GSDMA Recombinant monoclonal antibody 82920-1-RR proteintech
$149.00
In stock
SKU
82920-1-RR
| Catalog Number | 82920-1-RR |
| Synonyms | Gasdermin-A, Gasdermin-1, gasdermin A, Gasdermin 1, FKSG9 |
| Host | Rabbit |
| Reactivity | human |
| Form | Liquid |
| Formulation | PBS, Azide, Glycerol |
| Applications | WB, ELISA |
| Host / Isotype | Rabbit / IgG |
| Tested Applications — Positive WB detected in | Daudi cells |
| Recommended Dilutions — Western Blot (WB) | WB : 1:5000-1:50000 |
| Positive WB detected in | Daudi cells |
| Western Blot (WB) | WB : 1:5000-1:50000 |
| Tested Reactivity | human |
| Cited Reactivity | human |
| Class | Recombinant |
| Type | Antibody |
| Immunogen | CatNo: Ag24407 Product name: Recombinant human GSDMA protein Source: e coli. -derived, PGEX-4T Tag: GST Domain: 1-146 aa of BC109197 Sequence: MTMFENVTRALARQLNPRGDLTPLDSLIDFKRFHPFCLVLRKRKSTLFWGARYVRTDYTLLDVLEPGSSPSDPTDTGNFGFKNMLDTRVEGDVDVPKTVKVKGTAGLSQNSTLEVQTLSVAPKALETLQERKLAADHPFLKEMQDQ Predict reactive species |
| Full Name | gasdermin A |
| Calculated Molecular Weight | 445 aa, 49 kDa |
| Observed Molecular Weight | 49 kDa |
| GenBank Accession Number | BC109197 |
| Gene Symbol | GSDMA |
| Gene ID (NCBI) | 284110 |
| RRID | AB_3670655 |
| Conjugate | Unconjugated |
| Purification Method | Protein A purification |
| UNIPROT ID | Q96QA5 |
| Storage Buffer | PBS with 0.02% sodium azide and 50% glycerol, pH 7.3. |
| Storage Conditions | Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20 o C storage. 20ul sizes contain 0.1% BSA. |
| WB protocol for GSDMA antibody 82920-1-RR | Download protocol |
| human | WB Nat Commun Staphylococcus aureus induces Gasdermin A-dependent keratinocyte pyroptosis. Authors - Doris L. LaRock View Article |
| Citations | 1 |
| Dilutions | WB : 1:5000-1:50000 |
| Isotype | IgG |
| Clonality | Recombinant |
| Clone Number | 230161D4 |
| Conjugation | Unconjugated |
Gasdermins, a family of five pore-forming proteins (GSDMA-GSDME) in humans expressed predominantly in the skin, mucosa and immune sentinel cells, are key executioners of inflammatory cell death (pyroptosis), which recruits immune cells to infection sites and promotes protective immunity. GSDMA was predicted to enable phosphatidylinositol-4,5-bisphosphate binding activity, phosphatidylinositol-4-phosphate binding activity, and phosphatidylserine binding activity. Involved in apoptotic process. Protocols Product Specific Protocols WB protocol for GSDMA antibody 82920-1-RR Download protocol Standard Protocols Click here to view our Standard Protocols
Publications
- Staphylococcus aureus induces Gasdermin A-dependent keratinocyte pyroptosis.
Journal: Nat Commun | Authors: Doris L. LaRock | Species: human | Application: WB
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