JAM2 Polyclonal antibody 12972-1-AP proteintech
$149.00
In stock
SKU
12972-1-AP
| Catalog Number | 12972-1-AP |
| Synonyms | C21orf43, CD322, JAM-2, JAMB, JAM-B |
| Host | Rabbit |
| Reactivity | human, mouse, rat |
| Form | Liquid |
| Formulation | PBS, Azide, Glycerol |
| Applications | WB, ELISA |
| Host / Isotype | Rabbit / IgG |
| Tested Applications — Positive WB detected in | human placenta tissue, human heart tissue |
| Recommended Dilutions — Western Blot (WB) | WB : 1:500-1:2000 |
| Positive WB detected in | human placenta tissue, human heart tissue |
| Western Blot (WB) | WB : 1:500-1:2000 |
| Tested Reactivity | human, mouse, rat |
| Cited Reactivity | human, mouse, rat |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | CatNo: Ag3431 Product name: Recombinant human JAM2 protein Source: e coli. -derived, PGEX-4T Tag: GST Domain: 1-298 aa of BC017779 Sequence: MARRSRHRLLLLLLRYLVVALGYHKAYGFSAPKDQQVVTAVEYQEAILACKTPKKTVSSRLEWKKLGRSVSFVYYQQTLQGDFKNRAEMIDFNIRIKNVTRSDAGKYRCEVSAPSEQGQNLEEDTVTLEVLVAPAVPSCEVPSSALSGTVVELRCQDKEGNPAPEYTWFKDGIRLLENPRLGSQSTNSSYTMNTKTGTLQFNTVSKLDTGEYSCEARNSVGYRRCPGKRMQVDDLNISGIIAAVVVVALVISVCGLGVCYAQRKGYFSKETSFQKSNSSSKATTMSENDFKHTKSFII Predict reactive species |
| Full Name | junctional adhesion molecule 2 |
| Calculated Molecular Weight | 298 aa, 33 kDa |
| Observed Molecular Weight | 33 kDa, 43 kDa |
| GenBank Accession Number | BC017779 |
| Gene Symbol | JAM2 |
| Gene ID (NCBI) | 58494 |
| RRID | AB_10638910 |
| Conjugate | Unconjugated |
| Purification Method | Antigen affinity purification |
| UNIPROT ID | P57087 |
| Storage Buffer | PBS with 0.02% sodium azide and 50% glycerol, pH 7.3. |
| Storage Conditions | Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20 o C storage. 20ul sizes contain 0.1% BSA. |
| WB protocol for JAM2 antibody 12972-1-AP | Download protocol |
| human | WB Cell Death Discov HSP90AA1 restrains clear cell renal cell carcinoma progression by promoting CADM1 expression and suppressing the PI3K-AKT pathway through interaction with FBXO7. Authors - Wuping Yang View Article |
| mouse | WB Diabetes Res Clin Pract Heparanase-driven inflammation from the AGEs-stimulated macrophages changes the functions of glomerular endothelial cells. Authors - Guang Xu View Article |
| rat | WB Mol Cell Endocrinol PPM1G dephosphorylates α-catenin to maintain the integrity of adherens junctions and regulates apoptosis in Sertoli cells Authors - Xinyao Li View Article |
| Citations | 4 |
| Dilutions | WB : 1:500-1:2000 |
| Isotype | IgG |
| Clonality | Polyclonal |
| Clone Number | - |
| Conjugation | Unconjugated |
Junctional adhesion molecules (JAMs) are integral membrane proteins belonging to the immunoglobulin (Ig) superfamily. JAMs are expressed by leukocytes, platelets, endothelial, and epithelial cells and localized at the tight junction of polarized cells and on the cell surface of leukocytes. JAM-2, also known as VE-JAM or JAM-B, is specifically expressed in lymphatic endothelial cells and endothelial venules. JAM2 regulates cell-cell adhesion and signaling by interacting with other tight junction proteins such as PAR-3 and ZO-1.(PMID: 14657270; PMID: 24595739; PMID: 11739175; PMID: 12953056) Protocols Product Specific Protocols WB protocol for JAM2 antibody 12972-1-AP Download protocol Standard Protocols Click here to view our Standard Protocols
Publications
- Porphyromonas gingivalis induces penetration of lipopolysaccharide and peptidoglycan through the gingival epithelium via degradation of coxsackievirus and adenovirus receptor.
Journal: Cell Microbiol | Authors: Hiroki Takeuchi | Species: human | Application: WB - Heparanase-driven inflammation from the AGEs-stimulated macrophages changes the functions of glomerular endothelial cells.
Journal: Diabetes Res Clin Pract | Authors: Guang Xu | Species: mouse | Application: WB - PPM1G dephosphorylates α-catenin to maintain the integrity of adherens junctions and regulates apoptosis in Sertoli cells
Journal: Mol Cell Endocrinol | Authors: Xinyao Li | Species: rat | Application: WB - HSP90AA1 restrains clear cell renal cell carcinoma progression by promoting CADM1 expression and suppressing the PI3K-AKT pathway through interaction with FBXO7.
Journal: Cell Death Discov | Authors: Wuping Yang | Species: human | Application: WB
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