PFKM Polyclonal antibody 55028-1-AP proteintech
$149.00
In stock
SKU
55028-1-AP
| Catalog Number | 55028-1-AP |
| Synonyms | 6-phosphofructokinase type A, ATP-dependent 6-phosphofructokinase, muscle type, ATP-PFK, EC:2.7.1.11, PFK A |
| Host | Rabbit |
| Reactivity | human, mouse, rat and More (4) |
| Reactivity | human, mouse, rat, pig, chicken, bovine, sheep |
| Form | Liquid |
| Formulation | PBS, Azide, Glycerol |
| Applications | WB, IHC, IF/ICC, IP, CoIP, ELISA |
| Applications | WB, IHC, IF/ICC, IP, ELISA |
| Host / Isotype | Rabbit / IgG |
| Tested Applications — Positive WB detected in | HeLa cells, HEK-293 cells, HepG2 cells, human brain tissue, human skeletal muscle tissue, L02 cells, mouse heart tissue, rat heart tissue |
| Tested Applications — Positive IP detected in | mouse liver tissue |
| Tested Applications — Positive IHC detected in | mouse skeletal muscle tissue, human skeletal muscle tissue, mouse brain tissue Note: suggested antigen retrieval with TE buffer pH 9.0; (*) Alternatively, antigen retrieval may be performed with citrate buffer pH 6.0 |
| Tested Applications — Positive IF/ICC detected in | HeLa cells |
| Recommended Dilutions — Western Blot (WB) | WB : 1:2000-1:16000 |
| Recommended Dilutions — Immunoprecipitation (IP) | IP : 0.5-4.0 ug for 1.0-3.0 mg of total protein lysate |
| Recommended Dilutions — Immunohistochemistry (IHC) | IHC : 1:1000-1:4000 |
| Recommended Dilutions — Immunofluorescence (IF)/ICC | IF/ICC : 1:200-1:800 |
| Positive WB detected in | HeLa cells, HEK-293 cells, HepG2 cells, human brain tissue, human skeletal muscle tissue, L02 cells, mouse heart tissue, rat heart tissue |
| Positive IP detected in | mouse liver tissue |
| Positive IHC detected in | mouse skeletal muscle tissue, human skeletal muscle tissue, mouse brain tissue Note: suggested antigen retrieval with TE buffer pH 9.0; (*) Alternatively, antigen retrieval may be performed with citrate buffer pH 6.0 |
| Positive IF/ICC detected in | HeLa cells |
| Western Blot (WB) | WB : 1:2000-1:16000 |
| Immunoprecipitation (IP) | IP : 0.5-4.0 ug for 1.0-3.0 mg of total protein lysate |
| Immunohistochemistry (IHC) | IHC : 1:1000-1:4000 |
| Immunofluorescence (IF)/ICC | IF/ICC : 1:200-1:800 |
| Tested Reactivity | human, mouse, rat |
| Cited Reactivity | human, mouse, rat, pig, chicken, bovine, sheep |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Peptide Predict reactive species |
| Full Name | phosphofructokinase, muscle |
| Calculated Molecular Weight | 85 kDa |
| Observed Molecular Weight | 75-85 kDa |
| GenBank Accession Number | NM_000289 |
| Gene Symbol | PFKM |
| Gene ID (NCBI) | 5213 |
| RRID | AB_10858390 |
| Conjugate | Unconjugated |
| Purification Method | Antigen affinity purification |
| UNIPROT ID | P08237 |
| Storage Buffer | PBS with 0.02% sodium azide and 50% glycerol, pH 7.3. |
| Storage Conditions | Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20 o C storage. 20ul sizes contain 0.1% BSA. |
| IF protocol for PFKM antibody 55028-1-AP | Download protocol |
| IHC protocol for PFKM antibody 55028-1-AP | Download protocol |
| IP protocol for PFKM antibody 55028-1-AP | Download protocol |
| WB protocol for PFKM antibody 55028-1-AP | Download protocol |
| human | WB Nat Cell Biol Fructose-1,6-bisphosphate couples glycolytic activity to cell adhesion. Authors - Lennart Hoffmann View Article |
