CoraLux™ Violet 510 Anti-Mouse MHC Class II (I-A/I-E) (M5/114.15.2) Rat Recombinant Antibody CLV510-65663 proteintech
$257.00
In stock
SKU
CLV510-65663
| Catalog Number | CLV510-65663 |
| Synonyms | H2Aa, Aalpha, H 2Aa, H-2 class II histocompatibility antigen, A-B alpha chain, H2-Aa |
| Host | Rat |
| Reactivity | mouse |
| Form | Liquid |
| Formulation | PBS, Azide |
| Applications | FC |
| Host / Isotype | Rat / IgG2a |
| Tested Applications — Positive FC detected in | mouse splenocytes |
| Positive FC detected in | mouse splenocytes |
| Flow Cytometry (FC) | FC : 0.25 ug per 10^6 cells in a 100 µl suspension |
| Tested Reactivity | mouse |
| Class | Recombinant |
| Type | Antibody |
| Immunogen | N/A Predict reactive species |
| Full Name | histocompatibility 2, class II antigen A, alpha |
| GenBank Accession Number | BC031711 |
| Gene Symbol | MHC Class II |
| Gene ID (NCBI) | 14960 |
| RRID | AB_3749146 |
| Conjugate | CoraLux™ Violet 510 Fluorescent Dye |
| Excitation/Emission Maxima Wavelengths | 408 nm / 496 nm |
| Excitation Laser | Violet Laser (405 nm) |
| Purification Method | Protein A purification |
| UNIPROT ID | P14434 |
| Storage Buffer | PBS with 0.09% sodium azide, pH 7.3. |
| Storage Conditions | Store at 2-8°C. Avoid exposure to light. Stable for one year after shipment. |
| FC protocol for CoraLux™ Violet 510 MHC Class II (I-A/I-E) antibody CLV510-65663 | Download protocol |
| Citations | - |
| Isotype | IgG2a |
| Clonality | Recombinant |
| Clone Number | M5/114.15.2 |
| Conjugation | CoraLux™ Violet 510 |
Major histocompatibility complex (MHC) class II molecules are heterodimeric transmembrane glycoproteins that are expressed on the surface of antigen-presenting cells such as dendritic cells, macrophages, and B cells. The M5/114.15.2 antibody detects polymorphic determinants present on B cells, monocytes, macrophages, dendritic cells, and activated T lymphocytes from mice carrying the H-2b, H-2d, H-2q, H-2p, H-2r and H-2u haplotypes but not from mice carrying the H-2s or H-2f haplotypes (PMID: 6170707). This antibody recognizes both I-A and I-E subregion-encoded Ia glycoproteins (I-Ab, I-Ad, I-Aq, I-Ed, I-Ek, not I-Af, I-Ak, or I-As). M5/114 antibody is reported to inhibit I-A subregion-restricted T cell responses of the H-2b, H-2d, H-2q, H-2u but not the H-2f, H-2k, H-2s haplotypes (PMID: 6173436). Protocols Product Specific Protocols FC protocol for CoraLux™ Violet 510 MHC Class II (I-A/I-E) antibody CLV510-65663 Download protocol Standard Protocols Click here to view our Standard Protocols
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