P2RX6 Recombinant monoclonal antibody, PBS Only 84458-4-PBS proteintech
$699.00
In stock
SKU
84458-4-PBS
| Catalog Number | 84458-4-PBS |
| Synonyms | P2XM, P2X6, P2X purinoceptor 6, P2RXL1, ATP receptor |
| Host | Rabbit |
| Reactivity | human, mouse |
| Form | Liquid |
| Formulation | PBS Only |
| Applications | WB, Indirect ELISA |
| Host / Isotype | Rabbit / IgG |
| Tested Reactivity | human, mouse |
| Class | Recombinant |
| Type | Antibody |
| Immunogen | CatNo: Ag12331 Product name: Recombinant human P2RX6 protein Source: e coli. -derived, PGEX-4T Tag: GST Domain: 1-330 aa of BC033488 Sequence: MGSPGATTGWGLLDYKTEKYVMTRNWRVGALQRLLQFGIVVYVVGWALLAKKGYQERDLEPQFSIITKLKGVSVTQIKELGNRLWDVADFVKPPQGENVFFLVTNFLVTPAQVQGRCPEHPSVPLANCWVDEDCPEGEGGTHSHGVKTGQCVVFNGTHRTCEIWSWCPVESGVVPSRPLLAQAQNFTLFIKNTVTFSKFNFSKSNALETWDPTYFKHCRYEPQFSPYCPVFRIGDLVAKAGGTFEDLALLGGSVGIRVHWDCDLDTGDSGCWPHYSFQLQEKSYNFRTATHWWEQPGVEARTLLKLYGIRFDILVTGQAGKFGLIPTAVT Predict reactive species |
| Full Name | purinergic receptor P2X, ligand-gated ion channel, 6 |
| Calculated Molecular Weight | 431 aa, 48 kDa |
| Observed Molecular Weight | 45 kDa |
| GenBank Accession Number | BC033488 |
| Gene Symbol | P2RX6 |
| Gene ID (NCBI) | 9127 |
| RRID | AB_3671983 |
| Conjugate | Unconjugated |
| Purification Method | Protein A purfication |
| UNIPROT ID | O15547 |
| Storage Buffer | PBS only, pH 7.3. |
| Storage Conditions | Store at -80°C. |
| Citations | - |
| Isotype | IgG |
| Clonality | Recombinant |
| Clone Number | 241620B10 |
| Conjugation | Unconjugated |
The P2 receptors have two subfamilies in mammalian cells, P2X and P2Y. P2X family of ligand-gated ion channel receptors have seven members, P2RX1-7, which all constitute non-selective cation channels proposed to be functional under a homo- or heterotrimeric association. P2RX6 is predominantly expressed in skeletal muscle, and regulated by p53. It's reported that ATP might increase renal cell carcinoma cells migration and invasion through P2RX6.(PMID: 31159832, PMID:9242461)
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