CoraLite® Plus 488 Anti-Human LRP1 (5A6) Mouse IgG2a Recombinant Antibody CL488-65594 proteintech
$170.00
In stock
SKU
CL488-65594
| Catalog Number | CL488-65594 |
| Synonyms | 5A6, A2MR, Alpha 2 macroglobulin receptor, Alpha-2-macroglobulin receptor, APOER |
| Host | Mouse |
| Reactivity | human |
| Form | Liquid |
| Formulation | PBS, Azide, BSA |
| Applications | FC |
| Host / Isotype | Mouse / IgG2a |
| Tested Applications — Positive FC detected in | U-87 MG cells |
| Positive FC detected in | U-87 MG cells |
| Flow Cytometry (FC) | FC : 5 ul per 10^6 cells in a 100 µl suspension |
| Tested Reactivity | human |
| Class | Recombinant |
| Type | Antibody |
| Immunogen | Full length native protein (purified) Predict reactive species |
| Full Name | low density lipoprotein-related protein 1 (alpha-2-macroglobulin receptor) |
| Calculated Molecular Weight | 505 kDa |
| GenBank Accession Number | BC045107 |
| Gene Symbol | LRP1 |
| Gene ID (NCBI) | 4035 |
| RRID | AB_3747246 |
| Conjugate | CoraLite® Plus 488 Fluorescent Dye |
| Excitation/Emission Maxima Wavelengths | 493 nm / 522 nm |
| Excitation Laser | Blue laser (488 nm) |
| Purification Method | Protein A purification |
| UNIPROT ID | Q07954 |
| Storage Buffer | PBS with 0.09% sodium azide and 0.5% BSA, pH 7.3. |
| Storage Conditions | Store at 2-8°C. Avoid exposure to light. Stable for one year after shipment. |
| FC protocol for CL Plus 488 LRP1 antibody CL488-65594 | Download protocol |
| Citations | - |
| Isotype | IgG2a |
| Clonality | Recombinant |
| Clone Number | 5A6 |
| Conjugation | CoraLite® Plus 488 |
LRP1 (Prolow-density lipoprotein receptor-related protein 1), also known as A2MR, APOER and CD91, is a type I transmembrane protein that belongs to the LDLR family. LRP1 is synthesized as a transmembrane glycosylated precursor of 600 kDa, and is subsequently cleaved to generate a large 515-kDa N-terminal extracellular subunit and an 85-kDa C-terminal transmembrane subunit, which are noncovalently associated with one another (PMID: 2112085; 8546712). LRP1 is a multifunctional receptor involved in the clearance of a large number of diverse ligands and modulating various cellular processes. LRP1 is implicated in conditions such as atherosclerosis, cancer and neurodegenerative diseases (PMID: 28381441). Protocols Product Specific Protocols FC protocol for CL Plus 488 LRP1 antibody CL488-65594 Download protocol Standard Protocols Click here to view our Standard Protocols
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