PRMT5 Monoclonal antibody 68534-1-Ig proteintech
$149.00
In stock
SKU
68534-1-Ig
| Catalog Number | 68534-1-Ig |
| Synonyms | 72 kDa ICln binding protein, HRMT1L5, IBP72, Jak binding protein 1, JBP1, PRMT5, SKB1, SKB1 homolog, SKB1Hs |
| Host | Mouse |
| Reactivity | Human, rat |
| Reactivity | human, rat |
| Form | Liquid |
| Formulation | PBS, Azide, Glycerol |
| Applications | WB, ELISA |
| Host / Isotype | Mouse / IgG1 |
| Tested Applications — Positive WB detected in | MCF-7 cells, HeLa cells, HEK-293 cells, HepG2 cells, Jurkat cells, HSC-T6 cells |
| Recommended Dilutions — Western Blot (WB) | WB : 1:5000-1:50000 |
| Positive WB detected in | MCF-7 cells, HeLa cells, HEK-293 cells, HepG2 cells, Jurkat cells, HSC-T6 cells |
| Western Blot (WB) | WB : 1:5000-1:50000 |
| Tested Reactivity | Human, rat |
| Class | Monoclonal |
| Type | Antibody |
| Immunogen | CatNo: Ag9678 Product name: Recombinant human PRMT5 protein Source: e coli. -derived, PET28a Tag: 6*His Domain: 283-637 aa of BC025979 Sequence: YLEYLSQNRPPPNAYELFAKGYEDYLQSPLQPLMDNLESQTYEVFEKDPIKYSQYQQAIYKCLLDRVPEEEKDTNVQVLMVLGAGRGPLVNASLRAAKQADRRIKLYAVEKNPNAVVTLENWQFEEWGSQVTVVSSDMREWVAPEKADIIVSELLGSFADNELSPECLDGAQHFLKDDGVSIPGEYTSFLAPISSSKLYNEVRACREKDRDPEAQFEMPYVVRLHNFHQLSAPQPCFTFSHPNRDPMIDNNRYCTLEFPVEVNTVLHGFAGYFETVLYQDITLSIRPETHSPGMFSWFPILFPIKQPITVREGQTICVRFWRCSNSKKVWYEWAVTAPVCSAIHNPTGRSYTIGL Predict reactive species |
| Full Name | protein arginine methyltransferase 5 |
| Calculated Molecular Weight | 637 aa, 73 kDa |
| Observed Molecular Weight | 68 kDa |
| GenBank Accession Number | BC025979 |
| Gene Symbol | PRMT5 |
| Gene ID (NCBI) | 10419 |
| RRID | AB_3085242 |
| Conjugate | Unconjugated |
| Purification Method | Protein G purification |
| UNIPROT ID | O14744 |
| Storage Buffer | PBS with 0.02% sodium azide and 50% glycerol, pH 7.3. |
| Storage Conditions | Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20 o C storage. 20ul sizes contain 0.1% BSA. |
| WB protocol for PRMT5 antibody 68534-1-Ig | Download protocol |
| Citations | - |
| Dilutions | WB : 1:5000-1:50000 |
| Isotype | IgG1 |
| Clonality | Monoclonal |
| Clone Number | 4A1B5 |
| Conjugation | Unconjugated |
PRMT5 is a Type II enzyme that catalyzes arginine monomethylation and symmetric dimethylation (Rme1 and Rme2s). The many targets of PRMT5 include ribosomal proteins, the histone chaperone nucleoplasmin, p53, and histones. PRMT5 is frequently observed in a complex with the cofactor, methylosome protein 50 (MEP50), which is required for PRMT5 activity. PRMT5 is upregulated in several human malignancies, including lymphomas, lung cancer, breast cancer and colorectal cancer. Protocols Product Specific Protocols WB protocol for PRMT5 antibody 68534-1-Ig Download protocol Standard Protocols Click here to view our Standard Protocols
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