ACVRL1 Recombinant monoclonal antibody 84421-3-RR proteintech
$149.00
In stock
SKU
84421-3-RR
| Catalog Number | 84421-3-RR |
| Synonyms | ALK1, ALK 1, ACVRLK1, Activin receptor-like kinase 1, Activin receptor like kinase 1 |
| Host | Rabbit |
| Reactivity | human |
| Form | Liquid |
| Formulation | PBS, Azide, Glycerol |
| Applications | WB, ELISA |
| Host / Isotype | Rabbit / IgG |
| Tested Applications — Positive WB detected in | HUVEC cells |
| Recommended Dilutions — Western Blot (WB) | WB : 1:1000-1:4000 |
| Positive WB detected in | HUVEC cells |
| Western Blot (WB) | WB : 1:1000-1:4000 |
| Tested Reactivity | human |
| Class | Recombinant |
| Type | Antibody |
| Immunogen | FusionProtein Predict reactive species |
| Full Name | activin A receptor type II-like 1 |
| Calculated Molecular Weight | 56 kDa |
| Observed Molecular Weight | 63 kDa |
| GenBank Accession Number | BC042637 |
| Gene Symbol | ACVRL1 |
| Gene ID (NCBI) | 94 |
| RRID | AB_3671949 |
| Conjugate | Unconjugated |
| Purification Method | Protein A purfication |
| UNIPROT ID | P37023 |
| Storage Buffer | PBS with 0.02% sodium azide and 50% glycerol, pH 7.3. |
| Storage Conditions | Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20 o C storage. 20ul sizes contain 0.1% BSA. |
| WB protocol for ACVRL1 antibody 84421-3-RR | Download protocol |
| Citations | - |
| Dilutions | WB : 1:1000-1:4000 |
| Isotype | IgG |
| Clonality | Recombinant |
| Clone Number | 241686H2 |
| Conjugation | Unconjugated |
ACVRL1 (ALK1) is a type I cell-surface receptor for the TGF-beta superfamily of ligands. It shares with other type I receptors a high degree of similarity in serine-threonine kinase subdomains, a glycine- and serine-rich region (called the GS domain) preceding the kinase domain, and a short C-terminal tail. ACVRL1 is highly expressed in endothelial cells and has a critical role in the control of blood vessel development and repair (PMID: 8640225). Mutations in the ACVRL1 gene are associated with hemorrhagic telangiectasia type 2. Protocols Product Specific Protocols WB protocol for ACVRL1 antibody 84421-3-RR Download protocol Standard Protocols Click here to view our Standard Protocols
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