 kDa |
| Observed Molecular Weight | 20 kDa |
| GenBank Accession Number | BC029515 |
| Gene Symbol | Centrin 1 |
| Gene ID (NCBI) | 1068 |
| RRID | AB_3085147 |
| Conjugate | Unconjugated |
| Purification Method | Protein A purification |
| UNIPROT ID | Q12798 |
| Storage Buffer | PBS with 0.02% sodium azide and 50% glycerol, pH 7.3. |
| Storage Conditions | Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20 o C storage. 20ul sizes contain 0.1% BSA. |
| IF protocol for Centrin 1 antibody 68433-1-Ig | Download protocol |
| human | IF Oncogene LIMK2 promotes centrosome clustering and cancer progression by activating MST4-mediated phosphorylation of NPM1 Authors - Jie Tian View Article |
| Citations | 1 |
| Dilutions | IF/ICC : 1:250-1:1000 |
| Isotype | IgG2b |
| Clonality | Monoclonal |
| Clone Number | 1G8D10 |
| Conjugation | Unconjugated |
EF-hand type Ca2+-binding proteins consists of several family members, including Centrin-1, Centrin-2 and Centrin-3. The Centrin proteins are ubiquitously expressed cytoskeletal components that show increased expression during cell differentiation. Centrin-1 plays important roles in the determination of centrosome position and segregation, and in the process of microtubule severing. Centrin-1 is localized to the centrosome of interphase cells, and redistributes to the region of the spindle poles during mitosis, reflecting the dynamic behavior of the centrosome during the cell cycle. Protocols Product Specific Protocols IF protocol for Centrin 1 antibody 68433-1-Ig Download protocol Standard Protocols Click here to view our Standard Protocols
Publications
- LIMK2 promotes centrosome clustering and cancer progression by activating MST4-mediated phosphorylation of NPM1
Journal: Oncogene | Authors: Jie Tian | Species: human | Application: IF
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