EDG7-Specific Polyclonal antibody 19509-1-AP proteintech
$149.00
In stock
SKU
19509-1-AP
| Catalog Number | 19509-1-AP |
| Synonyms | LPAR3, Edg 7, EDG7, GPCR, HOFNH30 |
| Host | Rabbit |
| Reactivity | human, mouse, rat |
| Form | Liquid |
| Formulation | PBS, Azide, Glycerol |
| Applications | WB, IHC, IF, ELISA |
| Applications | WB, IHC, ELISA |
| Host / Isotype | Rabbit / IgG |
| Tested Applications — Positive WB detected in | HepG2 cells, human testis tissue, mouse pancreas tissue, PC-3 cells, L02 cells, MKN-45 cells |
| Tested Applications — Positive IHC detected in | mouse heart tissue, human heart tissue Note: suggested antigen retrieval with TE buffer pH 9.0; (*) Alternatively, antigen retrieval may be performed with citrate buffer pH 6.0 |
| Recommended Dilutions — Western Blot (WB) | WB : 1:500-1:2000 |
| Recommended Dilutions — Immunohistochemistry (IHC) | IHC : 1:200-1:800 |
| Positive WB detected in | HepG2 cells, human testis tissue, mouse pancreas tissue, PC-3 cells, L02 cells, MKN-45 cells |
| Positive IHC detected in | mouse heart tissue, human heart tissue Note: suggested antigen retrieval with TE buffer pH 9.0; (*) Alternatively, antigen retrieval may be performed with citrate buffer pH 6.0 |
| Western Blot (WB) | WB : 1:500-1:2000 |
| Immunohistochemistry (IHC) | IHC : 1:200-1:800 |
| Tested Reactivity | human, mouse, rat |
| Cited Reactivity | human, mouse |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Peptide Predict reactive species |
| Full Name | lysophosphatidic acid receptor 3 |
| Calculated Molecular Weight | 40 kDa |
| Observed Molecular Weight | 40-50 kDa |
| GenBank Accession Number | NM_012152 |
| Gene Symbol | LPAR3 |
| Gene ID (NCBI) | 23566 |
| RRID | AB_10641042 |
| Conjugate | Unconjugated |
| Purification Method | Antigen affinity purification |
| UNIPROT ID | Q9UBY5 |
| Storage Buffer | PBS with 0.02% sodium azide and 50% glycerol, pH 7.3. |
| Storage Conditions | Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20 o C storage. 20ul sizes contain 0.1% BSA. |
| IHC protocol for EDG7-Specific antibody 19509-1-AP | Download protocol |
| WB protocol for EDG7-Specific antibody 19509-1-AP | Download protocol |
| human | IHC Comput Struct Biotechnol J Interrelations of Sphingolipid and Lysophosphatidate Signaling with Immune System in Ovarian Cancer. Authors - Anastasia Meshcheryakova View Article |
| mouse | WB Pediatr Res Bronchopulmonary dysplasia demonstrates dysregulated autotaxin/lysophosphatidic acid signaling in a neonatal mouse model Authors - Alison W Ha View Article |
| Citations | 5 |
| Dilutions | WB : 1:500-1:2000 IHC : 1:200-1:800 |
| Isotype | IgG |
| Clonality | Polyclonal |
| Clone Number | - |
| Conjugation | Unconjugated |
LPAR3, also named EDG7 and LPA3, belongs to the G-protein coupled receptor 1 family. LPAR3 is a receptor for lysophosphatidic acid (LPA), a mediator of diverse cellular activities. LPAR3 may play a role in the development of ovarian cancer. Seems to be coupled to the G(i)/G(o) and G(q) families of heteromeric G proteins. The antibody is specific to LPAR3. Protocols Product Specific Protocols IHC protocol for EDG7-Specific antibody 19509-1-AP Download protocol WB protocol for EDG7-Specific antibody 19509-1-AP Download protocol Standard Protocols Click here to view our Standard Protocols
Publications
- Time-series single-cell transcriptomic profiling of luteal-phase endometrium uncovers dynamic characteristics and its dysregulation in recurrent implantation failures
Journal: Nat Commun | Authors: Dandan Cao | Species: human | Application: IF - Interrelations of Sphingolipid and Lysophosphatidate Signaling with Immune System in Ovarian Cancer.
Journal: Comput Struct Biotechnol J | Authors: Anastasia Meshcheryakova | Species: human | Application: IHC - Lpar3-mediated macrophage polarization promotes inflammatory tooth extraction socket healing and alveolar bone regeneration.
Journal: Regen Ther | Authors: Na Zhang | Species: mouse | Application: IF - Bronchopulmonary dysplasia demonstrates dysregulated autotaxin/lysophosphatidic acid signaling in a neonatal mouse model
Journal: Pediatr Res | Authors: Alison W Ha | Species: mouse | Application: WB - LACC1 attenuates LPS-induced acute lung injury by inhibiting inflammatory response in alveolar macrophage through LPAR3/PI3K/AKT/mTOR signaling pathway.
Journal: Biomark Res | Authors: Yiran He
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