LETM1 Monoclonal antibody, PBS Only (Detector) 68208-1-PBS proteintech
$699.00
In stock
SKU
68208-1-PBS
| Catalog Number | 68208-1-PBS |
| Synonyms | 2B9B9, Leucine zipper-EF-hand-containing transmembrane protein 1 |
| Host | Mouse |
| Reactivity | human, rat |
| Form | Liquid |
| Formulation | PBS Only |
| Applications | WB, IHC, IF/ICC, Cytometric bead array, Indirect ELISA |
| Host / Isotype | Mouse / IgG1 |
| Tested Reactivity | human, rat |
| Class | Monoclonal |
| Type | Antibody |
| Immunogen | CatNo: Ag8851 Product name: Recombinant human LETM1 protein Source: e coli. -derived, PET28a Tag: 6*His Domain: 391-739 aa of BC021208 Sequence: EDRLRGQLKQWLDLHLHQEIPTSLLILSRAMYLPDTLSPADQLKSTLQTLPEIVAKEAQVKVAEVEGEQVDNKAKLEATLQEEAAIQQEHREKELQKRSEVAKDFEPERVVAAPQRPGTEPQPEMPDTVLQSETLKDTAPVLEGLKEEEITKEEIDILSDACSKLQEQKKSLTKEKEELELLKEDVQDYSEDLQEIKKELSKTGEEKYVEESKASKRLTKRVQQMIGQIDGLISQLEMDQQAGKLAPANGMPTGENVISVAELINAMKQVKHIPESKLTSLAAALDENKDGKVNIDDLVKVIELVDKEDVHISTSQVAEIVATLEKEEKVEEKEKAKEKAEKEVAEVKS Predict reactive species |
| Full Name | leucine zipper-EF-hand containing transmembrane protein 1 |
| Calculated Molecular Weight | 739 aa, 83 kDa |
| Observed Molecular Weight | 83 kDa |
| GenBank Accession Number | BC021208 |
| Gene Symbol | LETM1 |
| Gene ID (NCBI) | 3954 |
| RRID | AB_2935296 |
| Conjugate | Unconjugated |
| Purification Method | Protein G purification |
| UNIPROT ID | O95202 |
| Storage Buffer | PBS only, pH 7.3. |
| Storage Conditions | Store at -80°C. |
| Citations | - |
| Isotype | IgG1 |
| Clonality | Monoclonal |
| Clone Number | 2B9B9 |
| Conjugation | Unconjugated |
LETM1 is a mitochondrial inner membrane protein. It functions to maintain the mitochondrial tubular shapes and is required for normal mitochondrial morphology and cellular viability. It served as an anchor protein for complex formation between mitochondria and ribosome, and regulated mitochondrial biogenesis. It was also identified inWolf-Hirschhorn syndrome, and was deleted in nearly all patients with the syndrome. A recent study determined that adenovirus-mediated LETM1 may provide a useful target for designing lung tumor prevention and treatment.
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