FTCD Monoclonal antibody 66979-1-Ig proteintech
$149.00
In stock
SKU
66979-1-Ig
| Catalog Number | 66979-1-Ig |
| Synonyms | Formimidoyltetrahydrofolate cyclodeaminase, Formimidoyltransferase-cyclodeaminase, Formiminotransferase-cyclodeaminase, Glutamate formimidoyltransferase, Glutamate formiminotransferase |
| Host | Mouse |
| Reactivity | human, mouse, rat, pig |
| Form | Liquid |
| Formulation | PBS, Azide, Glycerol |
| Applications | WB, IHC, IF-P, ELISA |
| Host / Isotype | Mouse / IgG2b |
| Tested Applications — Positive WB detected in | mouse liver tissue, pig kidney tissue, pig liver tissue, rat liver tissue |
| Tested Applications — Positive IHC detected in | human kidney tissue, human liver cancer tissue Note: suggested antigen retrieval with TE buffer pH 9.0; (*) Alternatively, antigen retrieval may be performed with citrate buffer pH 6.0 |
| Tested Applications — Positive IF-P detected in | human liver cancer tissue, mouse kidney tissue |
| Recommended Dilutions — Western Blot (WB) | WB : 1:3000-1:10000 |
| Recommended Dilutions — Immunohistochemistry (IHC) | IHC : 1:150-1:600 |
| Recommended Dilutions — Immunofluorescence (IF)-P | IF-P : 1:200-1:800 |
| Positive WB detected in | mouse liver tissue, pig kidney tissue, pig liver tissue, rat liver tissue |
| Positive IHC detected in | human kidney tissue, human liver cancer tissue Note: suggested antigen retrieval with TE buffer pH 9.0; (*) Alternatively, antigen retrieval may be performed with citrate buffer pH 6.0 |
| Positive IF-P detected in | human liver cancer tissue, mouse kidney tissue |
| Western Blot (WB) | WB : 1:3000-1:10000 |
| Immunohistochemistry (IHC) | IHC : 1:150-1:600 |
| Immunofluorescence (IF)-P | IF-P : 1:200-1:800 |
| Tested Reactivity | human, mouse, rat, pig |
| Cited Reactivity | mouse |
| Class | Monoclonal |
| Type | Antibody |
| Immunogen | CatNo: Ag17429 Product name: Recombinant human FTCD protein Source: e coli. -derived, PET28a Tag: 6*His Domain: 192-541 aa of BC136395 Sequence: TKEQAHRIALNLREQGRGKDQPGRLKKVQGIGWYLDEKNLAQVSTNLLDFEVTALHTVYEETCREAQELSLPVVGSQLVGLVPLKALLDAAAFYCEKENLFILEEEQRIRLVVSRLGLDSLCPFSPKERIIEYLVPERGPERGLGSKSLRAFVGEVGARSAAPGGGSVAAAAAAMGAALGSMVGLMTYGRRQFQSLDTTMRRLIPPFREASAKLTTLVDADAEAFTAYLEAMRLPKNTPEEKDRRTAALQEGLRRAVSVPLTLAETVASLWPALQELARCGNLACRSDLQVAAKALEMGVFGAYFNVLINLRDITDEAFKDQIHHRVSSLLQEAKTQAALVLDCLETRQE Predict reactive species |
| Full Name | formiminotransferase cyclodeaminase |
| Calculated Molecular Weight | 541 aa, 59 kDa |
| Observed Molecular Weight | 53-62 kDa |
| GenBank Accession Number | BC136395 |
| Gene Symbol | FTCD |
| Gene ID (NCBI) | 10841 |
| RRID | AB_2882299 |
| Conjugate | Unconjugated |
| Purification Method | Protein A purification |
| UNIPROT ID | O95954 |
| Storage Buffer | PBS with 0.02% sodium azide and 50% glycerol, pH 7.3. |
| Storage Conditions | Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20 o C storage. 20ul sizes contain 0.1% BSA. |
| IF protocol for FTCD antibody 66979-1-Ig | Download protocol |
| IHC protocol for FTCD antibody 66979-1-Ig | Download protocol |
| WB protocol for FTCD antibody 66979-1-Ig | Download protocol |
| mouse | WB Biomolecules Exosome-Related FTCD Facilitates M1 Macrophage Polarization and Impacts the Prognosis of Hepatocellular Carcinoma Authors - Youyi Liu KD Validated View Article |
| Citations | 1 |
| Dilutions | WB : 1:3000-1:10000 IHC : 1:150-1:600 IF-P : 1:200-1:800 |
| Isotype | IgG2b |
| Clonality | Monoclonal |
| Clone Number | 1H8A1 |
| Conjugation | Unconjugated |
FTCD (formimidoyltransferase cyclodeaminase) is critical for the catabolism of histidine. This process is one-carbon units that can enter the one-carbon/folate cycle, which provides methyl groups for arsenic metabolism (PMID: 30893314). In addition, FTCD could serve as a predictive and prognostic marker for patients with HCC (PMID: 37675273). Protocols Product Specific Protocols IF protocol for FTCD antibody 66979-1-Ig Download protocol IHC protocol for FTCD antibody 66979-1-Ig Download protocol WB protocol for FTCD antibody 66979-1-Ig Download protocol Standard Protocols Click here to view our Standard Protocols
Publications
- Exosome-Related FTCD Facilitates M1 Macrophage Polarization and Impacts the Prognosis of Hepatocellular Carcinoma
Journal: Biomolecules | Authors: Youyi Liu KD Validated | Species: mouse | Application: WB
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