CoraLite® Plus 488-conjugated AATF Monoclonal antibody CL488-67868 proteintech

$479.00
In stock
SKU
CL488-67868
Catalog No.SizePrice (USD)
CL488-67868-100UL100 μL$479.00
Catalog NumberCL488-67868
SynonymsProtein AATF, HSPC277, DED, CHE1, CHE 1
HostMouse
Reactivityhuman, mouse, rat
FormLiquid
FormulationPBS, Proclin300, BSA, Glycerol
ApplicationsFC (Intra)
Host / IsotypeMouse / IgG1
Tested Applications — Positive FC (Intra) detected inHeLa cells
Recommended Dilutions — Flow Cytometry (FC) (INTRA)FC (INTRA) : 0.40 ug per 10^6 cells in a 100 µl suspension
Positive FC (Intra) detected inHeLa cells
Flow Cytometry (FC) (INTRA)FC (INTRA) : 0.40 ug per 10^6 cells in a 100 µl suspension
Tested Reactivityhuman, mouse, rat
ClassMonoclonal
TypeAntibody
ImmunogenCatNo: Ag0195 Product name: Recombinant human AATF protein Source: e coli. -derived, PGEX-4T Tag: GST Domain: 7-212 aa of BC000591 Sequence: LALQLEQLLNPRPSEADPEADPEEATAARVIDRFDEGEDGEGDFLVVGSIRKLASASLLDTDKRYCGKTTSRKAWNEDHWEQTLPGSSDEEISDEEGSGDEDSEGLGLEEYDEDDLGAAEEQECGDHRESKKSRSHSAKTPGFSVQSISDFEKFTKGMDDLGSSEEEEDEESGMEEGDDAEDSQGESEEDRAGDRNSEDDGVVMTF Predict reactive species
Full Nameapoptosis antagonizing transcription factor
Calculated Molecular Weight63 kDa
Observed Molecular Weight80-90 kDa
GenBank Accession NumberBC000591
Gene SymbolAATF
Gene ID (NCBI)26574
RRIDAB_2923810
ConjugateCoraLite® Plus 488 Fluorescent Dye
Excitation/Emission Maxima Wavelengths493 nm / 522 nm
Excitation LaserBlue laser (488 nm)
Purification MethodProtein G purification
UNIPROT IDQ9NY61
Storage BufferPBS with 50% glycerol, 0.05% Proclin300, 0.5% BSA, pH 7.3.
Storage ConditionsStore at -20°C. Avoid exposure to light. Stable for one year after shipment. Aliquoting is unnecessary for -20 o C storage.
FC protocol for CL Plus 488 AATF antibody CL488-67868Download protocol
Citations-
DilutionsFC (INTRA) : 0.40 ug per 10^6 cells in a 100 µl suspension
IsotypeIgG1
ClonalityMonoclonal
Clone Number2A6G6
ConjugationCoraLite® Plus 488

Apoptosis antagonizing transcription factor (AATF), an interacting partner of RNA polymerase II is a multifunctional protein that is highly conserved in eukaryotes. In addition to nuclear hormone receptors, AATF has been shown to interact with several transcription factors, including the retinoblastoma protein (pRb), p65, and STAT3(PMID: 34785906). Furthermore AATF serves as a critical regulator in various cancers and promotes tumorigenesis by protecting cancer cells from apoptosis induction, favoring cell proliferation, or promoting cell survival by autophagy(PMID: 33145763). Protocols Product Specific Protocols FC protocol for CL Plus 488 AATF antibody CL488-67868 Download protocol Standard Protocols Click here to view our Standard Protocols

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