| mouse,human | WB Cell Metab Astrocytic LRP1 enables mitochondria transfer to neurons and mitigates brain ischemic stroke by suppressing ARF1 lactylation Authors - Jian Zhou View Article |
| Citations | 122 |
| Dilutions | WB : 1:2000-1:16000 IP : 0.5-4.0 ug for IP and 0.5-4.0 ug for 1.0-3.0 mg of total protein lysate for WB IHC : 1:1000-1:4000 IF/ICC : 1:200-1:800 |
| Isotype | IgG |
| Clonality | Polyclonal |
| Clone Number | - |
| Conjugation | Unconjugated |
PFKM, also named as GSD7, PFK-1, PFK-M and PFKX, belongs to the phosphofructokinase family and two domains subfamily. PFKM catalyzes the reaction: ATP + D-fructose 6-phosphate = ADP + D-fructose 1,6-bisphosphate. It is a key regulatory enzyme in glycolysis. Defects in PFKM are the cause of glycogen storage disease type 7 (GSD7). PFKM has three isoforms with molecular masses of 85, 82 and 93 kDa. The antibody is specific to PFKM. Protocols Product Specific Protocols IF protocol for PFKM antibody 55028-1-AP Download protocol IHC protocol for PFKM antibody 55028-1-AP Download protocol IP protocol for PFKM antibody 55028-1-AP Download protocol WB protocol for PFKM antibody 55028-1-AP Download protocol Standard Protocols Click here to view our Standard Protocols
Publications
- Mechanical regulation of glycolysis via cytoskeleton architecture.
Journal: Nature | Authors: Jin Suk Park | Species: human | Application: WB - The diapause-like colorectal cancer cells induced by SMC4 attenuation are characterized by low proliferation and chemotherapy insensitivity
Journal: Cell Metab | Authors: Xuedan Sun | Species: mouse,human | Application: WB - Astrocytic LRP1 enables mitochondria transfer to neurons and mitigates brain ischemic stroke by suppressing ARF1 lactylation
Journal: Cell Metab | Authors: Jian Zhou | Species: mouse,human | Application: WB - Mannose antagonizes GSDME-mediated pyroptosis through AMPK activated by metabolite GlcNAc-6P
Journal: Cell Res | Authors: Yuan-Li Ai | Species: human | Application: WB - A large-scale targeted proteomics assay resource based on an in vitro human proteome.
Journal: Nat Methods | Authors: Masaki Matsumoto | Species: human | Application: WB - Fructose-1,6-bisphosphate couples glycolytic activity to cell adhesion.
Journal: Nat Cell Biol | Authors: Lennart Hoffmann | Species: human | Application: WB - Disrupting Circadian Rhythm via the PER1-HK2 Axis Reverses Trastuzumab Resistance in Gastric Cancer.
Journal: Cancer Res | Authors: Jiao Wang | Species: human | Application: WB - Exon Skipping of Ste20-Like Kinase Enhances Glycolysis and Tumor Progression by Activating Enolase 1-Mediated Phosphoenolpyruvate Production
Journal: Cancer Res | Authors: Zeyu Chen - A glycolytic shift in Schwann cells supports injured axons.
Journal: Nat Neurosci | Authors: Elisabetta Babetto | Species: mouse | Application: IF - Matrix stiffness regulates nucleus pulposus cell glycolysis by MRTF-A-dependent mechanotransduction
Journal: Bone Res | Authors: Haoran Xu | Species: rat,human | Application: WB,IHC - Pyruvate metabolism enzyme Dlat induces mitochondria protein hyperacetylation to limit fatty acid oxidation in the HFpEF heart.
Journal: Nat Commun | Authors: Ying Wang | Species: mouse | Application: WB - PFKM phosphorylates histone H3 and promotes mitotic progression by sensing the levels of citrate.
Journal: Nat Commun | Authors: Pianpian Lin | Species: human | Application: WB,IP,CoIP - Pyruvate metabolism enzyme Dlat induces mitochondria protein hyperacetylation to limit fatty acid oxidation in the HFpEF heart.
