Serpin F1/PEDF Monoclonal antibody, PBS Only 66554-1-PBS proteintech
$699.00
In stock
SKU
66554-1-PBS
| Catalog Number | 66554-1-PBS |
| Synonyms | PEDF, PIG35, 2C5C8, Cell proliferation-inducing gene 35 protein, EPC 1 |
| Host | Mouse |
| Reactivity | human, pig |
| Form | Liquid |
| Formulation | PBS Only |
| Applications | WB, Indirect ELISA |
| Host / Isotype | Mouse / IgG1 |
| Tested Reactivity | human, pig |
| Class | Monoclonal |
| Type | Antibody |
| Immunogen | CatNo: Ag26660 Product name: Recombinant human SERPINF1 protein Source: e coli. -derived, PGEX-4T Tag: GST Domain: 282-403 aa of BC013984 Sequence: VTQNLTLIEESLTSEFIHDIDRELKTVQAVLTVPKLKLSYEGEVTKSLQEMKLQSLFDSPDFSKITGKPIKLTQVEHRAGFEWNEDGAGTTPSPGLQPAHLTFPLDYHLNQPFIFVLRDTDT Predict reactive species |
| Full Name | serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1 |
| Calculated Molecular Weight | 418 aa, 46 kDa |
| Observed Molecular Weight | 46-50 kDa |
| GenBank Accession Number | BC013984 |
| Gene Symbol | PEDF |
| Gene ID (NCBI) | 5176 |
| RRID | AB_2881916 |
| Conjugate | Unconjugated |
| Purification Method | Protein A purification |
| UNIPROT ID | P36955 |
| Storage Buffer | PBS only, pH 7.3. |
| Storage Conditions | Store at -80°C. |
| Citations | - |
| Isotype | IgG1 |
| Clonality | Monoclonal |
| Clone Number | 2C5C8 |
| Conjugation | Unconjugated |
PEDF also known as serpin F1 (SERPINF1), is a multifunctional secreted protein that has anti-angiogenic, anti-tumorigenic, and neurotrophic functionsis. It is an approximately 50-kDa secreted protein that is widely expressed, including by osteoblasts and osteoclasts. PEDF is also one of the most abundant secretory products of adipocytes, and circulating concentrations of PEDF correlate positively with body fat mass and INS resistance. PEDF is a neurotrophic factor involved in neuronal differentiation in retinoblastoma cells. Mutations in this gene were found in individuals with osteogenesis imperfecta, type VI.
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