NFIL3 Monoclonal antibody, PBS Only 66368-1-PBS proteintech
$699.00
In stock
SKU
66368-1-PBS
| Catalog Number | 66368-1-PBS |
| Synonyms | Interleukin-3-binding protein 1, Interleukin-3 promoter transcriptional activator, IL3BP1, E4BP4, E4 promoter-binding protein 4 |
| Host | Mouse |
| Reactivity | pig, human |
| Form | Liquid |
| Formulation | PBS Only |
| Applications | ELISA, WB |
| Host / Isotype | Mouse / IgG1 |
| Tested Reactivity | pig, human |
| Class | Monoclonal |
| Type | Antibody |
| Immunogen | CatNo: Ag2380 Product name: Recombinant human NFIL3 protein Source: e coli. -derived, PGEX-4T Tag: GST Domain: 113-462 aa of BC008197 Sequence: ATLKAELLSLKLKFGLISSTAYAQEIQKLSNSTAVYFQDYQTSKSNVSSFVDEHEPSMVSSSCISVIKHSPQSSLSDVSEVSSVEHTQESSVQGSCRSPENKFQIIKQEPMELESYTREPRDDRGSYTASIYQNYMGNSFSGYSHSPPLLQVNRSSSNSPRTSETDDGVVGKSSDGEDEQQVPKGPIHSPVELKHVHATVVKVPEVNSSALPHKLRIKAKAMQIKVEAFDNEFEATQKLSSPIDMTSKRHFELEKHSAPSMVHSSLTPFSVQVTNIQDWSLKSEHWHQKELSGKTQNSFKTGVVEMKDSGYKVSDPENLYLKQGIANLSAEVVSLKRLIATQPISASDSG Predict reactive species |
| Full Name | nuclear factor, interleukin 3 regulated |
| Calculated Molecular Weight | 462 aa, 51 kDa |
| Observed Molecular Weight | 50-55 kDa |
| GenBank Accession Number | BC008197 |
| Gene Symbol | NFIL3 |
| Gene ID (NCBI) | 4783 |
| RRID | AB_2881748 |
| Conjugate | Unconjugated |
| Purification Method | Protein G purification |
| UNIPROT ID | Q16649 |
| Storage Buffer | PBS only, pH 7.3. |
| Storage Conditions | Store at -80°C. |
| Citations | - |
| Isotype | IgG1 |
| Clonality | Monoclonal |
| Clone Number | 2F4B4 |
| Conjugation | Unconjugated |
NFIL3, also named E4BP4 and IL3BP1, belongs to the bZIP family and NFIL3 subfamily. It represses transcription from promoters with activating transcription factor (ATF) sites. NFIL3 activates transcription from the interleukin-3 promoter in T-cells. It competes for the same consensus-binding site with PAR DNA-binding factors (DBP, HLF and TEF). It is a component of the circadian clock that acts as a negative regulator for the circadian expression of PER2 oscillation in the cell-autonomous core clock. NFIL3 protects pro-B cells from programmed cell death. It is a key regulator of TH2 responses(PMID:21499227).
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