IL-17F Monoclonal antibody 60245-1-Ig proteintech
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SKU
60245-1-Ig
| Catalog Number | 60245-1-Ig |
| Synonyms | IL17F, Cytokine ML 1, Cytokine ML-1, IL 17F, interleukin 17F |
| Host | Mouse |
| Reactivity | human |
| Form | Liquid |
| Formulation | PBS, Azide, Glycerol |
| Applications | WB, IHC, ELISA |
| Applications | WB, ELISA |
| Host / Isotype | Mouse / IgG1 |
| Tested Applications — Positive WB detected in | human brain tissue |
| Recommended Dilutions — Western Blot (WB) | WB : 1:500-1:2000 |
| Positive WB detected in | human brain tissue |
| Western Blot (WB) | WB : 1:500-1:2000 |
| Tested Reactivity | human |
| Cited Reactivity | human |
| Class | Monoclonal |
| Type | Antibody |
| Immunogen | CatNo: Ag16310 Product name: Recombinant human IL-17F protein Source: e coli. -derived, PET28a Tag: 6*His Domain: 1-163 aa of BC070124 Sequence: MTVKTLHGPAMVKYLLLSILGLAFLSEAAARKIPKVGHTFFQKPESCPPVPGGSMKLDIGIINENQRVSMSRNIESRSTSPWNYTVTWDPNRYPSEVVQAQCRNLGCINAQGKEDISMNSVPIQQETLVVRRKHQGCSVSFQLEKVLVTVGCTCVTPVIHRVQ Predict reactive species |
| Full Name | interleukin 17F |
| Calculated Molecular Weight | 163 aa, 18 kDa |
| Observed Molecular Weight | 37 kDa |
| GenBank Accession Number | BC070124 |
| Gene Symbol | IL-17F |
| Gene ID (NCBI) | 112744 |
| RRID | AB_2881367 |
| Conjugate | Unconjugated |
| Purification Method | Protein G purification |
| UNIPROT ID | Q96PD4 |
| Storage Buffer | PBS with 0.02% sodium azide and 50% glycerol, pH 7.3. |
| Storage Conditions | Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20 o C storage. 20ul sizes contain 0.1% BSA. |
| WB protocol for IL-17F antibody 60245-1-Ig | Download protocol |
| human | IHC J Cutan Pathol Pyoderma Gangrenosum Associated With Iatrogenic Interleukin 17A Blockade: A Report of Two Cases and a Review of the Literature Authors - Cynthia M Magro View Article |
| Citations | 1 |
| Dilutions | WB : 1:500-1:2000 |
| Isotype | IgG1 |
| Clonality | Monoclonal |
| Clone Number | 6H5F10 |
| Conjugation | Unconjugated |
The interleukin 17 (IL-17) family of cytokines contains 6 structurally related cytokines, IL-17A, IL-17B, IL-17C, IL-17D, IL-17E and IL-17F. IL-17 family plays crucial roles in host defense against microbial organisms and in the development of inflammatory diseases. IL-17A is a pro-inflammatory cytokine that also has the capacity to promote angiogenesis and osteoclastogenesis. IL-17F shares the highest homology with IL-17A and signals via a receptor composed by the IL-17RA and IL-17RC subunits. IL-17A and IL-17F can form IL-17A/A or IL-17F/F homodimers, IL-17A/F heterodimers are also formed. IL-17A and IL-17F, produced by the Th17 CD4(+) T cell lineage, have been linked to a variety of inflammatory and autoimmune conditions. IL-17F levels are elevated in sera and lesional psoriatic skin compared to non-lesional tissue. IL-17F also has been implicated in the development of neutrophilic airway inflammation. Protocols Product Specific Protocols WB protocol for IL-17F antibody 60245-1-Ig Download protocol Standard Protocols Click here to view our Standard Protocols
Publications
- Pyoderma Gangrenosum Associated With Iatrogenic Interleukin 17A Blockade: A Report of Two Cases and a Review of the Literature
Journal: J Cutan Pathol | Authors: Cynthia M Magro | Species: human | Application: IHC
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