TREM2 Recombinant monoclonal antibody 83438-6-RR proteintech
$149.00
In stock
SKU
83438-6-RR
| Catalog Number | 83438-6-RR |
| Synonyms | 240384B7, TREM 2, TREM-2, Trem2a, Trem2b |
| Host | Rabbit |
| Reactivity | human and More (1) |
| Reactivity | human, mouse |
| Form | Liquid |
| Formulation | PBS, Azide, Glycerol |
| Applications | WB, IHC, IF, ELISA |
| Applications | WB, ELISA |
| Host / Isotype | Rabbit / IgG |
| Tested Applications — Positive WB detected in | PMA treated THP-1 cells, THP-1 cells |
| Recommended Dilutions — Western Blot (WB) | WB : 1:2000-1:10000 |
| Positive WB detected in | PMA treated THP-1 cells, THP-1 cells |
| Western Blot (WB) | WB : 1:2000-1:10000 |
| Tested Reactivity | human |
| Cited Reactivity | human, mouse |
| Class | Recombinant |
| Type | Antibody |
| Immunogen | CatNo: Eg0747 Product name: Recombinant human TREM2 protein Source: mammalian cells -derived, pHZ-KIsec-C-6*HIS Tag: C-6*HIS Domain: 19-174 aa of BC032362 Sequence: HNTTVFQGVAGQSLQVSCPYDSMKHWGRRKAWCRQLGEKGPCQRVVSTHNLWLLSFLRRWNGSTAITDDTLGGTLTITLRNLQPHDAGLYQCQSLHGSEADTLRKVLVEVLADPLDHRDAGDLWFPGESESFEDAHVEHSISRPSQGSHLPSCLSK Predict reactive species |
| Full Name | triggering receptor expressed on myeloid cells 2 |
| Calculated Molecular Weight | 222 aa, 25 kDa |
| Observed Molecular Weight | 26-32 kDa |
| GenBank Accession Number | BC032362 |
| Gene Symbol | TREM2 |
| Gene ID (NCBI) | 54209 |
| RRID | AB_3671079 |
| Conjugate | Unconjugated |
| Purification Method | Protein A purfication |
| UNIPROT ID | Q9NZC2 |
| Storage Buffer | PBS with 0.02% sodium azide and 50% glycerol, pH 7.3. |
| Storage Conditions | Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20 o C storage. 20ul sizes contain 0.1% BSA. |
| WB protocol for TREM2 antibody 83438-6-RR | Download protocol |
| mouse | WB ACS Infect Dis A Photoactivatable Free Mycolic Acid Probe to Investigate Mycobacteria-Host Interactions Authors - Kingsley C Agu View Article |
| human | WB Adv Sci (Weinh) Cancer Cell-Intrinsic Cholesterol Induces Lipid-Associated Macrophage Differentiation via SP1 Palmitoylation to Promote Prostate Cancer Progression Authors - Shirong Peng View Article |
| Christin (Verified Customer) (12-22-2025) | Great antibody for western blot! Applications: Western Blot Primary Antibody Dilution: 1:5000 Cell Tissue Type: Microglia |
| Alicia (Verified Customer) (10-07-2025) | Cortical organoid Applications: Immunofluorescence Primary Antibody Dilution: 1:1000 Cell Tissue Type: Cortical organoid from iPSC control |
| Citations | 5 |
| Dilutions | WB : 1:2000-1:10000 |
| Isotype | IgG |
| Clonality | Recombinant |
| Clone Number | 240384B7 |
| Conjugation | Unconjugated |
TREM2 (triggering receptor expressed on myeloid cells 2) is a cell surface receptor belongs to TREM family that is expressed on osteoclast, dendritic cells, macrophages, nature killers, neutrophils and microglia (PMID: 19302484). TREM2 is localized predominantly in the Golgi complex, but also shuttles to and from the cell surface in endocytic and exocytic vesicles (PMID: 16675145). TREM2 associates with DAP12 to initiate the intracellular signalling cascade via an immunoreceptor tyrosine-based activation motif (ITAM) domain and tyrosine-kinases (PMID: 23977213). Protocols Product Specific Protocols WB protocol for TREM2 antibody 83438-6-RR Download protocol Standard Protocols Click here to view our Standard Protocols
Publications
- TREM2 alleviates sepsis-induced acute lung injury by attenuating ferroptosis via the SHP1/STAT3 pathway
Journal: Free Radic Biol Med | Authors: Siyi Wu | Species: mouse | Application: WB - Circadian rhythm disruption aggravates periodontitis via orchestrating TREM2+ macrophage-mediated bone resorption.
Journal: Life Sci | Authors: Pei Wu KD Validated | Species: mouse | Application: WB,IHC,IF - Cancer Cell-Intrinsic Cholesterol Induces Lipid-Associated Macrophage Differentiation via SP1 Palmitoylation to Promote Prostate Cancer Progression
Journal: Adv Sci (Weinh) | Authors: Shirong Peng | Species: human | Application: WB - Modulating Amyloid Pathology-Neural Hyperexcitability Crosstalk for Alzheimer's Disease Therapy.
Journal: ACS Nano | Authors: Ying Wang | Species: mouse | Application: WB - A Photoactivatable Free Mycolic Acid Probe to Investigate Mycobacteria-Host Interactions
Journal: ACS Infect Dis | Authors: Kingsley C Agu | Species: mouse | Application: WB
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