PDGFR beta/CD140b Monoclonal antibody 60535-13-Ig proteintech
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60535-13-Ig
| Catalog Number | 60535-13-Ig |
| Synonyms | PDGFRB, Beta platelet-derived growth factor receptor, Beta-type platelet-derived growth factor receptor, CD140 antigen-like family member B, CD140B |
| Host | Mouse |
| Reactivity | human |
| Form | Liquid |
| Formulation | PBS, Azide, Glycerol |
| Applications | WB, ELISA |
| Host / Isotype | Mouse / IgG2a |
| Tested Applications — Positive WB detected in | SH-SY5Y cells, U2OS cells, SK-N-SH cells |
| Recommended Dilutions — Western Blot (WB) | WB : 1:2000-1:10000 |
| Positive WB detected in | SH-SY5Y cells, U2OS cells, SK-N-SH cells |
| Western Blot (WB) | WB : 1:2000-1:10000 |
| Tested Reactivity | human |
| Class | Monoclonal |
| Type | Antibody |
| Immunogen | CatNo: Eg0147 Product name: Recombinant Human PDGFR beta/CD140b protein (Myc Tag, His Tag) Source: mammalian cells -derived, pHZ-KIsec Tag: Myc & 6*His Domain: 33-531 aa of BC032224 Sequence: LVVTPPGPELVLNVSSTFVLTCSGSAPVVWERMSQEPPQEMAKAQDGTFSSVLTLTNLTGLDTGEYFCTHNDSRGLETDERKRLYIFVPDPTVGFLPNDAEELFIFLTEITEITIPCRVTDPQLVVTLHEKKGDVALPVPYDHQRGFFGIFEDRSYICKTTIGDREVDSDAYYVYRLQVSSINVSVNAVQTVVRQGENITLMCIVIGNEVVNFEWTYPRKESGRLVEPVTDFLLDMPYHIRSILHIPSAELEDSGTYTCNVTESVNDHQDEKAINITVVESGYVRLLGEVGTLQFAELHRSRTLQVVFEAYPPPTVLWFKDNRTLGDSSAGEIALSTRNVSETRYVSELTLVRVKVAEAGHYTMRAFHEDAEVQLSFQLQINVPVRVLELSESHPDSGEQTVRCRGRGMPQPNIIWSACRDLKRCPRELPPTLLGNSSEEESQLETNVTYWEEEQEFEVVSTLRLQHVDRPLSVRCTLRNAVGQDTQEVIVVPHSLPFK Predict reactive species |
| Full Name | platelet-derived growth factor receptor, beta polypeptide |
| Calculated Molecular Weight | 1106 aa, 124 kDa |
| Observed Molecular Weight | 160-180 kDa |
| GenBank Accession Number | BC032224 |
| Gene Symbol | PDGFR beta |
| Gene ID (NCBI) | 5159 |
| RRID | AB_3743219 |
| Conjugate | Unconjugated |
| Purification Method | Protein A purification |
| UNIPROT ID | P09619 |
| Storage Buffer | PBS with 0.02% sodium azide and 50% glycerol, pH 7.3. |
| Storage Conditions | Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20 o C storage. 20ul sizes contain 0.1% BSA. |
| WB protocol for PDGFR beta/CD140b antibody 60535-13-Ig | Download protocol |
| Citations | - |
| Dilutions | WB : 1:2000-1:10000 |
| Isotype | IgG2a |
| Clonality | Monoclonal |
| Clone Number | 4E2D5 |
| Conjugation | Unconjugated |
PDGFRs are receptor tyrosine kinases with an extracellular ligand-binding domain and a cytoplasmic enzymatic domain. The signaling activity of PDGFRs is tightly regulated by an autoinhibitory allosteric conformation, and requires ligand-induced receptor dimerization at the cell surface to alleviate autoinhibition and achieve physiological activity (PMID: 21664579). PDGFR beta (platelet-derived growth factor receptor- β)/CD140b is a constitutive marker expressed by ASCs in the angiogenic behavior of human retinal endothelial cells (HREs). CD140b (PDGFRβ) plays a crucial role in controlling the intrinsic proliferation (PMID: 30976657) Protocols Product Specific Protocols WB protocol for PDGFR beta/CD140b antibody 60535-13-Ig Download protocol Standard Protocols Click here to view our Standard Protocols
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