NLRP7 Recombinant monoclonal antibody 83996-4-RR proteintech
$149.00
In stock
SKU
83996-4-RR
| Catalog Number | 83996-4-RR |
| Synonyms | NOD12, NALP7, NACHT, LRR and PYD domains-containing protein 7, HYDM, CLR19.4 |
| Host | Rabbit |
| Reactivity | human |
| Form | Liquid |
| Formulation | PBS, Azide, Glycerol |
| Applications | IF/ICC, ELISA |
| Host / Isotype | Rabbit / IgG |
| Tested Applications — Positive IF/ICC detected in | K-562 cells |
| Recommended Dilutions — Immunofluorescence (IF)/ICC | IF/ICC : 1:125-1:500 |
| Positive IF/ICC detected in | K-562 cells |
| Immunofluorescence (IF)/ICC | IF/ICC : 1:125-1:500 |
| Tested Reactivity | human |
| Class | Recombinant |
| Type | Antibody |
| Immunogen | CatNo: Ag27465 Product name: Recombinant human NLRP7 protein Source: e coli. -derived, PGEX-4T Tag: GST Domain: 1-171 aa of BC109125 Sequence: MTSPQLEWTLQTLLEQLNEDELKSFKSLLWAFPLEDVLQKTPWSEVEEADGKKLAEILVNTSSENWIRNATVNILEEMNLTELCKMAKAEMMEDGQVQEIDNPELGDAEEDSELAKPGEKEGWRNSMEKQSLVWKNTFWQGDIDNFHDDVTLRNQRFIPFLNPRTPRKLTP Predict reactive species |
| Full Name | NLR family, pyrin domain containing 7 |
| Calculated Molecular Weight | 112 kDa, 115 kDa, 118 kDa |
| GenBank Accession Number | BC109125 |
| Gene Symbol | NLRP7 |
| Gene ID (NCBI) | 199713 |
| RRID | AB_3671571 |
| Conjugate | Unconjugated |
| Purification Method | Protein A purfication |
| UNIPROT ID | Q8WX94 |
| Storage Buffer | PBS with 0.02% sodium azide and 50% glycerol, pH 7.3. |
| Storage Conditions | Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20 o C storage. 20ul sizes contain 0.1% BSA. |
| IF protocol for NLRP7 antibody 83996-4-RR | Download protocol |
| Citations | - |
| Dilutions | IF/ICC : 1:125-1:500 |
| Isotype | IgG |
| Clonality | Recombinant |
| Clone Number | 241120A10 |
| Conjugation | Unconjugated |
NLRP7, also called NALP7 or PYPAF3, is a member of the NOD-like receptors (NLR), a family of proteins that plays a crucial role in the innate immune response. NLRP7 has been reported to emerge from NLRP2 gene. Similar to all inflammasomes, NLRP7 contributes to both pro- and an anti-inflammatory processes, depending on whether it functions in an inflammasome-dependent or independent pathway. The function of NLRP7 inflammasome has also been reported to depend on the master regulatory transcription factor protein that controls cellular inflammation, the NF-kB. In addition to its pro- and anti-inflammatory actions, NLRP7 plays a role in restricting intracellular bacterial replication and can also induce inflammasome assembly upon specific stimulation by FSL-1 (diacylated lipoprotein). Protocols Product Specific Protocols IF protocol for NLRP7 antibody 83996-4-RR Download protocol Standard Protocols Click here to view our Standard Protocols
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