GIMAP5 Monoclonal antibody 66943-1-Ig proteintech
$149.00
In stock
SKU
66943-1-Ig
| Catalog Number | 66943-1-Ig |
| Synonyms | 1B6F2, hIAN5, HIMAP3, IAN 5, IAN4 |
| Host | Mouse |
| Reactivity | human |
| Form | Liquid |
| Formulation | PBS, Azide, Glycerol |
| Applications | WB, IHC, ELISA |
| Host / Isotype | Mouse / IgG1 |
| Tested Applications — Positive WB detected in | Jurkat cells |
| Tested Applications — Positive IHC detected in | human lymphoma tissue Note: suggested antigen retrieval with TE buffer pH 9.0; (*) Alternatively, antigen retrieval may be performed with citrate buffer pH 6.0 |
| Recommended Dilutions — Western Blot (WB) | WB : 1:1000-1:6000 |
| Recommended Dilutions — Immunohistochemistry (IHC) | IHC : 1:250-1:1000 |
| Positive WB detected in | Jurkat cells |
| Positive IHC detected in | human lymphoma tissue Note: suggested antigen retrieval with TE buffer pH 9.0; (*) Alternatively, antigen retrieval may be performed with citrate buffer pH 6.0 |
| Western Blot (WB) | WB : 1:1000-1:6000 |
| Immunohistochemistry (IHC) | IHC : 1:250-1:1000 |
| Tested Reactivity | human |
| Class | Monoclonal |
| Type | Antibody |
| Immunogen | CatNo: Ag18045 Product name: Recombinant human GIMAP5 protein Source: e coli. -derived, PET28a Tag: 6*His Domain: 1-307 aa of BC011732 Sequence: MGGFQRGKYGTMAEGRSEDNLSATPPALRIILVGKTGCGKSATGNSILGQPVFESKLRAQSVTRTCQVKTGTWNGRKVLVVDTPSIFESQADTQELYKNIGDCYLLSAPGPHVLLLVIQLGRFTAQDTVAIRKVKEVFGTGAMRHVVILFTHKEDLGGQALDDYVANTDNCSLKDLVRECERRYCAFNNWGSVEEQRQQQAELLAVIERLGREREGSFHSNDLFLDAQLLQRTGAGACQEDYRQYQAKVEWQVEKHKQELRENESNWAYKALLRVKHLMLLHYEIFVFLLLCSILFFIIFLFIFHYI Predict reactive species |
| Full Name | GTPase, IMAP family member 5 |
| Calculated Molecular Weight | 35 kDa |
| Observed Molecular Weight | 30-35 kDa |
| GenBank Accession Number | BC011732 |
| Gene Symbol | GIMAP5 |
| Gene ID (NCBI) | 55340 |
| RRID | AB_2882267 |
| Conjugate | Unconjugated |
| Purification Method | Protein G purification |
| UNIPROT ID | Q96F15 |
| Storage Buffer | PBS with 0.02% sodium azide and 50% glycerol, pH 7.3. |
| Storage Conditions | Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20 o C storage. 20ul sizes contain 0.1% BSA. |
| IHC protocol for GIMAP5 antibody 66943-1-Ig | Download protocol |
| WB protocol for GIMAP5 antibody 66943-1-Ig | Download protocol |
| Citations | - |
| Dilutions | WB : 1:1000-1:6000 IHC : 1:250-1:1000 |
| Isotype | IgG1 |
| Clonality | Monoclonal |
| Clone Number | 1B6F2 |
| Conjugation | Unconjugated |
GIMAP5 gene encodes immunity-associated nucleotide 5 protein (IAN5) belonging to GTPase immune-associated protein subfamily. GIMAP5 is widely expressed with high levels in lymph node and spleen. The loss of Gimap5 (GTPase of the 5) gene function is the underlying cause of lymphopenia and autoimmune diabetes in the BioBreeding (BB) rat. Mouse gimap5 is necessary for the survival of peripheral T cells, NK/NKT-cell development, hematopoietic progenitor cell survival and the maintenance of normal liver function. GIMAP5 may regulate T lymphocyte survival by mechanisms that operate upstream of mitochondria. Protocols Product Specific Protocols IHC protocol for GIMAP5 antibody 66943-1-Ig Download protocol WB protocol for GIMAP5 antibody 66943-1-Ig Download protocol Standard Protocols Click here to view our Standard Protocols
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