NOVA2 Polyclonal antibody 55002-1-AP proteintech
$149.00
In stock
SKU
55002-1-AP
| Catalog Number | 55002-1-AP |
| Synonyms | ANOVA, Astrocytic NOVA1-like RNA-binding protein, Neuro-oncological ventral antigen 2, NOVA3, RNA binding protein Nova 2 |
| Host | Rabbit |
| Reactivity | human, mouse, rat |
| Form | Liquid |
| Formulation | PBS, Azide, Glycerol |
| Applications | WB, IP, ELISA |
| Host / Isotype | Rabbit / IgG |
| Tested Applications — Positive WB detected in | mouse brain tissue, rat brain tissue |
| Tested Applications — Positive IP detected in | mouse brain tissue |
| Recommended Dilutions — Western Blot (WB) | WB : 1:500-1:2000 |
| Recommended Dilutions — Immunoprecipitation (IP) | IP : 0.5-4.0 ug for 1.0-3.0 mg of total protein lysate |
| Positive WB detected in | mouse brain tissue, rat brain tissue |
| Positive IP detected in | mouse brain tissue |
| Western Blot (WB) | WB : 1:500-1:2000 |
| Immunoprecipitation (IP) | IP : 0.5-4.0 ug for 1.0-3.0 mg of total protein lysate |
| Tested Reactivity | human, mouse, rat |
| Cited Reactivity | human, mouse |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Peptide Predict reactive species |
| Full Name | neuro-oncological ventral antigen 2 |
| Calculated Molecular Weight | 49 kDa |
| Observed Molecular Weight | 50-55 kDa, 65-70 kDa |
| GenBank Accession Number | NM_002516 |
| Gene Symbol | NOVA2 |
| Gene ID (NCBI) | 4858 |
| RRID | AB_10858926 |
| Conjugate | Unconjugated |
| Purification Method | Antigen affinity purification |
| UNIPROT ID | Q9UNW9 |
| Storage Buffer | PBS with 0.02% sodium azide and 50% glycerol, pH 7.3. |
| Storage Conditions | Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20 o C storage. 20ul sizes contain 0.1% BSA. |
| IP protocol for NOVA2 antibody 55002-1-AP | Download protocol |
| WB protocol for NOVA2 antibody 55002-1-AP | Download protocol |
| human | WB medRxiv Spatial proteo-transcriptomic profiling reveals the molecular landscape of borderline ovarian tumors and their invasive progression Authors - Lisa Schweizer View Article |
| mouse | WB Nutrients Nova1 or Bim Deficiency in Pancreatic β-Cells Does Not Alter Multiple Low-Dose Streptozotocin-Induced Diabetes and Diet-Induced Obesity in Mice Authors - Manoja K Brahma View Article |
| mouse,human | WB Int Immunopharmacol Melittin-loaded solid lipid nanoparticles inhibit pulmonary fibrosis via the NOVA2-TGF-β/Smads signaling pathway. Authors - Xinghua Yuan KD Validated View Article |
| Citations | 8 |
| Dilutions | WB : 1:500-1:2000 IP : 0.5-4.0 ug for IP and 0.5-4.0 ug for 1.0-3.0 mg of total protein lysate for WB |
| Isotype | IgG |
| Clonality | Polyclonal |
| Clone Number | - |
| Conjugation | Unconjugated |
NOVA2 also named as ANOVA and NOVA3. It regulates RNA splicing or metabolism in a specific subset of developing neurons. NOVA2 binds single strand RNA. The antibody is specific to NOVA2. By the alternative splicing, NOVA2 can be detected as 50-55 and 70-80 kDa (PMID:26446569, PMID:9789075). Protocols Product Specific Protocols IP protocol for NOVA2 antibody 55002-1-AP Download protocol WB protocol for NOVA2 antibody 55002-1-AP Download protocol Standard Protocols Click here to view our Standard Protocols
Publications
- Aberrant NOVA1 function disrupts alternative splicing in early stages of amyotrophic lateral sclerosis.
Journal: Acta Neuropathol | Authors: Florian Krach | Species: human | Application: WB - PMID: 32271715
Journal: Aging (Albany NY) | Authors: Dongdong Chai KD Validated | Species: mouse | Application: WB - METTL14 reverses liver fibrosis by inhibiting NOVA2 through an m6A-YTHDF2-dependent mechanism
Journal: Hepatol Commun | Authors: Xiaoxue Hou | Species: human | Application: WB - Spatial proteo-transcriptomic profiling reveals the molecular landscape of borderline ovarian tumors and their invasive progression
Journal: medRxiv | Authors: Lisa Schweizer | Species: human | Application: WB - Nova1 or Bim Deficiency in Pancreatic β-Cells Does Not Alter Multiple Low-Dose Streptozotocin-Induced Diabetes and Diet-Induced Obesity in Mice
Journal: Nutrients | Authors: Manoja K Brahma | Species: mouse | Application: WB - Melittin-loaded solid lipid nanoparticles inhibit pulmonary fibrosis via the NOVA2-TGF-β/Smads signaling pathway.
Journal: Int Immunopharmacol | Authors: Xinghua Yuan KD Validated | Species: mouse,human | Application: WB - Sevoflurane inhibits neuronal migration and axon growth in the developing mouse cerebral cortex.
Journal: Aging (Albany NY) | Authors: Dongdong Chai | Species: mouse | Application: WB - Spatial proteo-transcriptomic profiling reveals the molecular landscape of borderline ovarian tumors and their invasive progression
Journal: medRxiv | Authors: Lisa Schweizer | Species: human | Application: WB
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