| Catalog Number | 65622-1-MR |
| Synonyms | C3b/C4b receptor, C3BR, Complement receptor type 1, CR1, E11 |
| Host | Mouse |
| Reactivity | human and More (1) |
| Reactivity | human, rat |
| Form | Liquid |
| Formulation | PBS, Azide |
| Applications | FC |
| Host / Isotype | Mouse / IgG2a |
| Tested Applications — Positive FC detected in | human PBMCs |
| Positive FC detected in | human PBMCs |
| Flow Cytometry (FC) | FC : 0.25 ug per 10^6 cells in 100 μl suspension |
| Tested Reactivity | human |
| Cited Reactivity | rat |
| Class | Recombinant |
| Type | Antibody |
| Immunogen | Human CD35 from Acute monocytic leukemia cells and normal blood monocytes Predict reactive species |
| Full Name | complement component (3b/4b) receptor 1 (Knops blood group) |
| Calculated Molecular Weight | 224 kDa |
| GenBank Accession Number | NM_000573 |
| Gene Symbol | CR1 |
| Gene ID (NCBI) | 1378 |
| ENSEMBL Gene ID | ENSG00000203710 |
| RRID | AB_3670365 |
| Conjugate | Unconjugated |
| Purification Method | Protein A purification |
| UNIPROT ID | P17927 |
| Storage Buffer | PBS with 0.09% sodium azide, pH 7.3. |
| Storage Conditions | Store at 2-8°C. Stable for one year after shipment. |
| FC protocol for CD35 antibody 65622-1-MR | Download protocol |
| rat | FC Mater Today Bio Exosome-loaded tannic acid-thioctic acid hydrogel enhances wound healing in coagulation disorders Authors - Yuesheng Tu View Article |
| Citations | 1 |
| Isotype | IgG2a |
| Clonality | Recombinant |
| Clone Number | E11 |
| Conjugation | Unconjugated |
CD35, also known as complement receptor type 1 (CR1) or C3b/C4b receptor, is a single-chain glycoprotein consisting of 30 repeating homologous protein domains known as short consensus repeats (~60 amino acids each) followed by transmembrane and cytoplasmic domains (PMID: 8765013). CD35 is variably expressed by granulocytes, monocytes, B cells, some T cells, erythrocytes, follicular dendritic cells, Langerhans cells, and glomerular podocytes (PMID: 19004497). CD35 acts as a receptor for C3b and C4b and plays important roles in the regulation of the complement cascade and clearance of immune complexes. Protocols Product Specific Protocols FC protocol for CD35 antibody 65622-1-MR Download protocol Standard Protocols Click here to view our Standard Protocols
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