NUP153 Recombinant monoclonal antibody 86622-1-RR proteintech
$149.00
In stock
SKU
86622-1-RR
| Catalog Number | 86622-1-RR |
| Synonyms | 153 kDa nucleoporin, HNUP153, N153, nucleoporin 153kDa, Nucleoporin Nup153 |
| Host | Rabbit |
| Reactivity | human, mouse |
| Form | Liquid |
| Formulation | PBS, Azide, Glycerol |
| Applications | WB, IF/ICC, ELISA |
| Host / Isotype | Rabbit / IgG |
| Tested Applications — Positive WB detected in | HeLa cells, HepG2 cells, MCF-7 cells, A431 cells, K-562 cells, C2C12 cells |
| Tested Applications — Positive IF/ICC detected in | HeLa cells |
| Recommended Dilutions — Western Blot (WB) | WB : 1:2000-1:10000 |
| Recommended Dilutions — Immunofluorescence (IF)/ICC | IF/ICC : 1:250-1:1000 |
| Positive WB detected in | HeLa cells, HepG2 cells, MCF-7 cells, A431 cells, K-562 cells, C2C12 cells |
| Positive IF/ICC detected in | HeLa cells |
| Western Blot (WB) | WB : 1:2000-1:10000 |
| Immunofluorescence (IF)/ICC | IF/ICC : 1:250-1:1000 |
| Tested Reactivity | human, mouse |
| Class | Recombinant |
| Type | Antibody |
| Immunogen | CatNo: Ag5519 Product name: Recombinant human NUP153 protein Source: e coli. -derived, PGEX-4T Tag: GST Domain: 1125-1475 aa of BC052965 Sequence: EEPKCQPVFSFGNSEQTKDENSSKSTFSFSMTKPSEKESEQPAKATFAFGAQTSTTADQGAAKPVFSFLNNSSSSSSTPATSAGGGIFGSSTSSSNPPVATFVFGQSSNPVSSSAFGNTAESSTSQSLLFSQDSKLATTSSTGTAVTPFVFGPGASSNNTTTSGFGFGATTTSSSAGSSFVFGTGPSAPSASPAFGANQTPTFGQSQGASQPNPPGFGSISSSTALFPTGSQPAPPTFGTVSSSSQPPVFGQQPSQSAFGSGTTPNSSSAFQFGSSTTNFNFTNNSPSGVFTFGANSSTPAASAQPSGSGGFPFNQSPAAFTVGSNGKNVFSSSGTSFSGRKIKTAVRRRK Predict reactive species |
| Full Name | nucleoporin 153kDa |
| Calculated Molecular Weight | 154 kDa |
| Observed Molecular Weight | 160-170 kDa |
| GenBank Accession Number | BC052965 |
| Gene Symbol | NUP153 |
| Gene ID (NCBI) | 9972 |
| RRID | AB_3745015 |
| Conjugate | Unconjugated |
| Purification Method | Protein A purification |
| UNIPROT ID | P49790 |
| Storage Buffer | PBS with 0.02% sodium azide and 50% glycerol, pH 7.3. |
| Storage Conditions | Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20 o C storage. 20ul sizes contain 0.1% BSA. |
| IF protocol for NUP153 antibody 86622-1-RR | Download protocol |
| WB protocol for NUP153 antibody 86622-1-RR | Download protocol |
| Citations | - |
| Dilutions | WB : 1:2000-1:10000 IF/ICC : 1:250-1:1000 |
| Isotype | IgG |
| Clonality | Recombinant |
| Clone Number | 251519G11 |
| Conjugation | Unconjugated |
NUP153 is an FG-repeat containing NUP, contains a high-affinity site for importin-β, localizes on the nucleoplasmic face of the nuclear pore and is required for assembly of the nuclear basket and import of a subset of nuclear proteins [PMID:18845677]. NUP153 also facilitates nuclear export of mRNA and ribonucleoprotein particles and may have additional functions within the nucleus [PMID:16195343]. The 53BP1-NUP153/importin-β pathway as an important aspect of the DDR network add to an emerging evidence of subcellular trafficking as an integral part of genome surveillance [PMID:22075984]. Protocols Product Specific Protocols IF protocol for NUP153 antibody 86622-1-RR Download protocol WB protocol for NUP153 antibody 86622-1-RR Download protocol Standard Protocols Click here to view our Standard Protocols
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