GBP1 Monoclonal antibody, PBS Only 67161-1-PBS proteintech
$699.00
In stock
SKU
67161-1-PBS
| Catalog Number | 67161-1-PBS |
| Synonyms | Guanine nucleotide-binding protein 1, GTP-binding protein 1, GBP-1, GBP 1, EC:3.6.1.- |
| Host | Mouse |
| Reactivity | human, rat, pig |
| Form | Liquid |
| Formulation | PBS Only |
| Applications | WB, IHC, Indirect ELISA |
| Host / Isotype | Mouse / IgG2b |
| Tested Reactivity | human, rat, pig |
| Class | Monoclonal |
| Type | Antibody |
| Immunogen | CatNo: Ag7767 Product name: Recombinant human GBP1 protein Source: e coli. -derived, PET28a Tag: 6*His Domain: 242-592 aa of BC002666 Sequence: VHRRKLAQLEKLQDEELDPEFVQQVADFCSYIFSNSKTKTLSGGIQVNGPRLESLVLTYVNAISSGDLPCMENAVLALAQIENSAAVQKAIAHYEQQMGQKVQLPTESLQELLDLHRDSEREAIEVFIRSSFKDVDHLFQKELAAQLEKKRDDFCKQNQEASSDRCSGLLQVIFSPLEEEVKAGIYSKPGGYRLFVQKLQDLKKKYYEEPRKGIQAEEILQTYLKSKESMTDAILQTDQTLTEKEKEIEVERVKAESAQASAKMLQEMQRKNEQMMEQKERSYQEHLKQLTEKMENDRVQLLKEQERTLALKLQEQEQLLKEGFQKESRIMKNEIQDLQTKMRRRKACTIS Predict reactive species |
| Full Name | GTP binding protein 1 |
| Calculated Molecular Weight | 68 kDa |
| Observed Molecular Weight | 68 kDa |
| GenBank Accession Number | BC002666 |
| Gene Symbol | GBP1 |
| Gene ID (NCBI) | 2633 |
| RRID | AB_2882457 |
| Conjugate | Unconjugated |
| Purification Method | Protein A purification |
| UNIPROT ID | P32455 |
| Storage Buffer | PBS only, pH 7.3. |
| Storage Conditions | Store at -80°C. |
| Citations | - |
| Isotype | IgG2b |
| Clonality | Monoclonal |
| Clone Number | 2A10E8 |
| Conjugation | Unconjugated |
Guanylate binding protein 1 (GBP1) belongs to the dynamin superfamily of large GTPases. The expression of GBP1 is induced by IFN and GBP1 is characterized by its ability to specifically bind guanine nucleotides such as GMP, GDP, and GTP and its ability to hydrolyze GTP to GDP and GMP. GBP1 is induced in response to type I and type II IFNs and as such plays a role in protective immunity against a spectrum of intracellular pathogens ranging from viruses to bacteria to protozoa, such as negative-strand RNA Rhabdovirus, vesicular stomatitis virus and the positive-strand RNA Picornovirus, encephalomyocarditis virus in cultured cells, the inhibition of Chlamydia trachomatis, Toxoplasma gondii, and Salmonella enterica.
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