NPTN Polyclonal antibody 28022-1-AP proteintech

$149.00
In stock
SKU
28022-1-AP
Catalog No.SizePrice (USD)
28022-1-AP-20UL20 μL$149.00
28022-1-AP-150UL150 μL$449.00
Catalog Number28022-1-AP
SynonymsNeuroplastin, GP55, GP65, np55, np65
HostRabbit
Reactivityhuman, rat
FormLiquid
FormulationPBS, Azide, Glycerol
ApplicationsWB, ELISA
Host / IsotypeRabbit / IgG
Tested Applications — Positive WB detected inC6 cells
Recommended Dilutions — Western Blot (WB)WB : 1:200-1:1000
Positive WB detected inC6 cells
Western Blot (WB)WB : 1:200-1:1000
Tested Reactivityhuman, rat
Cited Reactivityhuman
ClassPolyclonal
TypeAntibody
ImmunogenCatNo: Ag27752 Product name: Recombinant human NPTN protein Source: e coli. -derived, PGEX-4T Tag: GST Domain: 185-317 aa of BC030773 Sequence: TKNGVELSATRKNASNMEYRINKPRAEDSGEYHCVYHFVSAPKANATIEVKAAPDITGHKRSENKNEGQDATMYCKSVGYPHPDWIWRKKENGMPMDIVNTSGRFFIINKENYTELNIVNLQITEDPGEYECN Predict reactive species
Full Nameneuroplastin
Calculated Molecular Weight282 aa, 31 kDa
Observed Molecular Weight60 kDa
GenBank Accession NumberBC030773
Gene SymbolNPTN
Gene ID (NCBI)27020
RRIDAB_3086022
ConjugateUnconjugated
Purification MethodAntigen affinity purification
UNIPROT IDQ9Y639
Storage BufferPBS with 0.02% sodium azide and 50% glycerol, pH 7.3.
Storage ConditionsStore at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20 o C storage. 20ul sizes contain 0.1% BSA.
WB protocol for NPTN antibody 28022-1-APDownload protocol
humanWB iScience Development of retinoid nuclear receptor pathway antagonists through targeting aldehyde dehydrogenase 1A3. Authors - Mark Esposito View Article
Citations1
DilutionsWB : 1:200-1:1000
IsotypeIgG
ClonalityPolyclonal
Clone Number-
ConjugationUnconjugated

Neuroplastin (Nptn) is a member of the Ig superfamily and is expressed in two isoforms, Np55 and Np65. Np65 contains three Ig domains (Ig1, Ig2, Ig3). Np55 contains only two (Ig2, Ig3). Np65 regulates synaptic transmission but the function of Np55 is unknown. Expression of the 65 kD neuroplastin (Np65) isoform derived by alternative splicing from the Nptn gene is restricted to brain neurons, whereas the 55 kD isoform (Np55) is present in most cell types but not in glia. (PMID: 33844052, PMID: 33299977, PMID: 27503893,PMID: 27581460) Protocols Product Specific Protocols WB protocol for NPTN antibody 28022-1-AP Download protocol Standard Protocols Click here to view our Standard Protocols

Publications

  1. Development of retinoid nuclear receptor pathway antagonists through targeting aldehyde dehydrogenase 1A3.
    Journal: iScience | Authors: Mark Esposito | Species: human | Application: WB

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