Anti-Human CD11c (BU15) Mouse IgG2a Recombinant Antibody 65600-1-MR proteintech
$67.00
In stock
SKU
65600-1-MR
| Catalog Number | 65600-1-MR |
| Synonyms | BU15, CD11 antigen-like family member C, Integrin alpha X, Integrin alpha-X, ITGAX |
| Host | Mouse |
| Reactivity | human |
| Form | Liquid |
| Formulation | PBS, Azide |
| Applications | FC |
| Host / Isotype | Mouse / IgG2a |
| Tested Applications — Positive FC detected in | human peripheral blood leukocytes |
| Positive FC detected in | human peripheral blood leukocytes |
| Flow Cytometry (FC) | FC : 0.25 ug per 10^6 cells in 100 μl suspension |
| Tested Reactivity | human |
| Class | Recombinant |
| Type | Antibody |
| Immunogen | Human synovial fluid dendritic cells Predict reactive species |
| Full Name | integrin, alpha X (complement component 3 receptor 4 subunit) |
| Calculated Molecular Weight | 1169 aa, 129 kDa |
| GenBank Accession Number | BC038237 |
| Gene Symbol | CD11c |
| Gene ID (NCBI) | 3687 |
| ENSEMBL Gene ID | ENSG00000140678 |
| RRID | AB_3670347 |
| Conjugate | Unconjugated |
| Purification Method | Protein A purification |
| UNIPROT ID | P20702 |
| Storage Buffer | PBS with 0.09% sodium azide, pH 7.3. |
| Storage Conditions | Store at 2-8°C. Stable for one year after shipment. |
| FC protocol for CD11c antibody 65600-1-MR | Download protocol |
| Citations | - |
| Isotype | IgG2a |
| Clonality | Recombinant |
| Clone Number | BU15 |
| Conjugation | Unconjugated |
Integrins are cell adhesion receptors that are heterodimers composed of non-covalently associated α and β subunits (PMID: 9779984). CD11c, also known as integrin αX, is a type I transmembrane glycoprotein present on a variety of cells, including monocytes/macrophages, granulocytes, a subset of B cells, NK cells and dendritic cells (PMID: 2897326; 1680915; 1694698; 17389580). As a result of its high level of expression on most dendritic cells, CD11c is typically considered to be a marker of conventional dendritic cells (PMID: 27119555). CD11c forms an α/β heterodimer with CD18 (integrin β2). CD11c/CD18 acts as a receptor for fibrinogen and is important in monocyte adhesion and chemotaxis (PMID: 1671533). Protocols Product Specific Protocols FC protocol for CD11c antibody 65600-1-MR Download protocol Standard Protocols Click here to view our Standard Protocols
Product Documents
Reviews
Write Your Own Review