| Catalog Number | Biotin-FcA98097 |
| Synonyms | CDW50, ICAM3, CD50, ICAM 3, ICAM R |
| Host | Rabbit |
| Reactivity | human |
| Form | Liquid |
| Formulation | PBS, Azide |
| Applications | FC, ELISA |
| Host / Isotype | Rabbit / IgG |
| Tested Applications — Positive FC detected in | human PBMCs |
| Positive FC detected in | human PBMCs |
| Flow Cytometry (FC) | FC : 0.25 ug per 10^6 cells in a 100 µl suspension |
| Tested Reactivity | human |
| Class | Recombinant |
| Type | Antibody |
| Immunogen | Recombinant Protein Predict reactive species |
| Full Name | intercellular adhesion molecule 3 |
| Calculated Molecular Weight | 547 aa, 60 kDa |
| GenBank Accession Number | BC058903 |
| Gene Symbol | ICAM3/CD50 |
| Gene ID (NCBI) | 3385 |
| RRID | AB_3746914 |
| Conjugate | Biotin |
| Excitation/Emission Maxima Wavelengths | - |
| Purification Method | Protein A purification |
| UNIPROT ID | P32942 |
| Storage Buffer | PBS with 0.09% sodium azide, pH 7.3. |
| Storage Conditions | Store at 2-8°C. Avoid exposure to light. Stable for one year after shipment. |
| FC protocol for Biotin ICAM3/CD50 antibody Biotin-FcA98097 | Download protocol |
| Citations | - |
| Isotype | IgG |
| Clonality | Recombinant |
| Clone Number | 241418E8 |
| Conjugation | Biotin |
The intercellular adhesion molecule (ICAM) family is a subfamily of immunoglobulin superfamily with five known ICAM family members (ICAM1 to ICAM5) which play a role in inflammation, immune responses, and intracellular signaling (PMID: 23287428; 29477378). ICAM3, also known as CD50, is a type I transmembrane glycoprotein that contains five C2-type immunoglobulin-like domains in its extracellular region, a single transmembrane segment, and a C-terminus cytoplasmic tail. ICAM3 is selectively expressed on leukocytes (PMID: 1730916; 8132828). It is the primary ligand for LFA-1 and is involved in various immune processes, including T-cell activation, and macrophage recognition of apoptotic cells (PMID: 11812993; 23775590). Protocols Product Specific Protocols FC protocol for Biotin ICAM3/CD50 antibody Biotin-FcA98097 Download protocol Standard Protocols Click here to view our Standard Protocols
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