IL-6 Recombinant monoclonal antibody 81077-1-RR proteintech
$149.00
In stock
SKU
81077-1-RR
| Catalog Number | 81077-1-RR |
| Synonyms | IL6, B-cell stimulatory factor 2, IFN-beta-2, IL 6, Interferon beta-2 |
| Host | Rabbit |
| Reactivity | human |
| Form | Liquid |
| Formulation | PBS, Azide, Glycerol |
| Applications | WB, ELISA |
| Host / Isotype | Rabbit / IgG |
| Tested Applications — Positive WB detected in | HUVEC cells, Protein transport inhibitor treated U-87 MG cells |
| Recommended Dilutions — Western Blot (WB) | WB : 1:2000-1:10000 |
| Positive WB detected in | HUVEC cells, Protein transport inhibitor treated U-87 MG cells |
| Western Blot (WB) | WB : 1:2000-1:10000 |
| Tested Reactivity | human |
| Cited Reactivity | human |
| Class | Recombinant |
| Type | Antibody |
| Immunogen | CatNo: Ag10565 Product name: Recombinant human IL-6 protein Source: e coli. -derived, PGEX-4T Tag: GST Domain: 1-212 aa of BC015511 Sequence: MNSFSTSAFGPVAFSLGLLLVLPAAFPAPVPPGEDSKDVAAPHRQPLTSSERIDKQIRYILDGISALRKETCNKSNMCESSKEALAENNLNLPKMAEKDGCFQSGFNEETCLVKIITGLLEFEVYLEYLQNRFESSEEQARAVQMSTKVLIQFLQKKAKNLDAITTPDPTTNASLLTKLQAQNQWLQDMTTHLILRSFKEFLQSSLRALRQM Predict reactive species |
| Full Name | interleukin 6 (interferon, beta 2) |
| Calculated Molecular Weight | 212 aa, 24 kDa |
| Observed Molecular Weight | 20 kDa |
| GenBank Accession Number | BC015511 |
| Gene Symbol | IL6 |
| Gene ID (NCBI) | 3569 |
| ENSEMBL Gene ID | ENSG00000136244 |
| RRID | AB_2918927 |
| Conjugate | Unconjugated |
| Purification Method | Protein A purification |
| UNIPROT ID | P05231 |
| Storage Buffer | PBS with 0.02% sodium azide and 50% glycerol, pH 7.3. |
| Storage Conditions | Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20 o C storage. 20ul sizes contain 0.1% BSA. |
| WB protocol for IL-6 antibody 81077-1-RR | Download protocol |
| human | WB Cell Signal Oncogenic role of PLOD3 mediated by SOX9 through IL-6/JAK/STAT3 pathway in cervical cancer. Authors - Jiankui Li View Article |
| Citations | 1 |
| Dilutions | WB : 1:2000-1:10000 |
| Isotype | IgG |
| Clonality | Recombinant |
| Clone Number | 2E9 |
| Conjugation | Unconjugated |
Interleukin-6 (IL-6) is an interleukin that acts as both a pro-inflammatory and anti-inflammatory cytokine. IL-6 protein is secreted by a variety of cell types including T cells and macrophages as phosphorylated and variably glycosylated molecule. IL-6 plays an essential role in the final differentiation of B-cells into Ig-secreting cells involved in lymphocyte and monocyte differentiation. It induces myeloma and plasmacytoma growth and induces nerve cells differentiation acts on B-cells, T-cells, hepatocytes, hematopoietic progenitor cells and cells of the CNS. IL-6 is also considered a myokine, a cytokine produced from muscle, and is elevated in response to muscle contraction. IL-6 has been shown to interact with interleukin-6 receptor and glycoprotein 130. Additionally, IL-6 is involved in hematopoiesis, bone metabolism, and cancer progression, and has been defined an essential role in directing transition from innate to acquired immunity. Protocols Product Specific Protocols WB protocol for IL-6 antibody 81077-1-RR Download protocol Standard Protocols Click here to view our Standard Protocols
Publications
- Oncogenic role of PLOD3 mediated by SOX9 through IL-6/JAK/STAT3 pathway in cervical cancer.
Journal: Cell Signal | Authors: Jiankui Li | Species: human | Application: WB
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