Journal: Nat Commun | Authors: Ying Wang | Species: mouse | Application: WB - Protein kinase N1 deficiency results in upregulation of cerebral energy metabolism and is highly protective in in vivo and in vitro stroke models
Journal: Metabolism | Authors: Stephanie Zur Nedden | Species: mouse | Application: WB - Glucagon-like peptide-1 receptor signaling activation in alveolar type II cells enhances lung development in neonatal rats exposed to hyperoxia
Journal: Redox Biol | Authors: Tong Sun | Species: rat | Application: WB - Porcine epidemic diarrhea virus promotes viral replication via ROS/HIF-1α-mediated glycolysis.
Journal: Redox Biol | Authors: Yafang Xu | Species: pig | Application: WB - Determinants of the maximal functional reserve during repeated supramaximal exercise by humans: The roles of Nrf2/Keap1, antioxidant proteins, muscle phenotype and oxygenation
Journal: Redox Biol | Authors: Victor Galvan-Alvarez | Species: human | Application: WB - Lactate metabolism is essential in early-onset mitochondrial myopathy
Journal: Sci Adv | Authors: Zhenkang Chen | Species: mouse | Application: WB - Liver-targeted Nano-MitoPBN normalizes glucose metabolism by improving mitochondrial redox balance.
Journal: Biomaterials | Authors: Meiling Wu | Species: human | Application: WB - Chicoric acid targets PYGL to normalize glycogenolysis-driven glycolysis to suppress non-small cell lung cancer.
Journal: Cell Mol Biol Lett | Authors: Xingfa Huo - RB1 controls differentiation through positive regulation of phosphoglycerate mutases
Journal: Cell Death Dis | Authors: Susumu Kohno | Species: mouse | Application: WB - The role of S-nitrosylation of PFKM in regulation of glycolysis in ovarian cancer cells.
Journal: Cell Death Dis | Authors: Wenwen Gao | Species: mouse | Application: WB - m(6)A demethylase FTO drives pancreatic ductal adenocarcinoma tumorigenesis and metastasis through remodeling PFKM mediated glycolysis.
Journal: Cell Death Dis | Authors: Zhen Tan | Species: mouse,human | Application: WB,IF - Hypoxia-induced ALDH3A1 promotes the proliferation of non-small-cell lung cancer by regulating energy metabolism reprogramming
Journal: Cell Death Dis | Authors: Yang Chen | Species: human | Application: WB - Curcumol Induces Necroptosis of Hepatic Stellate Cells by Targeting KAT8 to Suppress HK2 Lactylation and Promote HUWE1-Dependent Ubiquitination.
Journal: Int J Biol Sci | Authors: Xiaohan Guo | Species: mouse,human | Application: WB - Targeting HLA-F suppresses the proliferation of glioma cells via a reduction in hexokinase 2-dependent glycolysis.
Journal: Int J Biol Sci | Authors: Xin Chen | Species: mouse | Application: WB - Dual-mechanistic regulation of podocyte pyroptosis in lupus nephritis by the AP-1 complex: transcriptional activation of NLRP3 and lactate-mediated ubiquitination inhibition.
Journal: Cell Commun Signal | Authors: Pei-lei Chen | Species: mouse,human | Application: WB - Astragaloside IV alleviates radiation-induced heart disease by regulating energy metabolism
Journal: Phytomedicine | Authors: Qiyang Li - Paeoniflorin ameliorates airway inflammation and immune response in ovalbumin induced asthmatic mice: From oxidative stress to autophagy.
Journal: Phytomedicine | Authors: Xin Han | Species: mouse | Application: WB - RPLP2 activates TLR4 in an autocrine manner and promotes HIF-1α-induced metabolic reprogramming in hepatocellular carcinoma
Journal: Cell Death Discov | Authors: Qingqing Yang | Species: human | Application: WB - TDP-43 impairs glycolysis by sequestering hexokinase 1 in amyotrophic lateral sclerosis.
