LRRC8C Monoclonal antibody, PBS Only 68323-1-PBS proteintech
$699.00
In stock
SKU
68323-1-PBS
| Catalog Number | 68323-1-PBS |
| Synonyms | AD158, DKFZp586J1119, FAD158, LRRC8C |
| Host | Mouse |
| Reactivity | Human |
| Reactivity | human |
| Form | Liquid |
| Formulation | PBS Only |
| Applications | WB, IF/ICC, Indirect ELISA |
| Host / Isotype | Mouse / IgG2b |
| Tested Reactivity | Human |
| Class | Monoclonal |
| Type | Antibody |
| Immunogen | CatNo: Ag17001 Product name: Recombinant human LRRC8C protein Source: e coli. -derived, PET28a Tag: 6*His Domain: 618-803 aa of BC113973 Sequence: DLKENNLKSIEEIVSFQHLRKLTVLKLWHNSITYIPEHIKKLTSLERLSFSHNKIEVLPSHLFLCNKIRYLDLSYNDIRFIPPEIGVLQSLQYFSITCNKVESLPDELYFCKKLKTLKIGKNSLSVLSPKIGNLLFLSYLDVKGNHFEILPPELGDCRALKRAGLVVEDALFETLPSDVREQMKTE Predict reactive species |
| Full Name | leucine rich repeat containing 8 family, member C |
| Calculated Molecular Weight | 803 aa, 92 kDa |
| Observed Molecular Weight | 105 kDa |
| GenBank Accession Number | BC113973 |
| Gene Symbol | LRRC8C |
| Gene ID (NCBI) | 84230 |
| RRID | AB_2935395 |
| Conjugate | Unconjugated |
| Purification Method | Protein A purification |
| UNIPROT ID | Q8TDW0 |
| Storage Buffer | PBS only, pH 7.3. |
| Storage Conditions | Store at -80°C. |
| Citations | - |
| Isotype | IgG2b |
| Clonality | Monoclonal |
| Clone Number | 4A6A4 |
| Conjugation | Unconjugated |
LRRC8C (Leucine-rich repeat-containing protein 8C), also known as AD158, is a non-essential component of the volume-regulated anion channel (VRAC, also known as VSOAC channel), which is required to maintain a constant cell volume in response to extracellular or intracellular permeability changes. The VRAC channel conducts iodide better than chloride and can also conduct organic osmolytes like taurine. The VRAC channel also mediates transport of immunoreactive cyclic dinucleotide GMP-AMP (2'-3'-cGAMP), an immune messenger produced in response to DNA virus in the cytosol (PMID:24790029; 26824658; 28193731).
Reviews
Write Your Own Review
Related Products
Check items to add to the cart or
