CoraLite®594-conjugated INS Monoclonal antibody CL594-66198 proteintech
$479.00
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SKU
CL594-66198
| Catalog Number | CL594-66198 |
| Synonyms | ILPR, INS, IRDN |
| Host | Mouse |
| Reactivity | human, mouse, rat |
| Form | Liquid |
| Formulation | PBS, Proclin300, BSA, Glycerol |
| Applications | IF-P |
| Host / Isotype | Mouse / IgG2a |
| Tested Applications — Positive IF-P detected in | mouse pancreas tissue |
| Recommended Dilutions — Immunofluorescence (IF)-P | IF-P : 1:200-1:800 |
| Positive IF-P detected in | mouse pancreas tissue |
| Immunofluorescence (IF)-P | IF-P : 1:200-1:800 |
| Tested Reactivity | human, mouse, rat |
| Class | Monoclonal |
| Type | Antibody |
| Immunogen | CatNo: Ag8630 Product name: Recombinant human Insulin protein Source: e coli. -derived, PGEX-4T Tag: GST Domain: 1-110 aa of BC005255 Sequence: MALWMRLLPLLALLALWGPDPAAAFVNQHLCGSHLVEALYLVCGERGFFYTPKTRREAEDLQVGQVELGGGPGAGSLQPLALEGSLQKRGIVEQCCTSICSLYQLENYCN Predict reactive species |
| Full Name | INS |
| Calculated Molecular Weight | 110 aa, 12 kDa |
| GenBank Accession Number | BC005255 |
| Gene Symbol | INS |
| Gene ID (NCBI) | 3630 |
| RRID | AB_2883532 |
| Conjugate | CoraLite®594 Fluorescent Dye |
| Excitation/Emission Maxima Wavelengths | 588 nm / 604 nm |
| Excitation Laser | Yellow-Green Laser (561 nm) |
| Purification Method | Protein A purification |
| UNIPROT ID | P01308 |
| Storage Buffer | PBS with 50% glycerol, 0.05% Proclin300, 0.5% BSA, pH 7.3. |
| Storage Conditions | Store at -20°C. Avoid exposure to light. Stable for one year after shipment. Aliquoting is unnecessary for -20 o C storage. |
| IF protocol for CL594 INS antibody CL594-66198 | Download protocol |
| Citations | 1 |
| Dilutions | IF-P : 1:200-1:800 |
| Isotype | IgG2a |
| Clonality | Monoclonal |
| Clone Number | 4B6A7 |
| Conjugation | CoraLite®594 |
INS is a peptide hormone, produced by beta cells of the pancreas, and is central to regulating carbohydrate and fat metabolism in the body. It participates in glucose utilization, protein synthesis and in the formation and storage of neutral lipids. It is synthesized as a precursor molecule, which is processed prior to secretion. A- and B-peptides are joined together by a disulfide bond to form INS, while the central portion of the precursor molecule is cleaved and released as the C-peptide. Defects in INS results in type 1 diabetes mellitus. INS may also exist 36 kDa form corresponding to the hexameric INS form. Protocols Product Specific Protocols IF protocol for CL594 INS antibody CL594-66198 Download protocol Standard Protocols Click here to view our Standard Protocols
Publications
- Densely vascularized thick 3D tissue shows enhanced protein secretion constructed with intermittent positive pressure
Journal: Commun Biol | Authors: Misako Katsuura
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