Journal: Acta Neuropathol | Authors: Cassandra Barone | Species: mouse,human | Application: WB,IF - SEMA5B depletion suppresses cell proliferation and glycolysis by downregulating VDAC2 expression in esophageal squamous cell carcinoma.
Journal: Int J Biol Macromol | Authors: Caifeng Zhang | Species: human | Application: WB - PKM2 alleviates mitochondrial oxidative stress and neuronal apoptosis through metabolic and non-metabolic pathways to protect SOD1G93A mice
Journal: Free Radic Biol Med | Authors: Zhuo Zhang | Species: mouse | Application: WB - Glutaredoxins concomitant with optimal ROS activate AMPK through S-glutathionylation to improve glucose metabolism in type 2 diabetes.
Journal: Free Radic Biol Med | Authors: Kelei Dong | Species: human | Application: WB - Acox1 induces lipid peroxidation and metabolic shifting to promote PASMCs proliferation in hypoxia-induced pulmonary hypertension.
Journal: Free Radic Biol Med | Authors: Qi Liang | Species: rat,mouse | Application: WB,IHC,IF - A Photoannealed Granular Hydrogel Facilitating Hyaline Cartilage Regeneration via Improving Chondrogenic Phenotype
Journal: ACS Appl Mater Interfaces | Authors: Yu Zhu | Species: mouse | Application: WB - Protein lactylation of citrate synthase promotes the AKI-CKD transition by activating the NLRP3 inflammasome
Journal: Cell Rep | Authors: Fang Yu | Species: mouse | Application: WB - AMPK regulates homeostasis of invasion and viability in trophoblasts by redirecting glucose metabolism: Implications for pre-eclampsia
Journal: Cell Prolif | Authors: Ping Xu | Species: mouse | Application: WB - Emodin promotes hepatic stellate cell senescence and alleviates liver fibrosis via Nur77-mediated epigenetic regulation of GLS1
Journal: Br J Pharmacol | Authors: Li Chen | Species: human | Application: WB - Huangqi-Danshen decoction reshapes renal glucose metabolism profiles that delays chronic kidney disease progression
Journal: Biomed Pharmacother | Authors: Xi Huang | Species: mouse | Application: WB,IF - Buyang Huanwu Decoction improves energy metabolism disorders after cerebral ischemia-reperfusion by regulating the SIRT1/AMPK signaling pathway to promote glycolysis and the tricarboxylic acid cycle
Journal: Chin Med | Authors: Zhongji Hu | Species: rat | Application: WB - Mild Hypothermia Attenuates Hepatic Ischemia-Reperfusion Injury through Regulating the JAK2/STAT3-CPT1a-Dependent Fatty Acid β-Oxidation.
Journal: Oxid Med Cell Longev | Authors: Wei Wang | Species: mouse | Application: WB - Click RNA for Rapid Capture and Identification of Intracellular MicroRNA Targets.
Journal: Anal Chem | Authors: Pengjuan Zhang | Species: human | Application: WB - GCN5-mediated PKM2 acetylation participates in benzene-induced hematotoxicity through regulating glycolysis and inflammation via p-Stat3/IL17A axis.
Journal: Environ Pollut | Authors: Wei Zhang | Species: mouse | Application: WB,IP - USP7 facilitates brain tumor survival upon glucose deprivation by regulating phosphofructokinase muscle-type nuclear translocation in mice.
Journal: PLoS Biol | Authors: Siyang Wu | Species: human | Application: IHC - Effects of Dahuang zhechong pill on doxorubicin-resistant SMMC-7721 xenografts in mice.
Journal: J Ethnopharmacol | Authors: Li Wu | Species: human | Application: WB - The alterations of miRNA and mRNA expression profile and their integration analysis induced by silica nanoparticles in spermatocyte cells.
Journal: NanoImpact | Authors: Guiqing Zhou | Species: mouse | Application: WB - Knockdown of SESN2 Exacerbates Cerebral Ischemia-Reperfusion Injury Through Enhancing Glycolysis via the mTOR/HIF-1α Pathway
Journal: CNS Neurosci Ther | Authors: Zhihui Wang | Species: mouse | Application: WB - Juglone targets MMP-1 to inhibit gastric cancer progression
Journal: Biochem Pharmacol | Authors: Fanghui Zhou | Application: WB - The glycolytic enzyme PFKM promotes renal fibrosis by activating the NF-κB pathway via lactate-mediated H3K18 lactylation.
