Anti-Human ALCAM (3A6) Mouse IgG2a Recombinant Antibody 65611-1-MR proteintech
$80.00
In stock
SKU
65611-1-MR
| Catalog Number | 65611-1-MR |
| Synonyms | 3A6, CD166, MEMD |
| Host | Mouse |
| Reactivity | human |
| Form | Liquid |
| Formulation | PBS, Azide |
| Applications | IF/ICC, FC |
| Host / Isotype | Mouse / IgG2a |
| Tested Applications — Positive IF/ICC detected in | hTERT-RPE1 cells |
| Tested Applications — Positive FC detected in | PHA treated human PBMCs |
| Recommended Dilutions — Immunofluorescence (IF)/ICC | IF/ICC : 1:200-1:800 |
| Positive IF/ICC detected in | hTERT-RPE1 cells |
| Positive FC detected in | PHA treated human PBMCs |
| Immunofluorescence (IF)/ICC | IF/ICC : 1:200-1:800 |
| Flow Cytometry (FC) | FC : 0.25 ug per 10^6 cells in 100 μl suspension |
| Tested Reactivity | human |
| Class | Recombinant |
| Type | Antibody |
| Immunogen | Cultured human thymic epithelial cells Predict reactive species |
| Full Name | activated leukocyte cell adhesion molecule |
| Calculated Molecular Weight | 105 kDa |
| GenBank Accession Number | BC057809 |
| Gene Symbol | ALCAM |
| Gene ID (NCBI) | 214 |
| RRID | AB_3670358 |
| Conjugate | Unconjugated |
| Purification Method | Protein A purification |
| UNIPROT ID | Q13740 |
| Storage Buffer | PBS with 0.09% sodium azide, pH 7.3. |
| Storage Conditions | Store at 2-8°C. Stable for one year after shipment. |
| FC protocol for ALCAM antibody 65611-1-MR | Download protocol |
| IF protocol for ALCAM antibody 65611-1-MR | Download protocol |
| Citations | - |
| Dilutions | IF/ICC : 1:200-1:800 |
| Isotype | IgG2a |
| Clonality | Recombinant |
| Clone Number | 3A6 |
| Conjugation | Unconjugated |
Activated leukocyte cell adhesion molecule (ALCAM, also known as CD166) is a cell adhesion molecule that belongs to the immunoglobulin superfamily. It is involved in cell-cell adhesion through homophilic and heterophilic (to CD6) interactions. ALCAM is widely expressed in a variety of normal tissues and cell types, including activated T cells and monocytes, epithelial cells, fibroblasts, neuronal cells, hepatocytes, and bone marrow mesenchymal stem cells (PMID: 7760007; 25221999). Altered ALCAM expression has been associated with the differentiation state and progression in some neoplasms including melanoma, prostate, colorectal, and breast cancers (PMID: 20461761; 18172759). Protocols Product Specific Protocols FC protocol for ALCAM antibody 65611-1-MR Download protocol IF protocol for ALCAM antibody 65611-1-MR Download protocol Standard Protocols Click here to view our Standard Protocols
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