NeutraControl M-CSF Mouse McAb 69533-1-Ig proteintech
$189.00
In stock
SKU
69533-1-Ig
| Catalog Number | 69533-1-Ig |
| Synonyms | M-CSF, 4B3C1, CSF 1, CSF1, CSF-1 |
| Host | Mouse |
| Reactivity | human |
| Form | Lyophilized Powder |
| Formulation | Lyophilized |
| Endotoxin | <0.1 EU/μg |
| Applications | ELISA, Non-Neutralization |
| Reconstitution | This product was lyophilized from a 0.2 μm filtered solution in PBS. Reconstitute at 1.0 mg/mL in sterile H2O before use. |
| Host / Isotype | Mouse / IgG1 |
| Tested Reactivity | human |
| Class | Monoclonal |
| Type | Antibody |
| Immunogen | CatNo: Product name: HumanKine® recombinant human M-CSF protein Source: -derived, Tag: Domain: of Sequence: Predict reactive species |
| Full Name | colony stimulating factor 1 (macrophage) |
| Gene Symbol | M-CSF |
| Gene ID (NCBI) | 1435 |
| RRID | AB_3085331 |
| Conjugate | Unconjugated |
| Purification Method | Protein G purification |
| UNIPROT ID | P09603 |
| Storage Buffer | Sterile PBS, pH 7.4. |
| Stability and Storage | Lyophilized antibodies are stable for 1 year from the date of receipt if stored between (-20°C) and (-80°C). Upon reconstitution we recommend that the solution can be stored at (4°C) for short term or at (-20°C) to (-80°C) for long term. Repeated freeze thaw cycles should be avoided with reconstituted products. |
| Citations | - |
| Dilutions | NON-NEUTRALIZATION : 1:10-1:100 ELISA : 1:10-1:100 |
| Isotype | IgG1 |
| Clonality | Monoclonal |
| Clone Number | 4B3C1 |
| Conjugation | Unconjugated |
M-CSF plays an essential role in the regulation of survival, proliferation, and differentiation of hematopoietic precursor cells, especially mononuclear phagocytes. M-CSF promotes the release of proinflammatory chemokines and thereby plays an important role in innate immunity and in inflammatory processes. It also plays an important role in the regulation of osteoclast proliferation and differentiation, the regulation of bone resorption, and is required for normal bone development. On the cellular level, M-CSF promotes reorganization of the actin cytoskeleton, regulates the formation of membrane ruffles, cell adhesion, and cell migration, and plays a role in lipoprotein clearance. This antibody is a neutralizing control antibody for M-CSF, the immunogen is the same as Neutrakine 69033-Ig but could not neutralize human M-CSF.
Reviews
Write Your Own Review
Related Products
Check items to add to the cart or