Journal: Cell Mol Life Sci | Authors: Yizhen Chen | Species: mouse,human | Application: WB,IHC,IF - WTAP upregulates HK2 expression via m6A methylation to reprogram cell glycolysis and stemness under Cr(VI) exposure.
Journal: J Environ Sci (China) | Authors: Yunxia Xie - L-Theanine affects intestinal mucosal immunity by regulating short-chain fatty acid metabolism under dietary fiber feeding.
Journal: Food Funct | Authors: Wei Xu | Species: rat | Application: WB - Metabolic plasticity and optimal redox homeostasis are essential for efficient metastatic colonization.
Journal: Mol Metab | Authors: Ece Grace | Species: mouse | Application: WB - The Metabolic Changes between Monolayer (2D) and Three-Dimensional (3D) Culture Conditions in Human Mesenchymal Stem/Stromal Cells Derived from Adipose Tissue
Journal: Cells | Authors: Paulina Rybkowska | Species: human | Application: WB - The Metabolic Changes between Monolayer (2D) and Three-Dimensional (3D) Culture Conditions in Human Mesenchymal Stem/Stromal Cells Derived from Adipose Tissue
Journal: Cells | Authors: Paulina Rybkowska | Species: human | Application: WB - Coxsackievirus B3 infection induces glycolysis to facilitate viral replication
Journal: Front Microbiol | Authors: Yujie Qian | Species: rat,mouse | Application: WB - Activated DRP1 promotes mitochondrial fission and induces glycolysis in ATII cells under hyperoxia
Journal: Respir Res | Authors: Tong Sun | Species: rat | Application: WB - Exosome-Related FTCD Facilitates M1 Macrophage Polarization and Impacts the Prognosis of Hepatocellular Carcinoma
Journal: Biomolecules | Authors: Youyi Liu | Species: mouse | Application: WB - Integrated Multilayer Omics Reveals the Underlying Mechanisms in Xylazine-Related Heart Injury in Rats.
Journal: Int J Mol Sci | Authors: Yangchang Ou | Species: rat | Application: WB - Aspirin induces immunogenic cell death and enhances cancer immunotherapy in colorectal cancer
Journal: Int Immunopharmacol | Authors: Jun Lei | Species: human | Application: WB - Exosome-Related FTCD Facilitates M1 Macrophage Polarization and Impacts the Prognosis of Hepatocellular Carcinoma
Journal: Biomolecules | Authors: Youyi Liu | Species: mouse | Application: WB - Fenofibrate Differently Affects the Heart's Morphology and Metabolism in Young and Old Rats
Journal: Int J Mol Sci | Authors: Agata Wrońska | Application: WB - IL17A Mediates Glycolysis-Dependent Primary Angiogenesis and Exacerbates Ischemic Stroke Injury.
Journal: Mol Neurobiol | Authors: Qingxue Xu | Species: mouse | Application: WB - Relocation of phosphofructokinases within epithelial cells is a novel event preceding breast cancer recurrence that accurately predicts patient outcomes.
Journal: Am J Physiol Cell Physiol | Authors: Richard A Cheung | Species: human - Ectopic endometriotic stromal cells-derived lactate induces M2 macrophage polarization via Mettl3/Trib1/ERK/STAT3 signaling pathway in endometriosis
Journal: Immunology | Authors: Yanling Gou | Species: human | Application: IHC - CDC5L drives FAH expression to promote metabolic reprogramming in melanoma.
Journal: Oncotarget | Authors: Zhichao Gu | Species: human | Application: WB - Myostatin Mutation Promotes Glycolysis by Increasing Phosphorylation of Phosphofructokinase via Activation of PDE5A-cGMP-PKG in Cattle Heart.
