PFDN4 Polyclonal antibody 16045-1-AP proteintech
$149.00
In stock
SKU
16045-1-AP
| Catalog Number | 16045-1-AP |
| Synonyms | C1, PFD4, PFDN4, prefoldin 4, prefoldin subunit 4, Protein C 1 |
| Host | Rabbit |
| Reactivity | human and More (1) |
| Reactivity | human, mouse |
| Form | Liquid |
| Formulation | PBS, Azide, Glycerol |
| Applications | WB, IHC, IF, ELISA |
| Applications | WB, IHC, ELISA |
| Host / Isotype | Rabbit / IgG |
| Tested Applications — Positive WB detected in | MCF-7 cells, Raji cells, THP-1 cells |
| Tested Applications — Positive IHC detected in | human breast cancer tissue Note: suggested antigen retrieval with TE buffer pH 9.0; (*) Alternatively, antigen retrieval may be performed with citrate buffer pH 6.0 |
| Recommended Dilutions — Western Blot (WB) | WB : 1:500-1:2000 |
| Recommended Dilutions — Immunohistochemistry (IHC) | IHC : 1:50-1:500 |
| Positive WB detected in | MCF-7 cells, Raji cells, THP-1 cells |
| Positive IHC detected in | human breast cancer tissue Note: suggested antigen retrieval with TE buffer pH 9.0; (*) Alternatively, antigen retrieval may be performed with citrate buffer pH 6.0 |
| Western Blot (WB) | WB : 1:500-1:2000 |
| Immunohistochemistry (IHC) | IHC : 1:50-1:500 |
| Tested Reactivity | human |
| Cited Reactivity | human, mouse |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | CatNo: Ag8938 Product name: Recombinant human PFDN4 protein Source: e coli. -derived, PGEX-4T Tag: GST Domain: 1-134 aa of BC010953 Sequence: MAATMKKAAAEDVNVTFEDQQKINKFARNTSRITELKEEIEVKKKQLQNLEDACDDIMLADDDCLMIPYQIGDVFISHSQEETQEMLEEAKKNLQEEIDALESRVESIQRVLADLKVQLYAKFGSNINLEADES Predict reactive species |
| Full Name | prefoldin subunit 4 |
| Calculated Molecular Weight | 134 aa, 15 kDa |
| Observed Molecular Weight | 15-20 kDa |
| GenBank Accession Number | BC010953 |
| Gene Symbol | PFDN4 |
| Gene ID (NCBI) | 5203 |
| RRID | AB_2162573 |
| Conjugate | Unconjugated |
| Purification Method | Antigen affinity purification |
| UNIPROT ID | Q9NQP4 |
| Storage Buffer | PBS with 0.02% sodium azide and 50% glycerol, pH 7.3. |
| Storage Conditions | Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20 o C storage. 20ul sizes contain 0.1% BSA. |
| IHC protocol for PFDN4 antibody 16045-1-AP | Download protocol |
| WB protocol for PFDN4 antibody 16045-1-AP | Download protocol |
| human | WB J Exp Clin Cancer Res SNRPC promotes chemoresistance in Wilms tumor via the NF-κB-CXCL17 axis regulating M2-Type TAMs infiltration and targeted nanotherapy research. Authors - Xiangpan Kong View Article |
| mouse | WB,IF Biomark Res Single-cell and bulk RNA-seq unveils the immune infiltration landscape associated with cuproptosis in cerebral cavernous malformations Authors - Chengwei Chen View Article |
| Citations | 4 |
| Dilutions | WB : 1:500-1:2000 IHC : 1:50-1:500 |
| Isotype | IgG |
| Clonality | Polyclonal |
| Clone Number | - |
| Conjugation | Unconjugated |
The human PFDN4, prefoldin 4, is a subunit of the heterohexameric chaperone protein and belongs to the prefoldin family. The encoded protein is one of six subunits of prefoldin, a molecular chaperone complex that binds and stabilizes newly synthesized polypeptides, thereby allowing them to fold correctly. Previous reports have shown that PFDN4 is upregulated in breast cancer cell lines and tumor tissues (PMID: 11381030; PMID: 9630229). PFDN4 expression may be a prognostic factor in colorectal cancer (PMID: 20552408). Protocols Product Specific Protocols IHC protocol for PFDN4 antibody 16045-1-AP Download protocol WB protocol for PFDN4 antibody 16045-1-AP Download protocol Standard Protocols Click here to view our Standard Protocols
Publications
- miR-26a regulates extracellular vesicle secretion from prostate cancer cells via targeting SHC4, PFDN4, and CHORDC1.
Journal: Sci Adv | Authors: Fumihiko Urabe | Species: human | Application: WB - Prefoldin complex promotes interferon-stimulated gene expression and is inhibited by rotavirus VP3
Journal: Nat Commun | Authors: Yinxing Zhu - SNRPC promotes chemoresistance in Wilms tumor via the NF-κB-CXCL17 axis regulating M2-Type TAMs infiltration and targeted nanotherapy research.
Journal: J Exp Clin Cancer Res | Authors: Xiangpan Kong | Species: human | Application: WB - Single-cell and bulk RNA-seq unveils the immune infiltration landscape associated with cuproptosis in cerebral cavernous malformations
Journal: Biomark Res | Authors: Chengwei Chen | Species: mouse | Application: WB,IF
Reviews
Write Your Own Review
Related Products
Check items to add to the cart or
