LDHA-Specific Recombinant monoclonal antibody 84198-3-RR proteintech
$149.00
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SKU
84198-3-RR
| Catalog Number | 84198-3-RR |
| Synonyms | LDHA, 240885C7, Cell proliferation-inducing gene 19 protein, EC:1.1.1.27, lactate dehydrogenase A |
| Host | Rabbit |
| Reactivity | human, mouse, rat |
| Form | Liquid |
| Formulation | PBS, Azide, Glycerol |
| Applications | WB, FC (Intra), ELISA |
| Host / Isotype | Rabbit / IgG |
| Tested Applications — Positive WB detected in | HeLa cells, MDA-MB-231 cells, HEK-293 cells, Jurkat cells, NIH/3T3 cells, mouse skeletal muscle tissue, rat skeletal muscle tissue |
| Tested Applications — Positive FC (Intra) detected in | HepG2 cells |
| Recommended Dilutions — Western Blot (WB) | WB : 1:5000-1:50000 |
| Recommended Dilutions — Flow Cytometry (FC) (INTRA) | FC (INTRA) : 0.25 ug per 10^6 cells in a 100 µl suspension |
| Positive WB detected in | HeLa cells, MDA-MB-231 cells, HEK-293 cells, Jurkat cells, NIH/3T3 cells, mouse skeletal muscle tissue, rat skeletal muscle tissue |
| Positive FC (Intra) detected in | HepG2 cells |
| Western Blot (WB) | WB : 1:5000-1:50000 |
| Flow Cytometry (FC) (INTRA) | FC (INTRA) : 0.25 ug per 10^6 cells in a 100 µl suspension |
| Tested Reactivity | human, mouse, rat |
| Cited Reactivity | human |
| Class | Recombinant |
| Type | Antibody |
| Immunogen | Peptide Predict reactive species |
| Full Name | lactate dehydrogenase A |
| Calculated Molecular Weight | 37 kDa |
| Observed Molecular Weight | 35 kDa |
| GenBank Accession Number | NM_005566 |
| Gene Symbol | LDHA |
| Gene ID (NCBI) | 3939 |
| RRID | AB_3671753 |
| Conjugate | Unconjugated |
| Purification Method | Protein A purfication |
| UNIPROT ID | P00338 |
| Storage Buffer | PBS with 0.02% sodium azide and 50% glycerol, pH 7.3. |
| Storage Conditions | Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20 o C storage. 20ul sizes contain 0.1% BSA. |
| FC protocol for LDHA-Specific antibody 84198-3-RR | Download protocol |
| WB protocol for LDHA-Specific antibody 84198-3-RR | Download protocol |
| human | WB Cytojournal Ubiquitin C-terminal hydrolase L5 promotes the development of renal cell carcinoma through the glycolysis mediated by the phosphatidylinositol-3-kinase/protein kinase B/mammalian target of rapamycin pathway. Authors - Lin Ruan KD Validated View Article |
| Citations | 1 |
| Dilutions | WB : 1:5000-1:50000 FC (INTRA) : 0.25 ug per 10^6 cells in a 100 µl suspension |
| Isotype | IgG |
| Clonality | Recombinant |
| Clone Number | 240885C7 |
| Conjugation | Unconjugated |
LDHA, also named as LDH-M and NY-REN-59, is an enzyme which catalyzes the inter-conversion of pyruvate and L-lactate with concomitant inter-conversion of NADH and NAD+. LDHA is found in most somatic tissues, though predominantly in muscle tissue and tumours, and belongs to the lactate dehydrogenase family. It has long been known that many human cancers have higher LDHA levels compared to normal tissues. It has also been shown that LDHA plays an important role in the development, invasion and metastasis of malignancies. Protocols Product Specific Protocols FC protocol for LDHA-Specific antibody 84198-3-RR Download protocol WB protocol for LDHA-Specific antibody 84198-3-RR Download protocol Standard Protocols Click here to view our Standard Protocols
Publications
- Ubiquitin C-terminal hydrolase L5 promotes the development of renal cell carcinoma through the glycolysis mediated by the phosphatidylinositol-3-kinase/protein kinase B/mammalian target of rapamycin pathway.
Journal: Cytojournal | Authors: Lin Ruan KD Validated | Species: human | Application: WB
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