Journal: Front Cell Dev Biol | Authors: Mingjuan Gu | Species: bovine | Application: WB - Study on the mechanisms of defective spermatogenesis induced by TiO2 NPs based on 3D blood-testis barrier microfluidic chip
Journal: Toxicology | Authors: Ruoyun Dong | Species: mouse | Application: WB - Dietary pectin and inulin: a promising adjuvant supplement for collagen-induced arthritis through gut microbiome restoration and CD4+ T cell reconstitution
Journal: J Nutr Biochem | Authors: Yu Lou | Species: mouse | Application: WB - High salt diet induces metabolic alterations in multiple biological processes of Dahl salt-sensitive rats.
Journal: J Nutr Biochem | Authors: Yanjun Wang | Species: rat | Application: WB - Synthesis and biological evaluation of novel 5,6,7-trimethoxy flavonoid salicylate derivatives as potential anti-tumor agents.
Journal: Bioorg Chem | Authors: Renbo Liu | Species: human | Application: WB - The platelet isoform of phosphofructokinase contributes to metabolic reprogramming and maintains cell proliferation in clear cell renal cell carcinoma.
Journal: Oncotarget | Authors: Jun Wang | Species: human | Application: WB - Baicalein suppresses inflammation and attenuates acute lung injury by inhibiting glycolysis via HIF‑1α signaling
Journal: Mol Med Rep | Authors: Zhongyou Liu | Species: mouse | Application: IHC - Cancer-Associated fibroblasts regulate the development of cholangiocarcinoma through IL-6/STAT3/AKR1C3 signaling axis.
Journal: Sci Rep | Authors: Tian-cong Huang | Species: human | Application: WB - Lactate reprograms PGE2 metabolism via GPR81 inhibits COX2 to relieved psoriasis.
Journal: Sci Rep | Authors: Yajun An | Species: mouse | Application: WB - Activation of M1 macrophages promotes diabetic kidney disease by modulating glycolysis via HIF-1α-HK2 signaling pathway
Journal: Diabetol Metab Syndr | Authors: Xiaoyan Pei | Species: human | Application: WB - Radiation-induced changes in energy metabolism result in mitochondrial dysfunction in salivary glands
Journal: Sci Rep | Authors: Lauren G Buss | Species: mouse | Application: WB - TSZAF Monomer Combination Inhibits the Progression of Ovarian Cancer Via Regulating the AKT/FOXO3A-mediated Glycolysis Pathway.
Journal: Biol Proced Online | Authors: Long Zhang | Species: human | Application: WB - Redox homeostasis protects mitochondria through accelerating ROS conversion to enhance hypoxia resistance in cancer cells.
Journal: Sci Rep | Authors: Pengying Li | Species: human | Application: WB - Activation of M1 macrophages promotes diabetic kidney disease by modulating glycolysis via HIF-1α-HK2 signaling pathway
Journal: Diabetol Metab Syndr | Authors: Xiaoyan Pei | Species: human | Application: WB - Radiation-induced changes in energy metabolism result in mitochondrial dysfunction in salivary glands
Journal: Sci Rep | Authors: Lauren G Buss | Species: mouse | Application: WB - UCHL1-mediated deubiquitination of GLOD4 regulates mitochondrial homeostasis and PTC malignant progression via GLO1.
Journal: Mol Cell Biochem | Authors: Lei Cai | Species: human | Application: WB - Tripartite-motif 3 represses ovarian cancer progression by downregulating lactate dehydrogenase A and inhibiting AKT signaling
Journal: Mol Cell Biochem | Authors: Yu Cong | Species: human | Application: WB - Multi-Omics Landscape of Paraspinal Muscles in Spinal Muscular Atrophy With Scoliosis.
Journal: J Cell Mol Med | Authors: Zhen Wang - Untargeted Metabolomics Reveals Effects of Calorie Restriction on Skeletal Muscle in Older Female and Male Rats.
Journal: J Gerontol A Biol Sci Med Sci | Authors: Haiyan Wang | Species: rat | Application: WB - Aging is associated with impaired postprandial response of skeletal muscle protein synthesis to high-intensity muscle contraction in mice
Journal: J Gerontol A Biol Sci Med Sci | Authors: Satoru Ato | Species: mouse | Application: WB - USP5-mediated CD73 deubiquitination drives osimertinib resistance via PI3K/AKT and glycolysis activation in LUAD.
