Shootin 1 Polyclonal antibody 24383-1-AP proteintech
$149.00
In stock
SKU
24383-1-AP
| Catalog Number | 24383-1-AP |
| Synonyms | SHTN1, KIAA1598, Shootin-1 |
| Host | Rabbit |
| Reactivity | human, mouse, rat |
| Form | Liquid |
| Formulation | PBS, Azide, Glycerol |
| Applications | WB, IHC, ELISA |
| Host / Isotype | Rabbit / IgG |
| Tested Applications — Positive WB detected in | SH-SY5Y cells, Neuro-2a cells, SK-N-SH cells |
| Tested Applications — Positive IHC detected in | human bowen disease Note: suggested antigen retrieval with TE buffer pH 9.0; (*) Alternatively, antigen retrieval may be performed with citrate buffer pH 6.0 |
| Recommended Dilutions — Western Blot (WB) | WB : 1:500-1:3000 |
| Recommended Dilutions — Immunohistochemistry (IHC) | IHC : 1:50-1:500 |
| Positive WB detected in | SH-SY5Y cells, Neuro-2a cells, SK-N-SH cells |
| Positive IHC detected in | human bowen disease Note: suggested antigen retrieval with TE buffer pH 9.0; (*) Alternatively, antigen retrieval may be performed with citrate buffer pH 6.0 |
| Western Blot (WB) | WB : 1:500-1:3000 |
| Immunohistochemistry (IHC) | IHC : 1:50-1:500 |
| Tested Reactivity | human, mouse, rat |
| Cited Reactivity | human |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | CatNo: Ag18294 Product name: Recombinant human KIAA1598 protein Source: e coli. -derived, PGEX-4T Tag: GST Domain: 834-1066 aa of BC022348 Sequence: TEEVTDLKRQAVEEMMDRIKKGVHLRPVNQTARPKTKPESSKGCESAVDELKGILGTLNKSTSSRSLKSLDPENSETELERILRRRKVTAEADSSSPTGILATSESKSMPVLGSVSSVTKTALNKKTLEAEFNSPSPPTPEPGEGPRKLEGCTSSKVTFQPPSSIGCRKKYIDGEKQAEPVVVLDPVSTHEPQTKDQVAEKDPTQHKEDEGEIQPENKEDSIENVRETDSSNC Predict reactive species |
| Full Name | KIAA1598 |
| Calculated Molecular Weight | 72 kDa |
| Observed Molecular Weight | 60-80 kDa |
| GenBank Accession Number | BC022348 |
| Gene Symbol | Shootin 1 |
| Gene ID (NCBI) | 57698 |
| RRID | AB_2879517 |
| Conjugate | Unconjugated |
| Purification Method | Antigen affinity purification |
| UNIPROT ID | A0MZ66 |
| Storage Buffer | PBS with 0.02% sodium azide and 50% glycerol, pH 7.3. |
| Storage Conditions | Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20 o C storage. 20ul sizes contain 0.1% BSA. |
| IHC protocol for Shootin 1 antibody 24383-1-AP | Download protocol |
| WB protocol for Shootin 1 antibody 24383-1-AP | Download protocol |
| human | WB,IHC Cancer Genet Data-mining-based biomarker evaluation and experimental validation of SHTN1 for bladder cancer Authors - Yueying Wang View Article |
| Citations | 1 |
| Dilutions | WB : 1:500-1:3000 IHC : 1:50-1:500 |
| Isotype | IgG |
| Clonality | Polyclonal |
| Clone Number | - |
| Conjugation | Unconjugated |
Shootin 1, also known as SHTN1, KIAA1598, contains 3 coiled-coil domains and a proline-rich region. Shootin 1 is involved in generating internal asymmetric signals required for neuronal during stages 2 and 3. Shootin 1 plays a role in cytoskeletal organization by regulating the subcellular localization of phosphoinositide 3-kinase (PI3K) activity at the axonal growth cone. SHTN1 produces 2 splice variants, a short variant, SHTN1S, that lacks exons 15 and 16, and a long variant, SHTN1L, that includes exons 1 through 17(PMID: 17030985, 30733148). Protocols Product Specific Protocols IHC protocol for Shootin 1 antibody 24383-1-AP Download protocol WB protocol for Shootin 1 antibody 24383-1-AP Download protocol Standard Protocols Click here to view our Standard Protocols
Publications
- Data-mining-based biomarker evaluation and experimental validation of SHTN1 for bladder cancer
Journal: Cancer Genet | Authors: Yueying Wang | Species: human | Application: WB,IHC
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