GLDC Recombinant monoclonal antibody 86378-1-RR proteintech

$149.00
In stock
SKU
86378-1-RR
Catalog No.SizePrice (USD)
86378-1-RR-20UL20 μL$149.00
86378-1-RR-100UL100 μL$449.00
86378-1-RR-10X100UL1 mL (10 x 100 μL vials)$3,592.00
Catalog Number86378-1-RR
Synonymsaminomethyl-transferring, EC:1.4.4.2, GCE, GCSP, Glycine dehydrogenase
HostRabbit
Reactivityhuman, mouse, rat, monkey
FormLiquid
FormulationPBS, Azide, Glycerol
ApplicationsWB, IHC, ELISA
Host / IsotypeRabbit / IgG
Tested Applications — Positive WB detected inHepG2 cells, Vero cells, mouse liver tissue, rat liver tissue
Tested Applications — Positive IHC detected inhuman liver tissue Note: suggested antigen retrieval with TE buffer pH 9.0; (*) Alternatively, antigen retrieval may be performed with citrate buffer pH 6.0
Recommended Dilutions — Western Blot (WB)WB : 1:5000-1:50000
Recommended Dilutions — Immunohistochemistry (IHC)IHC : 1:500-1:2000
Positive WB detected inHepG2 cells, Vero cells, mouse liver tissue, rat liver tissue
Positive IHC detected inhuman liver tissue Note: suggested antigen retrieval with TE buffer pH 9.0; (*) Alternatively, antigen retrieval may be performed with citrate buffer pH 6.0
Western Blot (WB)WB : 1:5000-1:50000
Immunohistochemistry (IHC)IHC : 1:500-1:2000
Tested Reactivityhuman, mouse, rat, monkey
ClassRecombinant
TypeAntibody
ImmunogenCatNo: Ag20410 Product name: Recombinant human GLDC protein Source: e coli. -derived, PET28a Tag: 6*His Domain: 675-1020 aa of BC111995 Sequence: NIDAVHLKAMVDKHKENLAAIMITYPSTNGVFEENISDVCDLIHQHGGQVYLDGANMNAQVGICRPGDFGSDVSHLNLHKTFCIPHGGGGPGMGPIGVKKHLAPFLPNHPVISLKRNEDACPVGTVSAAPWGSSSILPISWAYIKMMGGKGLKQATETAILNANYMAKRLETHYRILFRGARGYVGHEFILDTRPFKKSANIEAVDVAKRLQDYGFHAPTMSWPVAGTLMVEPTESEDKAELDRFCDAMISIRQEIADIEEGRIDPRVNPLKMSPHSLTCVTSSHWDRPYSREVAAFPLPFVKPENKFWPTIARIDDIYGDQHLVCTCPPMEVYESPFSEQKRASS Predict reactive species
Full Nameglycine dehydrogenase (decarboxylating)
Calculated Molecular Weight1020 aa, 113 kDa
Observed Molecular Weight113 kDa
GenBank Accession NumberBC111995
Gene SymbolGLDC
Gene ID (NCBI)2731
RRIDAB_3744850
ConjugateUnconjugated
Purification MethodProtein A purification
UNIPROT IDP23378
Storage BufferPBS with 0.02% sodium azide and 50% glycerol, pH 7.3.
Storage ConditionsStore at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20 o C storage. 20ul sizes contain 0.1% BSA.
IHC protocol for GLDC antibody 86378-1-RRDownload protocol
WB protocol for GLDC antibody 86378-1-RRDownload protocol
Citations-
DilutionsWB : 1:5000-1:50000 IHC : 1:500-1:2000
IsotypeIgG
ClonalityRecombinant
Clone Number250916A5
ConjugationUnconjugated

GLDC(Glycine dehydrogenase [decarboxylating], mitochondrial) is also named as GCSP and belongs to the GcvP family. It induces dramatic changes in glycolysis and glycine/serine metabolism that leads to changes in pyrimidine metabolism to regulate cancer cell proliferation(PMID:22225612). Protocols Product Specific Protocols IHC protocol for GLDC antibody 86378-1-RR Download protocol WB protocol for GLDC antibody 86378-1-RR Download protocol Standard Protocols Click here to view our Standard Protocols

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