Anti-Human ICOSLG/B7-H2/CD275 Rabbit Recombinant Antibody 98358-1-RR proteintech
$67.00
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SKU
98358-1-RR
| Catalog Number | 98358-1-RR |
| Synonyms | B7H2, ICOSLG, B7 H2, B7-like protein Gl50, B7-related protein 1 |
| Host | Rabbit |
| Reactivity | human |
| Form | Liquid |
| Formulation | PBS, Azide |
| Applications | FC |
| Host / Isotype | Rabbit / IgG |
| Tested Applications — Positive FC detected in | human monocyte-derived mature dendritic cells |
| Positive FC detected in | human monocyte-derived mature dendritic cells |
| Flow Cytometry (FC) | FC : 0.25 ug per 10^6 cells in 100 μl suspension |
| Tested Reactivity | human |
| Class | Recombinant |
| Type | Antibody |
| Immunogen | CatNo: Eg0008 Product name: Recombinant Human ICOSLG/B7-H2/CD275 protein (Myc Tag, His Tag) Source: mammalian cells -derived, pHZ-KIsec Tag: Myc & 6*His Domain: 19-256 aa of BC064637 Sequence: DTQEKEVRAMVGSDVELSCACPEGSRFDLNDVYVYWQTSESKTVVTYHIPQNSSLENVDSRYRNRALMSPAGMLRGDFSLRLFNVTPQDEQKFHCLVLSQSLGFQEVLSVEVTLHVAANFSVPVVSAPHSPSQDELTFTCTSINGYPRPNVYWINKTDNSLLDQALQNDTVFLNMRGLYDVVSVLRIARTPSVNIGCCIENVLLQQNLTVGSQTGNDIGERDKITENPVSTGEKNAAT Predict reactive species |
| Full Name | inducible T-cell co-stimulator ligand |
| Calculated Molecular Weight | 33 kDa, 34 kDa |
| GenBank Accession Number | BC064637 |
| Gene Symbol | ICOSLG |
| Gene ID (NCBI) | 23308 |
| RRID | AB_3746008 |
| Conjugate | Unconjugated |
| Purification Method | Protein A purification |
| UNIPROT ID | O75144 |
| Storage Buffer | PBS with 0.09% sodium azide, pH 7.3. |
| Storage Conditions | Store at 2 - 8°C. Stable for one year after shipment. |
| FC protocol for ICOSLG/B7-H2/CD275 antibody 98358-1-RR | Download protocol |
| Citations | - |
| Isotype | IgG |
| Clonality | Recombinant |
| Clone Number | 242241C8 |
| Conjugation | Unconjugated |
ICOSLG, also known as B7H2 or GL50, is a type I transmembrane glycoprotein belonging to the B7 ligand family. ICOSLG is extensively expressed on professional antigen-presenting cells including B cells, macrophages, and dendritic cells, as well as non-lymphoid cells including mesenchymal stem cells, endothelial cells, fibroblasts, and tumor cells (PMID: 33756276; 35800767). It is a specific ligand for the T-cell-specific cell surface receptor ICOS and acts as a co-stimulatory molecule (PMID: 11023515; 11007762). The interaction of ICOSLG and ICOS plays important roles in the activation, proliferation, differentiation, and cytokine production of T cells as well as in the antibody secretion from B cells during secondary immune responses (PMID: 21851236). Protocols Product Specific Protocols FC protocol for ICOSLG/B7-H2/CD275 antibody 98358-1-RR Download protocol Standard Protocols Click here to view our Standard Protocols
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