ABCD2 Polyclonal antibody 18179-1-AP proteintech
$149.00
In stock
SKU
18179-1-AP
| Catalog Number | 18179-1-AP |
| Synonyms | ABCD 2, Adrenoleukodystrophy-like 1, Adrenoleukodystrophy-related protein, ALDRP, ATP-binding cassette sub-family D member 2 |
| Host | Rabbit |
| Reactivity | human, mouse, rat |
| Form | Liquid |
| Formulation | PBS, Azide, Glycerol |
| Applications | WB, IHC, IP, ELISA |
| Host / Isotype | Rabbit / IgG |
| Tested Applications — Positive WB detected in | mouse adipose tissue, mouse cerebellum tissue, rat adipose tissue |
| Tested Applications — Positive IP detected in | mouse adipose tissue |
| Tested Applications — Positive IHC detected in | mouse brain tissue Note: suggested antigen retrieval with TE buffer pH 9.0; (*) Alternatively, antigen retrieval may be performed with citrate buffer pH 6.0 |
| Recommended Dilutions — Western Blot (WB) | WB : 1:1000-1:8000 |
| Recommended Dilutions — Immunoprecipitation (IP) | IP : 0.5-4.0 ug for 1.0-3.0 mg of total protein lysate |
| Recommended Dilutions — Immunohistochemistry (IHC) | IHC : 1:200-1:800 |
| Positive WB detected in | mouse adipose tissue, mouse cerebellum tissue, rat adipose tissue |
| Positive IP detected in | mouse adipose tissue |
| Positive IHC detected in | mouse brain tissue Note: suggested antigen retrieval with TE buffer pH 9.0; (*) Alternatively, antigen retrieval may be performed with citrate buffer pH 6.0 |
| Western Blot (WB) | WB : 1:1000-1:8000 |
| Immunoprecipitation (IP) | IP : 0.5-4.0 ug for 1.0-3.0 mg of total protein lysate |
| Immunohistochemistry (IHC) | IHC : 1:200-1:800 |
| Tested Reactivity | human, mouse, rat |
| Cited Reactivity | human, mouse |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | CatNo: Ag12872 Product name: Recombinant human ABCD2 protein Source: e coli. -derived, PGEX-4T Tag: GST Domain: 371-740 aa of BC104901 Sequence: ADGEDGQKQVMVSERTEAFTTARNLLASGADAIERIMSSYKEVTELAGYTARVYNMFWVFDEVKRGIYKRTAVIQESESHSKNGAKVELPLSDTLAIKGKVIDVDHGIICENVPIITPAGEVVASRLNFKVEEGMHLLITGPNGCGKSSLFRILSGLWPVYEGVLYKPPPQHMFYIPQRPYMSLGSLRDQVIYPDSVDDMHDKGYTDQDLERILHNVHLYHIVQREGGWDAVMDWKDVLSGGEKQRMGMARMFYHKPKYALLDECTSAVSIDVEGKIFQAAKGAGISLLSITHRPSLWKYHTHLLQFDGEGGWRFEQLDTAIRLTLSEEKQKLESQLAGIPKMQQRLNELCKILGEDSVLKTIKNEDETS Predict reactive species |
| Full Name | ATP-binding cassette, sub-family D (ALD), member 2 |
| Calculated Molecular Weight | 740 aa, 83 kDa |
| Observed Molecular Weight | 70-75 kDa |
| GenBank Accession Number | BC104901 |
| Gene Symbol | ABCD2 |
| Gene ID (NCBI) | 225 |
| RRID | AB_2288877 |
| Conjugate | Unconjugated |
| Purification Method | Antigen affinity purification |
| UNIPROT ID | Q9UBJ2 |
| Storage Buffer | PBS with 0.02% sodium azide and 50% glycerol, pH 7.3. |
| Storage Conditions | Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20 o C storage. 20ul sizes contain 0.1% BSA. |
| IHC protocol for ABCD2 antibody 18179-1-AP | Download protocol |
| IP protocol for ABCD2 antibody 18179-1-AP | Download protocol |
| WB protocol for ABCD2 antibody 18179-1-AP | Download protocol |
| mouse,human | WB Phytomedicine Jiangtang Tiaozhi formula ameliorates MASLD by regulating liver ABCD2/PEX2/ATGL axis-mediated fatty acid metabolic reprogramming. Authors - Runyu Miao View Article |
| mouse | WB Geroscience Coordinated transcriptional upregulation of oxidative metabolism proteins in long-lived endocrine mutant mice Authors - Ahmed M Elmansi View Article |
| Citations | 2 |
| Dilutions | WB : 1:1000-1:8000 IP : 0.5-4.0 ug for IP and 0.5-4.0 ug for 1.0-3.0 mg of total protein lysate for WB IHC : 1:200-1:800 |
| Isotype | IgG |
| Clonality | Polyclonal |
| Clone Number | - |
| Conjugation | Unconjugated |
ABCD2 is a member of the superfamily of ATP-binding cassette (ABC) transporters, and is involved in peroxisomal import of fatty acids and/or fatty acyl-CoAs in the organelle. ABCD2 plays a role in regulation of VLCFAs and energy metabolism, in the degradation and biosynthesis of fatty acids by beta-oxidation (PMID:29397936, 21145416). Protocols Product Specific Protocols IHC protocol for ABCD2 antibody 18179-1-AP Download protocol IP protocol for ABCD2 antibody 18179-1-AP Download protocol WB protocol for ABCD2 antibody 18179-1-AP Download protocol Standard Protocols Click here to view our Standard Protocols
Publications
- Jiangtang Tiaozhi formula ameliorates MASLD by regulating liver ABCD2/PEX2/ATGL axis-mediated fatty acid metabolic reprogramming.
Journal: Phytomedicine | Authors: Runyu Miao | Species: mouse,human | Application: WB - Coordinated transcriptional upregulation of oxidative metabolism proteins in long-lived endocrine mutant mice
Journal: Geroscience | Authors: Ahmed M Elmansi | Species: mouse | Application: WB
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