Journal: iScience | Authors: Rui Chen | Species: human | Application: WB - GL-V9 inhibits the activation of AR-AKT-HK2 signaling networks and induces prostate cancer cell apoptosis through mitochondria-mediated mechanism
Journal: iScience | Authors: Rui Wang | Species: human | Application: WB - Effect of chronic heat stress on the carbonylation of glycolytic enzymes in breast muscle and its correlation with the growth performance of broilers
Journal: Poult Sci | Authors: Yingsen Liu | Species: chicken | Application: WB - Lactate facilitates classical swine fever virus replication by enhancing cholesterol biosynthesis
Journal: iScience | Authors: Xiaodong Zou | Species: pig | Application: WB - USP5-mediated CD73 deubiquitination drives osimertinib resistance via PI3K/AKT and glycolysis activation in LUAD.
Journal: iScience | Authors: Rui Chen | Species: human | Application: WB - m6A-mediated regulation of ECA39 promotes renal fibrosis in chronic kidney disease by enhancing glycolysis and epithelial-mesenchymal transition
Journal: Biochim Biophys Acta Mol Cell Res | Authors: Ziyuan Tong | Species: mouse | Application: WB - Activity and function of auxiliary fluxes of glucose metabolism in response to physiological normoxia (5 % O2) during long-term Adipose-Derived Stem/Stromal cell culture
Journal: Eur J Cell Biol | Authors: Paulina Rybkowska | Species: human | Application: WB - Icariin ameliorates glycolytic dysfunction in Alzheimer's disease models by activating the Wnt/β-catenin signaling pathway
Journal: FEBS J | Authors: Ju Liu | Species: mouse | Application: WB - Cyclin D1 extensively reprograms metabolism to support biosynthetic pathways in hepatocytes
Journal: J Biol Chem | Authors: Heng Wu - Physiological and molecular predictors of cycling sprint performance
Journal: Scand J Med Sci Sports | Authors: Victor Galvan-Alvarez | Species: human | Application: WB - LncARSR promotes glioma tumor growth by mediating glycolysis through the STAT3/HK2 axis
Journal: Cytokine | Authors: Zhenyang Tian | Species: human | Application: WB - Proteomic analysis of mouse liver lesions at all three stages of Echinococcus granulosus infection
Journal: PLoS Negl Trop Dis | Authors: Nan Jiang | Species: sheep,mouse | Application: WB - 1,12-cyclic-apelin-12 counters vascular smooth muscle cell proliferation and atherosclerosis through inhibiting aerobic glycolysis.
Journal: Toxicol Appl Pharmacol | Authors: Ruirui Lu - CTPS and IMPDH form cytoophidia in developmental thymocytes.
Journal: Exp Cell Res | Authors: Min Peng | Species: mouse | Application: IF - The drs tumor suppressor regulates glucose metabolism via lactate dehydrogenase-B.
Journal: Mol Carcinog | Authors: Yukihiro Tambe | Species: mouse | Application: WB - High-Fat Diet Promotes Glycolysis in Hepatocellular Carcinoma by Suppressing Hepatic Kisspeptin Signaling in Mice.
Journal: Mol Carcinog | Authors: Rongqian Zhao | Species: mouse,human | Application: WB - High-Fat Diet Promotes Glycolysis in Hepatocellular Carcinoma by Suppressing Hepatic Kisspeptin Signaling in Mice.
Journal: Mol Carcinog | Authors: Rongqian Zhao | Species: mouse,human | Application: WB - SESN2 mediates resistance training-induced improvements in exercise performance and energy metabolism in C57BL/6J mice
Journal: Exp Cell Res | Authors: Yating Huang | Species: mouse | Application: WB - Testosterone differentially regulates targets of lipid and glucose metabolism in liver, muscle and adipose tissues of the testicular feminised mouse.
