INS Monoclonal antibody, PBS Only 66198-1-PBS proteintech
$699.00
In stock
SKU
66198-1-PBS
| Catalog Number | 66198-1-PBS |
| Synonyms | insulin, 4B6A7 |
| Host | Mouse |
| Reactivity | human, mouse, rat |
| Form | Liquid |
| Formulation | PBS Only |
| Applications | IHC, IF-P, Indirect ELISA |
| Host / Isotype | Mouse / IgG2a |
| Tested Reactivity | human, mouse, rat |
| Class | Monoclonal |
| Type | Antibody |
| Immunogen | CatNo: Ag8630 Product name: Recombinant human Insulin protein Source: e coli. -derived, PGEX-4T Tag: GST Domain: 1-110 aa of BC005255 Sequence: MALWMRLLPLLALLALWGPDPAAAFVNQHLCGSHLVEALYLVCGERGFFYTPKTRREAEDLQVGQVELGGGPGAGSLQPLALEGSLQKRGIVEQCCTSICSLYQLENYCN Predict reactive species |
| Full Name | INS |
| Calculated Molecular Weight | 110 aa, 12 kDa |
| GenBank Accession Number | BC005255 |
| Gene Symbol | INS |
| Gene ID (NCBI) | 3630 |
| RRID | AB_2881591 |
| Conjugate | Unconjugated |
| Purification Method | Protein A purification |
| UNIPROT ID | P01308 |
| Storage Buffer | PBS only, pH 7.3. |
| Storage Conditions | Store at -80°C. |
| Citations | - |
| Isotype | IgG2a |
| Clonality | Monoclonal |
| Clone Number | 4B6A7 |
| Conjugation | Unconjugated |
INS is a peptide hormone, produced by beta cells of the pancreas, and is central to regulating carbohydrate and fat metabolism in the body. It participates in glucose utilization, protein synthesis and in the formation and storage of neutral lipids. INS is synthesized as a precursor molecule, pro-INS, which is processed prior to secretion. A- and B-peptides are joined together by a disulfide bond to form INS, while the central portion of the precursor molecule is cleaved and released as the C-peptide. Defects in INS results in type 1 diabetes mellitus. INS may also exist 36 kDa form corresponding to the hexameric INS form.
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