HSPB11 Polyclonal antibody 15732-1-AP proteintech
$149.00
In stock
SKU
15732-1-AP
| Catalog Number | 15732-1-AP |
| Synonyms | C1orf41, Heat shock protein beta 11, HSPB11, HSPCO34, IFT25, ITF25, Placental protein 25, PP25 |
| Host | Rabbit |
| Reactivity | human, mouse, rat |
| Form | Liquid |
| Formulation | PBS, Azide, Glycerol |
| Applications | WB, IHC, IF, ELISA |
| Applications | WB, ELISA |
| Host / Isotype | Rabbit / IgG |
| Tested Applications — Positive WB detected in | A549 cells, HeLa cells |
| Recommended Dilutions — Western Blot (WB) | WB : 1:1000-1:6000 |
| Positive WB detected in | A549 cells, HeLa cells |
| Western Blot (WB) | WB : 1:1000-1:6000 |
| Tested Reactivity | human, mouse, rat |
| Cited Reactivity | human, mouse, rat |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | CatNo: Ag8490 Product name: Recombinant human HSPB11 protein Source: e coli. -derived, PGEX-4T Tag: GST Domain: 1-144 aa of BC005245 Sequence: MRKIDLCLSSEGSEVILATSSDEKHPPENIIDGNPETFWTTTGMFPQEFIICFHKHVRIERLVIQSYFVQTLKIEKSTSKEPVDFEQWIEKDLVHTEGQLQNEEIVAHDGSATYLRFIIVSAFDHFASVHSVSAEGTVVSNLSS Predict reactive species |
| Full Name | heat shock protein family B (small), member 11 |
| Calculated Molecular Weight | 144 aa, 16 kDa |
| Observed Molecular Weight | 16-20 kDa |
| GenBank Accession Number | BC005245 |
| Gene Symbol | HSPB11 |
| Gene ID (NCBI) | 51668 |
| RRID | AB_2279933 |
| Conjugate | Unconjugated |
| Purification Method | Antigen affinity purification |
| UNIPROT ID | Q9Y547 |
| Storage Buffer | PBS with 0.02% sodium azide and 50% glycerol, pH 7.3. |
| Storage Conditions | Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20 o C storage. 20ul sizes contain 0.1% BSA. |
| WB protocol for HSPB11 antibody 15732-1-AP | Download protocol |
| human | WB Dev Cell The CEP19-RABL2 GTPase Complex Binds IFT-B to Initiate Intraflagellar Transport at the Ciliary Base. Authors - Tomoharu Kanie View Article |
| mouse | WB Curr Biol Rab34 is necessary for early stages of intracellular ciliogenesis. Authors - Michael W Stuck View Article |
| Citations | 20 |
| Dilutions | WB : 1:1000-1:6000 |
| Isotype | IgG |
| Clonality | Polyclonal |
| Clone Number | - |
| Conjugation | Unconjugated |
HSPB11 (Heat shock protein beta-11), also known as IFT25, was originally identified as a small heat shock protein. Recently it has been identified as a component of IFT complex B. It has been demonstrated that IFT25 is not required for ciliary assembly but is required for proper Hedgehog signaling, which in mammals occurs within cilia. Cilia lacking IFT25 have defects in the signal-dependent transport of multiple Hedgehog components and fail to activate the pathway upon stimulation. Protocols Product Specific Protocols WB protocol for HSPB11 antibody 15732-1-AP Download protocol Standard Protocols Click here to view our Standard Protocols
Publications
- Systematic proteomics of the VCP-UBXD adaptor network identifies a role for UBXN10 in regulating ciliogenesis.
Journal: Nat Cell Biol | Authors: Malavika Raman KD Validated | Species: human | Application: WB - IFT25 links the signal-dependent movement of Hedgehog components to intraflagellar transport.
Journal: Dev Cell | Authors: Keady Brian T BT | Species: mouse | Application: WB,IF - IFT27 Links the BBSome to IFT for Maintenance of the Ciliary Signaling Compartment.
Journal: Dev Cell | Authors: Thibaut Eguether | Species: mouse | Application: WB,IF - Rabl2 GTP hydrolysis licenses BBSome-mediated export to fine-tune ciliary signaling.
Journal: EMBO J | Authors: Shichao Duan | Species: mouse | Application: WB - Rab34 is necessary for early stages of intracellular ciliogenesis.
Journal: Curr Biol | Authors: Michael W Stuck | Species: mouse | Application: WB - The CEP19-RABL2 GTPase Complex Binds IFT-B to Initiate Intraflagellar Transport at the Ciliary Base.
Journal: Dev Cell | Authors: Tomoharu Kanie | Species: human | Application: WB
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