Journal: Endocrine | Authors: Daniel M Kelly | Species: mouse | Application: WB - Severe early-onset preeclampsia is significantly associated with metabolic dysregulation and sustained elevation of placental HIF-1α.
Journal: Placenta | Authors: Courtney B. Johnson-Gonzalez | Species: human | Application: WB - The Role of PI3K/AKT/HIF-1α Pathway in the Effect of Nano-TiO2 on Lactate Production in TM4 Cells
Journal: J Appl Toxicol | Authors: Hongmei Chang | Species: mouse | Application: WB - Gua Sha Alleviates Radiculitis-Induced Pain Via HIF-1α-Mediated Metabolic Reprogramming Pathway in Rats
Journal: Pain Res Manag | Authors: Haotian Ge | Species: rat | Application: WB - AFP confers the resistance of lenvatinib in hepatocellular carcinoma by activating PI3K/AKT/LDHA signaling axis.
Journal: Discov Oncol | Authors: Weimei Xing | Species: human | Application: WB - Protein recycling and limb muscle recovery after critical illness in slow- and fast-twitch limb muscle.
Journal: Am J Physiol Regul Integr Comp Physiol | Authors: Sebastien Preau | Species: rat | Application: WB - Resveratrol inhibits VEGF-induced angiogenesis in human endothelial cells associated with suppression of aerobic glycolysis via modulation of PKM2 nuclear translocation.
Journal: Clin Exp Pharmacol Physiol | Authors: Hongyan Wu | Species: human | Application: WB - ROS-mediated glucose metabolic reprogram induces insulin resistance in type 2 diabetes.
Journal: Biochem Biophys Res Commun | Authors: Kelei Dong | Species: rat | Application: WB - Energy Metabolism in the Bone is Associated with Histomorphometric Changes in Rats with Hyperthyroidism.
Journal: Cell Physiol Biochem | Authors: Zhuoqing Hu | Species: rat | Application: WB - TXNIP participates in the pathogenesis of PCOS by regulating glycolysis in granulosa cells
Journal: Biochem Biophys Res Commun | Authors: Rongyan Zhu | Species: mouse | Application: WB,IHC - N-nitrosodimethylamine increased glucose production by promoting hyperglycemia in hepatocyte via AMPK signaling pathway in vivo and in vitro.
Journal: Drug Chem Toxicol | Authors: Wenxin Wang | Species: mouse,human | Application: WB - Study on the Antitumor Effect and Glycolysis of Andrographolide in Anaplastic Thyroid Carcinoma.
Journal: Evid Based Complement Alternat Med | Authors: Ke Yang | Species: human | Application: WB - Artemether ameliorates type 1 diabetes mellitus by modulating glycolipid metabolism in skeletal muscle
Journal: Am J Transl Res | Authors: Yifan Dong - Dahuang Zhechong Pill Combined with Doxorubicin Induces Cell Death through Regulating Energy Metabolism in Human Hepatocellular Carcinoma Cells.
Journal: Evid Based Complement Alternat Med | Authors: Li Wu | Species: human | Application: WB - Poly(ADP-ribose) polymerase regulates glycolytic activity in kidney proximal tubule epithelial cells.
Journal: Anat Cell Biol | Authors: Hana Song | Species: pig | Application: WB - Depressed Proximal Glycolysis in Myocardium Of Human Heart Failure with Preserved Ejection Fraction
Journal: medRxiv | Authors: Navid Koleini | Species: human | Application: WB - Radiation-Induced Changes in Energy Metabolism Result in Mitochondrial Dysfunction in Salivary Glands
Journal: bioRxiv | Authors: Lauren G Buss | Species: mouse | Application: WB - Gut microbiota-derived indole-3-propionic acid attenuates Arsenic trioxide-induced cognitive impairment by inhibiting ubiquitination and degradation of BRD4.
Journal: Br J Pharmacol | Authors: Kai Ren - Malate-aspartate shuttle inactivation drives pulmonary hypertension through glucose carbon flux rewiring and α-ketoglutarate-dependent epigenetic remodeling.
Journal: Redox Biol | Authors: Ying Wang | Species: mouse | Application: WB,IF
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